Search Results - "Abdallah, R S"
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Tobacco exposure as a major modifier of oncologic outcomes in human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma
Published in BMC cancer (23-09-2020)“…The incidence of oropharyngeal squamous cell carcinoma (OPSCC) in the US is rapidly increasing, driven largely by the epidemic of human papillomavirus…”
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Association of Body Composition With Survival and Locoregional Control of Radiotherapy-Treated Head and Neck Squamous Cell Carcinoma
Published in JAMA oncology (01-06-2016)“…Major weight loss is common in patients with head and neck squamous cell carcinoma (HNSCC) who undergo radiotherapy (RT). How baseline and posttreatment body…”
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Exploring Applications of Radiomics in Magnetic Resonance Imaging of Head and Neck Cancer: A Systematic Review
Published in Frontiers in oncology (14-05-2018)“…Radiomics has been widely investigated for non-invasive acquisition of quantitative textural information from anatomic structures. While the vast majority of…”
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A PET Radiomics Model to Predict Refractory Mediastinal Hodgkin Lymphoma
Published in Scientific reports (04-02-2019)“…First-order radiomic features, such as metabolic tumor volume (MTV) and total lesion glycolysis (TLG), are associated with disease progression in early-stage…”
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Optimal Treatment Selection in Sequential Systemic and Locoregional Therapy of Oropharyngeal Squamous Carcinomas: Deep Q-Learning With a Patient-Physician Digital Twin Dyad
Published in Journal of medical Internet research (20-04-2022)“…Currently, selection of patients for sequential versus concurrent chemotherapy and radiation regimens lacks evidentiary support and it is based on locally…”
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PleThora: Pleural effusion and thoracic cavity segmentations in diseased lungs for benchmarking chest CT processing pipelines
Published in Medical physics (Lancaster) (01-11-2020)“…This manuscript describes a dataset of thoracic cavity segmentations and discrete pleural effusion segmentations we have annotated on 402 computed tomography…”
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Oropharyngeal cancer patient stratification using random forest based-learning over high-dimensional radiomic features
Published in Scientific reports (07-07-2021)“…To improve risk prediction for oropharyngeal cancer (OPC) patients using cluster analysis on the radiomic features extracted from pre-treatment Computed…”
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Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer
Published in British journal of cancer (11-05-2021)“…Background Lactate dehydrogenase (LDH) is a critical metabolic enzyme. LDH A ( LDHA ) overexpression is a hallmark of aggressive malignancies and has been…”
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Investigation of radiomic signatures for local recurrence using primary tumor texture analysis in oropharyngeal head and neck cancer patients
Published in Scientific reports (24-01-2018)“…Radiomics is one such “big data” approach that applies advanced image refining/data characterization algorithms to generate imaging features that can…”
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A High-throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma
Published in The journal of clinical endocrinology and metabolism (01-10-2021)“…Despite the use of aggressive multimodality treatment, most anaplastic thyroid carcinoma (ATC) patients die within a year of diagnosis. Although the…”
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Automatic registration of 2D MR cine images for swallowing motion estimation
Published in PloS one (11-02-2020)“…To automate the estimation of swallowing motion from 2D MR cine images using deformable registration for future applications of personalized margin reduction…”
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An algorithm for thoracic re-irradiation using biologically effective dose: a common language on how to treat in a "no-treat zone"
Published in Radiation oncology (London, England) (06-01-2022)“…Re-irradiation (re-RT) is a technically challenging task for which few standardized approaches exist. This is in part due to the lack of a common platform to…”
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Intravoxel incoherent motion imaging kinetics during chemoradiotherapy for human papillomavirus-associated squamous cell carcinoma of the oropharynx: preliminary results from a prospective pilot study
Published in NMR in biomedicine (01-12-2015)“…This study aims to identify the temporal kinetics of intravoxel incoherent motion (IVIM) MRI in patients with human papillomavirus‐associated (HPV+)…”
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Biomechanical modeling of radiation dose-induced volumetric changes of the parotid glands for deformable image registration
Published in Physics in medicine & biology (31-08-2020)“…Early animal studies suggest that parotid gland (PG) toxicity prediction could be improved by an accurate estimation of the radiation dose to sub-regions of…”
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Radiation therapy dose is associated with improved survival for unresected anaplastic thyroid carcinoma: Outcomes from the National Cancer Data Base
Published in Cancer (01-05-2017)“…BACKGROUND The outcomes of patients with unresected anaplastic thyroid carcinoma (ATC) from the National Cancer Data Base (NCDB) were assessed, and potential…”
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Quality assurance assessment of diagnostic and radiation therapy-simulation CT image registration for head and neck radiation therapy: anatomic region of interest-based comparison of rigid and deformable algorithms
Published in Radiology (01-03-2015)“…To develop a quality assurance (QA) workflow by using a robust, curated, manually segmented anatomic region-of-interest (ROI) library as a benchmark for…”
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Changes in Apparent Diffusion Coefficient (ADC) in Serial Weekly MRI during Radiotherapy in Patients with Head and Neck Cancer: Results from the PREDICT-HN Study
Published in Current oncology (Toronto) (31-08-2022)“…Background: The PREDICT-HN study aimed to systematically assess the kinetics of imaging MR biomarkers during head and neck radiotherapy. Methods: Patients with…”
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Large scale crowdsourced radiotherapy segmentations across a variety of cancer anatomic sites
Published in Scientific data (22-03-2023)“…Clinician generated segmentation of tumor and healthy tissue regions of interest (ROIs) on medical images is crucial for radiotherapy. However, interobserver…”
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Late radiation-associated dysphagia (late-RAD) with lower cranial neuropathy after oropharyngeal radiotherapy: A preliminary dosimetric comparison
Published in Oral oncology (01-08-2014)“…Summary Background and objectives Late radiation-associated dysphagia (late-RAD) is a rare delayed toxicity, in oropharyngeal cancer (OPC) survivors…”
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Muscle and adipose tissue segmentations at the third cervical vertebral level in patients with head and neck cancer
Published in Scientific data (02-08-2022)“…The accurate determination of sarcopenia is critical for disease management in patients with head and neck cancer (HNC). Quantitative determination of…”
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