Search Results - "AbdelHamid, Sherihan"

Upregulation of miR-96-5p by bone marrow mesenchymal stem cells and their exosomes alleviate non-alcoholic steatohepatitis: Emphasis on caspase-2 signaling inhibition by El-Derany, Marwa O., AbdelHamid, Sherihan G.

“…BM-MSCs or BM-MSCs-Exo upregulated the hepatic miRNA-96-5p which targets caspase-2 in HFD-induced NASH. Resulting in significant downregulation of fatty acid…”
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Interactome battling of lncRNA CCDC144NL-AS1: Its role in the emergence and ferocity of cancer and beyond by Abd El Fattah, Yasmine K., Abulsoud, Ahmed I., AbdelHamid, Sherihan G., Hamdy, Nadia M.

“…Long non-coding RNAs (lncRNAs) were, once, viewed as “noise” for transcription. Recently, many lncRNAs are functionally linked to several human disorders,…”
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CCDC144NL-AS1/hsa-miR-143-3p/HMGA2 interaction: In-silico and clinically implicated in CRC progression, correlated to tumor stage and size in case-controlled study; step toward ncRNA precision by Abd El Fattah, Yasmine K., Abulsoud, Ahmed I., AbdelHamid, Sherihan G., AbdelHalim, Sherif, Hamdy, Nadia M.

“…Unravel the regulatory mechanism of lncRNA CCDC144NL-AS1 in CRC hsa-miR-143-3p, downstream protein HMGA2 interaction arm, association with clinicopathological…”
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Comparing cefotaxime and ceftriaxone in combating meningitis through nose-to-brain delivery using bio/chemoinformatics tools by Hathout, Rania M., Abdelhamid, Sherihan G., El-Housseiny, Ghadir S., Metwally, Abdelkader A.

“…Bio/chemoinformatics tools can be deployed to compare antimicrobial agents aiming to select an efficient nose-to-brain formulation targeting the meningitis…”
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Tetrandrine ameliorated atherosclerosis in vitamin D3/high cholesterol diet-challenged rats via modulation of miR-34a and Wnt5a/Ror2/ABCA1/NF-kB trajectory by El Zouka, Yasmin, Sheta, Eman, Abdelrazek Salama, Mona, Selima, Eman, Refaat, Rowaida, Salaheldin Abdelhamid Ibrahim, Sherihan

“…Atherosclerosis (AS) is a major cause of cardiovascular diseases that may lead to mortality. This study aimed to evaluate the therapeutic potential of…”
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Genetic and Epigenetic Regulation of MEFV Gene and Their Impact on Clinical Outcome in Auto-Inflammatory Familial Mediterranean Fever Patients by Zekry, May E, Sallam, Al-Aliaa M, AbdelHamid, Sherihan G, Zarouk, Waheba A, El-Bassyouni, Hala T, El-Mesallamy, Hala O

“…Epigenetic modifications play a pivotal role in autoimmune/inflammatory disorders and could establish a bridge between personalized medicine and disease…”
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BRCA1 and BRCA2 truncating mutations and variants of unknown significance in Egyptian female breast cancer patients by AbdelHamid, Sherihan G., Zekri, Abdel-Rahman N., AbdelAziz, Hany M., El-Mesallamy, Hala O.

“…•Breast cancer is the leading cause of cancer death in economically developing countries.•Knowledge of the contribution of BRCA1/2 mutations to the burden of…”
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Metformin and omega-3 fish oil elicit anti-inflammatory effects via modulation of some dysregulated micro RNAs expression and signaling pathways in experimental induced arthritis by El-Sayyad, Shorouk M., Ali, Mennatallah A., kandil, Lamia S., Ragab, Ghada M., Abdelhamid Ibrahim, Sherihan S.

“…•Combination of Metformin and omega-3 amended the arthrogram score, hind paw swelling, serum TNF-α and interleukin (IL)-1β levels in adjuvant induced arthritis…”
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Bone Marrow Mesenchymal Stem Cells and Their Derived Extracellular Vesicles Attenuate Non-Alcoholic Steatohepatitis-Induced Cardiotoxicity via Modulating Cardiac Mechanisms by El-Derany, Marwa O, AbdelHamid, Sherihan G

“…Cardiovascular-disease (CVD)-related mortality has been fueled by the upsurge of non-alcoholic steatohepatitis (NASH). Mesenchymal stem cells (MSCs) were…”
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Deciphering epigenetic(s) role in modulating susceptibility to and severity of COVID-19 infection and/or outcome: a systematic rapid review by AbdelHamid, Sherihan G., Refaat, Aya A., Benjamin, Anthony M., Elmawardy, Laila A., Elgendy, Lougine A., Manolly, Mark M., Elmaksoud, Nada Abd, Sherif, Nourhan, Hamdy, Nadia M.

“…COVID-19 pandemic waves hitting worldwide result in drastic postinfection complications with interindividual variations, which raised the question for the…”
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Amelioration of Diabetic Nephropathy by Targeting Autophagy via Rapamycin or Fasting: Relation to Cell Apoptosis/Survival by Gouda, Khaled, AbdelHamid, Sherihan, Mansour, Ahmed, Omar, Nesreen, El-Mesallamy, Hala

“…Autophagy has been demonstrated to have a beneficial effect on diabetic nephropathy (DN). Rapamycin, an inhibitor of mTOR, was shown to stimulate β-cell…”
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Astrocyte-Targeted Transporter-Utilizing Derivatives of Ferulic Acid Can Have Multifunctional Effects Ameliorating Inflammation and Oxidative Stress in the Brain by Huttunen, Kristiina M., Ibrahim, Sherihan Abdelhamid, Huttunen, Johanna, Montaser, Ahmed

“…Ferulic acid (FA) is a natural phenolic antioxidant, which can exert also several other beneficial effects to combat neuroinflammation and neurodegenerative…”
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Monocytes subsets altered distribution and dysregulated plasma hsa-miR-21-5p and hsa-miR-155-5p in HCV-linked liver cirrhosis progression to hepatocellular carcinoma by Hammad, Reham, Eldosoky, Mona A., Elmadbouly, Asmaa A., Aglan, Reda Badr, AbdelHamid, Sherihan G., Zaky, Samy, Ali, Elham, Abd El Hakam, Fatma El-Zahraa, Mosaad, Alshaimaa M., Abdelmageed, Neamat A., Kotb, Fatma M., Kotb, Hend G., Hady, Ahmed A., Abo-Elkheir, Omaima I., Kujumdshiev, Sandy, Sack, Ulrich, Lambert, Claude, Hamdy, Nadia M.

“…Purpose The authors aim to investigate the altered monocytes subsets distribution in liver cirrhosis (LC) and subsequent hepatocellular carcinoma (HCC) in…”
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Serum MicroRNA-96 As a Potential Diagnostic Marker in Breast Cancer by AbdelHamid, Sherihan, AbdelAziz, Hany, Kamal, Amany

“…Breast cancer is the most commonly occurring cancer in women and the fifth leading cause of global cancer mortality. MicroRNAs (miRNAs) are essential…”
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Chloroquine and hydroxychloroquine for combating COVID-19: Investigating efficacy and hypothesizing new formulations using Bio/chemoinformatics tools by Hathout, Rania M., Abdelhamid, Sherihan G., Metwally, Abdelkader A.

“…Chloroquine (CQ) and hydroxychloroquine (HCQ) are undergoing several clinical trials for evaluating their efficacy and safety as antiviral drugs. Yet, there is…”
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Prognostic Impact of BRCA1 and BRCA2 Mutations on Long-Term Survival Outcomes in Egyptian Female Breast Cancer Patients by AbdelHamid, Sherihan, El-Mesallamy, Hala, Aziz, Hany Abdel, Zekri, Abdel-Rahman

“…Evidence on the prognostic relevance of mutations on breast cancer survival is still debatable. To address this ambiguity, we sought to elucidate the impact of…”
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Diagnostic Significance of hsa-miR-21-5p, hsa-miR-192-5p, hsa-miR-155-5p, hsa-miR-199a-5p Panel and Ratios in Hepatocellular Carcinoma on Top of Liver Cirrhosis in HCV-Infected Patients by Eldosoky, Mona A, Hammad, Reham, Elmadbouly, Asmaa A, Aglan, Reda Badr, Abdel-Hamid, Sherihan G, Alboraie, Mohamed, Hassan, Donia Ahmed, Shaheen, Mohamed A, Rushdi, Areej, Ahmed, Reem M, Abdelbadea, Alzahra, Abdelmageed, Neamat A, Elshafei, Ahmed, Ali, Elham, Abo-Elkheir, Omaima I, Zaky, Samy, Hamdy, Nadia M, Lambert, Claude

“…Early hepatocellular carcinoma (HCC) diagnosis is challenging. Moreover, for patients with alpha-fetoprotein (AFP)-negative HCC, this challenge is augmented…”
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Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories by Ali, Nermeen B., Abdelhamid Ibrahim, Sherihan Salaheldin, Alsherbiny, Muhammad A., Sheta, Eman, El-Shiekh, Riham A., Ashour, Rehab M., El-Gazar, Amira A., Ragab, Ghada M., El-Gayed, Sabah H., Li, Chun Guang, Abdel-Sattar, Essam

“…The utilization of plants with therapeutic properties in traditional medicine has a longstanding practice. Among them, the well-known Allium cepa L. commonly…”
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Anti-neoplastic action of Cimetidine/Vitamin C on histamine and the PI3K/AKT/mTOR pathway in Ehrlich breast cancer by Ibrahim, Sherihan Salaheldin Abdelhamid, El-Aal, Sarah A. Abd, Reda, Ahmed M., Achy, Samar El, Shahine, Yasmine

“…The main focus of our study is to assess the anti-cancer activity of cimetidine and vitamin C via combating the tumor supportive role of mast cell mediators…”
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The gastroprotective effect of Yucca filamentosa standardized crude leaves extract versus its nano-cubosomal formulation in ethanol-induced gastric injury by Salaheldin Abdelhamid Ibrahim, Sherihan, Bassam, Samar M., El-Hawary, Seham, Sheta, Eman, Masoud, Inas M., El-Zahaby, Sally A., Al-Mahallawi, Abdulaziz M., Hammad, Ghada O.

“…[Display omitted] •YF nano-cubosomal formulation showed superior gastroprotective effect than its crude leaves extract in ethanol induced gastric injury…”
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