Search Results - "Abdelbaset, Mahmoud S."

Discovery of novel thienoquinoline-2-carboxamide chalcone derivatives as antiproliferative EGFR tyrosine kinase inhibitors by Abdelbaset, Mahmoud S., Abdel-Aziz, Mohamed, Ramadan, Mohamed, Abdelrahman, Mostafa H., Abbas Bukhari, Syed Nasir, Ali, Taha F.S., Abuo-Rahma, Gamal El-Din A.

“…[Display omitted] •Novel thienoquinoline-2-carboxamide-chalcone derivatives.•Structural elucidation.•Good Antiproliferaive Activity.•EGFR-kinase…”
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Novel pyrrol-2(3H)-ones and pyridazin-3(2H)-ones carrying quinoline scaffold as anti-proliferative tubulin polymerization inhibitors by Abdelbaset, Mahmoud S., Abuo-Rahma, Gamal El-Din A., Abdelrahman, Mostafa H., Ramadan, Mohamed, Youssif, Bahaa G.M., Bukhari, Syed Nasir Abbas, Mohamed, Mamdouh F.A., Abdel-Aziz, Mohamed

“…[Display omitted] •Novel quinolinyl pyrrolone and quinolinyl pyridazinone derivatives.•Antiproliferative activity.•BRAF kinase inhibition.•Tubulin…”
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Novel quinoline derivatives carrying nitrones/oximes nitric oxide donors: Design, synthesis, antiproliferative and caspase‐3 activation activities by Abdelbaset, Mahmoud S., Abdel‐Aziz, Mohamed, Abuo‐Rahma, Gamal El‐Din A., Abdelrahman, Mostafa H., Ramadan, Mohamed, Youssif, Bahaa G. M.

“…Novel quinoline derivatives carrying nitrones and oxime as nitric oxide donors were prepared and characterized using different spectroscopic techniques…”
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3,7-bis-benzylidene hydrazide ciprofloxacin derivatives as promising antiproliferative dual TOP I & TOP II isomerases inhibitors by Samir, Mohamed, Ramadan, Mohamed, Abdelrahman, Mostafa H., Abdelbaset, Mahmoud S., Abourehab, Mohammed A.S., Abdel-Aziz, Mohamed, Abuo-Rahma, Gamal El-Din A.

“…[Display omitted] •Design and synthesis of 3,7-bis-benzylidene derivatives of ciprofloxacin 4-j.•4e, 4 h and 4i showed promising antiproliferative activity…”
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Design, synthesis, and biological evaluation of new series of pyrrol-2(3H)-one and pyridazin-3(2H)-one derivatives as tubulin polymerization inhibitors by Abdelbaset, Mahmoud S., Abdelrahman, Mostafa H., Bukhari, Syed Nasir Abbas, Gouda, Ahmed M., Youssif, Bahaa G.M., Abdel-Aziz, Mohamed, Abuo-Rahma, Gamal El-Din A.

“…[Display omitted] •Novel Pyrrol-2-one, Pyridazin-3(2H)-one derivatives has been synthesized and tested by NCI for anticancer activity.•IVc and IVg showed…”
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New Ciprofloxacin–Pyrazolopyrimidine Hybrids as Topoisomerase IV and Gyrase Inhibitors against MRSA AUMC 261 by Samir, Mohamed, Ramadan, Mohamed, Abdelrahman, Mostafa H., Abdelbaset, Mahmoud S., Abdel‐Aziz, Mohamed, Mohamed Halby, Hamada, Abuo‐Rahma, Gamal El‐Din A.

“…Eleven novel ciprofloxacin–pyrazolopyrimidine hybrids 4 a–k were synthesized and structurally elucidated using NMR, elemental analysis, and mass spectrometry…”
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