Search Results - "Abd Elhadi, Suaad"
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α-Synuclein Translocates to the Nucleus to Activate Retinoic-Acid-Dependent Gene Transcription
Published in iScience (27-03-2020)“…α-Synuclein (α-Syn) protein is implicated in the pathogenesis of Parkinson disease (PD). It is primarily cytosolic and interacts with cell membranes. α-Syn…”
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α‐Synuclein in blood cells differentiates Parkinson’s disease from healthy controls
Published in Annals of clinical and translational neurology (01-12-2019)“…Objective To determine whether blood cells expressed α‐Syn can differentiate Parkinson’s disease (PD) from healthy controls (HC). Methods The concentrations of…”
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3
A role for α-Synuclein in axon growth and its implications in corticostriatal glutamatergic plasticity in Parkinson's disease
Published in Molecular neurodegeneration (30-03-2020)“…α-Synuclein (α-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). α-Syn has been shown to associate with membranes and bind acidic…”
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4
Safety and Tolerability, Dose-Escalating, Double-Blind Trial of Oral Mannitol in Parkinson's Disease
Published in Frontiers in neurology (03-01-2022)“…Mannitol, a natural alcoholic-sugar, was recently suggested as a potential disease-modifying agent in Parkinson's disease. In animal models of the disease,…”
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α-Synuclein facilitates endocytosis by elevating the steady-state levels of phosphatidylinositol 4,5-bisphosphate
Published in The Journal of biological chemistry (25-12-2020)“…α-Synuclein (α-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). It is an intrinsically disordered protein that binds acidic…”
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Total α-synuclein levels in human blood cells, CSF, and saliva determined by a lipid-ELISA
Published in Analytical and bioanalytical chemistry (01-11-2016)“…The validity of α-synuclein (α-Syn) as a biomarker for Parkinson’s disease (PD) is still under investigation. Conventional methods for capture and quantitation…”
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Total and Proteinase K-Resistant α-Synuclein Levels in Erythrocytes, Determined by their Ability to Bind Phospholipids, Associate with Parkinson’s Disease
Published in Scientific reports (11-06-2015)“…A marker for diagnosis of Parkinson’s disease (PD), which reflects on the occurrence of peripheral pathogenic mechanisms, would potentially improve therapy…”
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8
A role for [alpha]-Synuclein in axon growth and its implications in corticostriatal glutamatergic plasticity in Parkinson's disease
Published in Molecular neurodegeneration (30-03-2020)“…Background [alpha]-Synuclein ([alpha]-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). [alpha]-Syn has been shown to associate…”
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Journal Article -
9
Total [alpha]-synuclein levels in human blood cells, CSF, and saliva determined by a lipid-ELISA
Published in Analytical and bioanalytical chemistry (01-11-2016)“…The validity of [alpha]-synuclein ([alpha]-Syn) as a biomarker for Parkinson's disease (PD) is still under investigation. Conventional methods for capture and…”
Get full text
Journal Article -
10
α-Synuclein facilitates endocytosis by elevating the steady-state levels of phosphatidylinositol 4,5-bisphosphate
Published in The Journal of biological chemistry (25-12-2020)“…α-Synuclein (α-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). It is an intrinsically disordered protein that binds acidic…”
Get full text
Journal Article -
11
Total and Proteinase K-Resistant [alpha]-Synuclein Levels in Erythrocytes, Determined by their Ability to Bind Phospholipids, Associate with Parkinson's Disease
Published in Scientific reports (01-06-2015)“…A marker for diagnosis of Parkinson's disease (PD), which reflects on the occurrence of peripheral pathogenic mechanisms, would potentially improve therapy…”
Get full text
Journal Article