Search Results - "Abdel Moty, Samia"

Design and synthesis of some substituted thiazolo[3,2-a]pyrimidine derivatives of potential biological activities by Abdel Moty, Samia G., Hussein, Mostafa A., Abdel Aziz, Salah A., Abou-Salim, Mahrous A.

“…In continuation to our previous work, thiazolopyrimidines 2a–x were synthesized through intramolecular cyclization of 2-phenacylthio-dihydropyrimidine…”
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Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory-analgesic activities by Mohammed, Anber F., Abdel-Moty, Samia G., Hussein, Mostafa A., Abdel-Alim, Abdel-Alim M.

“…The present work describes the synthesis and evaluation of some new acetohydrazones, 1,3,4-oxadiazoles and 1,2,4-triazoles of 1,2,4-triazolo[1,5- a…”
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Synthesis and antimicrobial evaluation of some new thiazoline and thiazolidinone derivatives incorporating [1,2,4]triazolo[1,5-a]benzimidazole by Mahmoud, A, Salem, Ola, Abdel Moty, Samia, Abdel Alim, A

“…Two new series of 3-[2-(3,4-disubstituted-2,3-dihydrothiazol-2-ylidene)hydrazonopropylidenyl]-2-(methylthio)-3H-[1,2,4]triazolo[1,5-a]benzimidazole (6-29) and…”
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Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes by Maghraby, Mohammed T.-E., Abou-Ghadir, Ola M.F., Abdel-Moty, Samia G., Ali, Asmaa Y., Salem, Ola I.A.

“…[Display omitted] •Design and synthesis of novel dual COX-2 and 15-LOX benzimidazole-thiazole hybrids.•Potent COX-2 inhibition with high selectivity comparable…”
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Further insight into the dual COX-2 and 15-LOX anti-inflammatory activity of 1,3,4-thiadiazole-thiazolidinone hybrids: The contribution of the substituents at 5th positions is size dependent by Omar, Yasser M., Abdel-Moty, Samia G., Abdu-Allah, Hajjaj H.M.

“…[Display omitted] •Efficient synthesis of 1,3,4-thiadiazole-4-thiazolidinone hybrids modified at the 5th position of thiadiazole and/or thiazolidinone.•The in…”
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Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX by Omar, Yasser M., Abdu-Allah, Hajjaj H.M., Abdel-Moty, Samia G.

“…[Display omitted] •Synthesis of 1,3,4-thiadiazole-thiazolidinone hybrids and their alk/arylidene derivatives.•The potency and selectivity of these hybrids are…”
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Hybrids of 4-aminosalicylic acid with dual anti-mycobacterial and anti-inflammatory activities: Synthesis, biological evaluation, in silico investigation and structure-activity relationships exploration by Hassan, Ahmed M.M., Mohammed, Anber F., kumari, Jyothi, Sriram, Dharmarajan, Abdu-Allah, Hajjaj H.M., Abdel-Moty, Samia G.A.

“…•Synthesis and characterization of newly synthesized thirty-one hybrids of 4-aminosalicylic acid.•in vitro evaluation of antimycobacterial and…”
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Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives by Mohammed, Anber F., Andrei, Graciela, Hayallah, Alaa M., Abdel-Moty, Samia G., Snoeck, Robert, Simons, Claire

“…[Display omitted] A series of tricyclic penciclovir (PCV) and hydroxybutylguanine (HBG) derivatives have been prepared with enhanced lipophilicity following an…”
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Synthesis and biological activities of new substituted thiazoline-quinoline derivatives by Hussein, Mostafa, Kafafy, Abdel-Hamid, Abdel-Moty, Samia, Abou-Ghadir, Ola

“…5-Acyl-8-hydroxyquinoline-2-(3'-substituted-4'-aryl-2,3-dihydrothiazol-2'-ylidene)hydrazones, 5a-e to 10a-c, were prepared by the reaction of appropriate…”
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Synthesis of new 4,5-3(2H)pyridazinone derivatives and their cardiotonic, hypotensive, and platelet aggregation inhibition activities by Amin, Enas Nashaat, Abdel-Alim, Abdel-Alim M., Abdel-Moty, Samia G., El-Shorbagi, Abdel-Naser A., Abdel-Rahman, Mahran Sh

“…4,5-dihydro-3(2H)pyridazinones such as CI-914, CI-930 and pimobendan along with tetrahydropyridopyridazine (endralazine) and perhydropyridazinodiazepine…”
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Design and synthesis of novel 5-aminosalicylate (5-ASA)–4-thiazolinone hybrid derivatives with promising antiproliferative activity by Abdu-Allah, Hajjaj H.M., Abdel-Moty, Samia G., El-Awady, Raafat, El-Shorbagi, Abdel-Nasser A.

“…[Display omitted] Two privileged pharmacophores were assembled in one molecular frame involving 5-aminosalicylate and 4-thiazolinones that can be found in…”
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Design, synthesis and antiproliferative evaluation of lipidated 1,3-diaryl propenones and their cyclized pyrimidine derivatives as tubulin polymerization inhibitors by Ali, Fatma Elzahraa, Salem, Ola I.A., El-Mokhtar, Mohamed A., Aboraia, Ahmed S., Abdel-Moty, Samia G., Abdel-Aal, Abu-Baker M.

“…[Display omitted] •Sixteen new chalcones and their cyclized pyrimidine derivatives were synthesized.•The lipidated 4,6-diaryl pyrimidine-2-amine 19 exhibited…”
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Synthesis and Anti-Inflammatory Testing of Some New Compounds Incorporating 5-Aminosalicylic Acid (5-ASA) as Potential Prodrugs by Abdel-Alim Abdel-Alim Mohamed, EI-Shorbagi Abdel-Nasser Ahmed, Abdel-Moty Samia Galal, Abdel-Allah Hajjaj Hassan Mohamed

“…This work includes the synthesis of 15 final compounds (6a-h and 7b-h) as prod rugs of 5-ASA in the form of the acid itself, esters and amides linked by an…”
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STRUCTURE AND SYNTHESIS OF A NEW CHIRAL β-CARBOLINE FOUND IN CULTURED CELL CLUMPS OF RAUWOLFIA SERPENTINA AND RHAZYA STRICTA by KITAJIMA, Mariko, SHIRAKAWA, Seiichiro, ABDEL-MOTY, Samia G. A., TAKAYAMA, Hiromitsu, SAKAI, Shin-ichiro, AIMI, Norio, STOCKIGT, Joachim

“…The structure of a new chiral β-carboline derivative, Compound D, which was found during the chemical investigation of metabolites formed by cultured hybrid…”
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Synthesis and anti-inflammatory testing of some new compounds incorporating 5-aminosalicylic acid (5-ASA) as potential prodrugs by Abdel-Alim, Abdel-Alim Mohamed, El-Shorbagi, Abdel-Nasser Ahmed, Abdel-Moty, Samia Galal, Abdel-Allah, Hajjaj Hassan Mohamed

“…This work includes the synthesis of 15 final compounds (6a-h and7b-h) as prodrugs of 5-ASA in the form of the acid itself, esters and amides linked by an amide…”
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STRUCTURE AND SYNTHESIS OF A NEW CHIRAL [beta]-CARBOLINE FOUND IN CULTURED CELL CLUMPS OF RAUWOLFIA SERPENTINA AND RHAZYA STRICTA by KITAJIMA, Mariko, SHIRAKAWA, Seiichiro, G. A. ABDEL-MOTY, Samia, TAKAYAMA, Hiromitsu, SAKAI, Shin-ichiro, AIMI, Norio, STOCKIGT, Joachim

“…The structure of a new chiral β-carboline derivative, Compound D, which was found during the chemical investigation of metabolites formed by cultured hybrid…”
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Sinteza i biološko djelovanje novih supstituiranih derivata tiazolin-kinolina by HUSSEIN, MOSTAFA A., KAFAFY, ABDEL-HAMID N., ABDEL-MOTY, SAMIA G., ABOU-GHADIR, OLA MOHAMED F.

“…5-Acil-8-hidroksikinolin-2-(3'-supstituirani-4'-aril-2,3-dihidrotiazol-2'-ilid- ne)hidrazoni 5a-e do 10a-c pripravljeni su reakcijom odgovarajućih…”
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