Search Results - "Abdeen, Sanofar J"

Capillary mediated vitrification is a novel technique that enables storage of antibody critical reagents at ambient temperature: Impact on binding, structure, and laboratory sustainability by Shank-Retzlaff, Mary, Abdeen, Sanofar J., Bronsart, Laura, Cieslak, Alyssa N., Cruse, James K., Kinne, Adam S., Mohanty, Pravansu, Parmer, Elijah S., Radford, Shari, Bowsher, Ronald R.

“…Antibodies and antibody conjugates are essential components of life science research, but their inherent instability necessitates cold storage or…”
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Noncompetitive immunoassay optimized for pharmacokinetic assessments of biologically active efruxifermin by Kinne, Adam S., Tillman, Erik J., Abdeen, Sanofar J., Johnson, Derrick E., Parmer, Elijah S., Hurst, Jacob P., de Temple, Brittany, Rinker, Sherri, Rolph, Timothy P., Bowsher, Ronald R.

“…Efruxifermin (EFX) is a homodimeric human IgG1 Fc-FGF21 fusion protein undergoing investigation for treatment of liver fibrosis due to nonalcoholic…”
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FN3-based monobodies selective for the receptor binding domain of the SARS-CoV-2 spike protein by Miller, Christina J., McGinnis, Jennifer E., Martinez, Michael J., Wang, Guangli, Zhou, Jian, Simmons, Erica, Amet, Tohti, Abdeen, Sanofar J., Van Huysse, James W., Bowsher, Ronald R., Kay, Brian K.

“…•Monobodies were generated via phage-display to the SARS-CoV-2 spike protein.•Affinities of the monobodies for the RBD are estimated between 3 and 14 nM.•The…”
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Critical reagent inventory management system and web portal specifically optimized for supporting external clients by Feauto, Jessica A, Davis, Aleks, Delhaye, Richard C, Abdeen, Sanofar J, Gill, Hannah N, Colwell, Jamie E, Chiappetta, Michael, Clor, Emma E, Bowsher, Ronald R

“…High-quality critical reagents are essential for the establishment of robust ligand binding assays to support regulated bioanalysis. To ensure consistency in…”
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Peptide Inhibitors Targeting Clostridium difficile Toxins A and B by Abdeen, Sanofar J, Swett, Rebecca J, Feig, Andrew L

“…Clostridium difficile causes severe hospital-acquired antibiotic-associated diarrhea due to the activity of two large protein toxins. Current treatments suffer…”
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Generation of Affinity Purified Antibody Reagents for Specific Determination of Efruxifermin in Biological Matrices by Kinne, Adam S, Abdeen, Sanofar J, Parmer, Elijah S, Thystrup, Jennifer A, Tillman, Erik J, Rolph, Timothy P, Bowsher, Ronald R

“…Efruxifermin (EFX) is a novel Fc-fusion analog of human fibroblast growth factor 21 (FGF21), currently in clinical development as a potential treatment for…”
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Development of peptide inhibitors targeting Clostridium difficile toxins A/B and characterizing the regulatory role of a putative negative regulator TcdC in Clostridium difficile toxin gene expression by Abdeen, Sanofar J

“…Clostridium difficile infections cause one of the most common and vital hospitalacquired diseases often associated with broad-spectrum antibiotic usage. TcdA…”
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Development of peptide inhibitors targeting Clostridium difficile toxins A/B and characterizing the regulatory role of a putative negative regulator TcdC in Clostridium difficile toxin gene expression by Abdeen, Sanofar J

“…Clostridium difficile infections cause one of the most common and vital hospitalacquired diseases often associated with broad-spectrum antibiotic usage. TcdA…”
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