Search Results - "Abbink, Peter"

SARS-CoV-2 infection protects against rechallenge in rhesus macaques by Chandrashekar, Abishek, Liu, Jinyan, Martinot, Amanda J, McMahan, Katherine, Mercado, Noe B, Peter, Lauren, Tostanoski, Lisa H, Yu, Jingyou, Maliga, Zoltan, Nekorchuk, Michael, Busman-Sahay, Kathleen, Terry, Margaret, Wrijil, Linda M, Ducat, Sarah, Martinez, David R, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S, Slein, Matthew D, Pessaint, Laurent, Van Ry, Alex, Greenhouse, Jack, Taylor, Tammy, Blade, Kelvin, Cook, Anthony, Finneyfrock, Brad, Brown, Renita, Teow, Elyse, Velasco, Jason, Zahn, Roland, Wegmann, Frank, Abbink, Peter, Bondzie, Esther A, Dagotto, Gabriel, Gebre, Makda S, He, Xuan, Jacob-Dolan, Catherine, Kordana, Nicole, Li, Zhenfeng, Lifton, Michelle A, Mahrokhian, Shant H, Maxfield, Lori F, Nityanandam, Ramya, Nkolola, Joseph P, Schmidt, Aaron G, Miller, Andrew D, Baric, Ralph S, Alter, Galit, Sorger, Peter K, Estes, Jacob D, Andersen, Hanne, Lewis, Mark G, Barouch, Dan H

“…An understanding of protective immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for vaccine and public health strategies…”
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Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys by Borducchi, Erica N., Liu, Jinyan, Nkolola, Joseph P., Cadena, Anthony M., Yu, Wen-Han, Fischinger, Stephanie, Broge, Thomas, Abbink, Peter, Mercado, Noe B., Chandrashekar, Abishek, Jetton, David, Peter, Lauren, McMahan, Katherine, Moseley, Edward T., Bekerman, Elena, Hesselgesser, Joseph, Li, Wenjun, Lewis, Mark G., Alter, Galit, Geleziunas, Romas, Barouch, Dan H.

“…The latent viral reservoir is the critical barrier for the development of a cure for HIV-1 infection. Previous studies have shown direct antiviral activity of…”
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Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys by Abbink, Peter, Larocca, Rafael A., De La Barrera, Rafael A., Bricault, Christine A., Moseley, Edward T., Boyd, Michael, Kirilova, Marinela, Li, Zhenfeng, Ng'ang'a, David, Nanayakkara, Ovini, Nityanandam, Ramya, Mercado, Noe B., Borducchi, Erica N., Agarwal, Arshi, Brinkman, Amanda L., Cabral, Crystal, Chandrashekar, Abishek, Giglio, Patricia B., Jetton, David, Jimenez, Jessica, Lee, Benjamin C., Mojta, Shanell, Molloy, Katherine, Shetty, Mayuri, Neubauer, George H., Stephenson, Kathryn E., Peron, Jean Pierre S., de A. Zanotto, Paolo M., Misamore, Johnathan, Finneyfrock, Brad, Lewis, Mark G., Alter, Galit, Modjarrad, Kayvon, Jarman, Richard G., Eckels, Kenneth H., Michael, Nelson L., Thomas, Stephen J., Barouch, Dan H.

“…Zika virus (ZIKV) is responsible for a major ongoing epidemic in the Americas and has been causally associated with fetal microcephaly. The development of a…”
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Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys by Aid, Malika, Abbink, Peter, Larocca, Rafael A., Boyd, Michael, Nityanandam, Ramya, Nanayakkara, Ovini, Martinot, Amanda J., Moseley, Edward T., Blass, Eryn, Borducchi, Erica N., Chandrashekar, Abishek, Brinkman, Amanda L., Molloy, Katherine, Jetton, David, Tartaglia, Lawrence J., Liu, Jinyan, Best, Katharine, Perelson, Alan S., De La Barrera, Rafael A., Lewis, Mark G., Barouch, Dan H.

“…Zika virus (ZIKV) is associated with severe neuropathology in neonates as well as Guillain-Barré syndrome and other neurologic disorders in adults. Prolonged…”
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Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers by Pauthner, Matthias G., Nkolola, Joseph P., Havenar-Daughton, Colin, Murrell, Ben, Reiss, Samantha M., Bastidas, Raiza, Prévost, Jérémie, Nedellec, Rebecca, von Bredow, Benjamin, Abbink, Peter, Cottrell, Christopher A., Kulp, Daniel W., Tokatlian, Talar, Nogal, Bartek, Bianchi, Matteo, Li, Hui, Lee, Jeong Hyun, Butera, Salvatore T., Evans, David T., Hangartner, Lars, Finzi, Andrés, Wilson, Ian A., Wyatt, Richard T., Irvine, Darrell J., Schief, William R., Ward, Andrew B., Sanders, Rogier W., Crotty, Shane, Shaw, George M., Barouch, Dan H., Burton, Dennis R.

“…Passive administration of HIV neutralizing antibodies (nAbs) can protect macaques from hard-to-neutralize (tier 2) chimeric simian-human immunodeficiency virus…”
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Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques by McCracken, Michael K, Gromowski, Gregory D, Friberg, Heather L, Lin, Xiaoxu, Abbink, Peter, De La Barrera, Rafael, Eckles, Kenneth H, Garver, Lindsey S, Boyd, Michael, Jetton, David, Barouch, Dan H, Wise, Matthew C, Lewis, Bridget S, Currier, Jeffrey R, Modjarrad, Kayvon, Milazzo, Mark, Liu, Michelle, Mullins, Anna B, Putnak, J Robert, Michael, Nelson L, Jarman, Richard G, Thomas, Stephen J

“…Studies have demonstrated cross-reactivity of anti-dengue virus (DENV) antibodies in human sera against Zika virus (ZIKV), promoting increased ZIKV infection…”
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Protective Efficacy of a Global HIV-1 Mosaic Vaccine against Heterologous SHIV Challenges in Rhesus Monkeys by Barouch, Dan H., Stephenson, Kathryn E., Borducchi, Erica N., Smith, Kaitlin, Stanley, Kelly, McNally, Anna G., Liu, Jinyan, Abbink, Peter, Maxfield, Lori F., Seaman, Michael S., Dugast, Anne-Sophie, Alter, Galit, Ferguson, Melissa, Li, Wenjun, Earl, Patricia L., Moss, Bernard, Giorgi, Elena E., Szinger, James J., Eller, Leigh Anne, Billings, Erik A., Rao, Mangala, Tovanabutra, Sodsai, Sanders-Buell, Eric, Weijtens, Mo, Pau, Maria G., Schuitemaker, Hanneke, Robb, Merlin L., Kim, Jerome H., Korber, Bette T., Michael, Nelson L.

“…The global diversity of HIV-1 represents a critical challenge facing HIV-1 vaccine development. HIV-1 mosaic antigens are bioinformatically optimized…”
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A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti-Zika Virus Vaccine by Salisch, Nadine C, Stephenson, Kathryn E, Williams, Kristi, Cox, Freek, van der Fits, Leslie, Heerwegh, Dirk, Truyers, Carla, Habets, Marrit N, Kanjilal, Diane G, Larocca, Rafael A, Abbink, Peter, Liu, Jinyan, Peter, Lauren, Fierro, Carlos, De La Barrera, Rafael A, Modjarrad, Kayvon, Zahn, Roland C, Hendriks, Jenny, Cahill, Conor P, Leyssen, Maarten, Douoguih, Macaya, van Hoof, Johan, Schuitemaker, Hanneke, Barouch, Dan H

“…Zika virus (ZIKV) may cause severe congenital disease after maternal-fetal transmission. No vaccine is currently available. To assess the safety and…”
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Durability and correlates of vaccine protection against Zika virus in rhesus monkeys by Abbink, Peter, Larocca, Rafael A, Visitsunthorn, Kittipos, Boyd, Michael, De La Barrera, Rafael A, Gromowski, Gregory D, Kirilova, Marinela, Peterson, Rebecca, Li, Zhenfeng, Nanayakkara, Ovini, Nityanandam, Ramya, Mercado, Noe B, Borducchi, Erica N, Chandrashekar, Abishek, Jetton, David, Mojta, Shanell, Gandhi, Priya, LeSuer, Jake, Khatiwada, Shreeya, Lewis, Mark G, Modjarrad, Kayvon, Jarman, Richard G, Eckels, Kenneth H, Thomas, Stephen J, Michael, Nelson L, Barouch, Dan H

“…An effective Zika virus (ZIKV) vaccine will require long-term durable protection. Several ZIKV vaccine candidates have demonstrated protective efficacy in…”
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Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys by Barouch, Dan H., Liu, Jinyan, Li, Hualin, Maxfield, Lori F., Abbink, Peter, Lynch, Diana M., Iampietro, M. Justin, SanMiguel, Adam, Seaman, Michael S., Ferrari, Guido, Forthal, Donald N., Ourmanov, Ilnour, Hirsch, Vanessa M., Carville, Angela, Mansfield, Keith G., Stablein, Donald, Pau, Maria G., Schuitemaker, Hanneke, Sadoff, Jerald C., Billings, Erik A., Rao, Mangala, Robb, Merlin L., Kim, Jerome H., Marovich, Mary A., Goudsmit, Jaap, Michael, Nelson L.

“…Protective efficacy of novel vaccine candidates in rhesus monkeys opens new paths for the development of an HIV-1 vaccine. Vaccines protect against virulent…”
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Adenoviral vector type 26 encoding Zika virus (ZIKV) M-Env antigen induces humoral and cellular immune responses and protects mice and nonhuman primates against ZIKV challenge by Cox, Freek, van der Fits, Leslie, Abbink, Peter, Larocca, Rafael A, van Huizen, Ella, Saeland, Eirikur, Verhagen, Janneke, Peterson, Rebecca, Tolboom, Jeroen, Kaufmann, Baerbel, Schuitemaker, Hanneke, Barouch, Dan H, Zahn, Roland

“…In 2015, there was a large outbreak of Zika virus (ZIKV) in Brazil. Despite its relatively mild impact on healthy adults, ZIKV infection during pregnancy has…”
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Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors by López-Camacho, César, Abbink, Peter, Larocca, Rafael A., Dejnirattisai, Wanwisa, Boyd, Michael, Badamchi-Zadeh, Alex, Wallace, Zoë R., Doig, Jennifer, Velazquez, Ricardo Sanchez, Neto, Roberto Dias Lins, Coelho, Danilo F., Kim, Young Chan, Donald, Claire L., Owsianka, Ania, De Lorenzo, Giuditta, Kohl, Alain, Gilbert, Sarah C., Dorrell, Lucy, Mongkolsapaya, Juthathip, Patel, Arvind H., Screaton, Gavin R., Barouch, Dan H., Hill, Adrian V. S., Reyes-Sandoval, Arturo

“…Zika virus (ZIKV) emerged on a global scale and no licensed vaccine ensures long-lasting anti-ZIKV immunity. Here we report the design and comparative…”
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Prevention of SIVmac251 reservoir seeding in rhesus monkeys by early antiretroviral therapy by Whitney, James B., Lim, So-Yon, Osuna, Christa E., Kublin, Jessica L., Chen, Elsa, Yoon, Gyeol, Liu, Po-Ting, Abbink, Peter, Borducci, Erica N., Hill, Alison, Lewis, Mark G., Geleziunas, Romas, Robb, Merlin L., Michael, Nelson L., Barouch, Dan H.

“…The precise time when the viral reservoir is seeded during acute HIV-1 infection remains unclear. We previously demonstrated that the viral reservoir was…”
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Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys by Barouch, Dan H, O'Brien, Kara L, Simmons, Nathaniel L, King, Sharon L, Abbink, Peter, Maxfield, Lori F, Sun, Ying-Hua, La Porte, Annalena, Riggs, Ambryice M, Lynch, Diana M, Clark, Sarah L, Backus, Katherine, Perry, James R, Seaman, Michael S, Carville, Angela, Mansfield, Keith G, Szinger, James J, Fischer, Will, Muldoon, Mark, Korber, Bette

“…The worldwide diversity of HIV-1 presents an unprecedented challenge for vaccine development. Antigens derived from natural HIV-1 sequences have elicited only…”
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Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques by Cadena, Anthony M., Ventura, John D., Abbink, Peter, Borducchi, Erica N., Tuyishime, Hubert, Mercado, Noe B., Walker-Sperling, Victoria, Siamatu, Mazuba, Liu, Po-Ting, Chandrashekar, Abishek, Nkolola, Joseph P., McMahan, Katherine, Kordana, Nicole, Hamza, Venous, Bondzie, Esther A., Fray, Emily, Kumar, Mithra, Fischinger, Stephanie, Shin, Sally A., Lewis, Mark G., Siliciano, Robert F., Alter, Galit, Barouch, Dan H.

“…The establishment of a long-lived viral reservoir is the key obstacle for achieving an HIV-1 cure. However, the anatomic, virologic, and immunologic features…”
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Adenovirus Serotype 26 Utilizes CD46 as a Primary Cellular Receptor and Only Transiently Activates T Lymphocytes following Vaccination of Rhesus Monkeys by Li, Hualin, Rhee, Elizabeth G, Masek-Hammerman, Katherine, Teigler, Jeffrey E, Abbink, Peter, Barouch, Dan H

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Comparative Seroprevalence and Immunogenicity of Six Rare Serotype Recombinant Adenovirus Vaccine Vectors from Subgroups B and D by ABBINK, Peter, LEMCKERT, Angelique A. C, O'BRIEN, Kara L, CARVILLE, Angela, MANSFIELD, Keith G, GOUDSMIT, Jaap, HAVENGA, Menzo J. E, BAROUCH, Dan H, EWALD, Bonnie A, LYNCH, Diana M, DENHOLTZ, Matthew, SMITS, Shirley, HOLTERMAN, Lennart, DAMEN, Irma, VOGELS, Ronald, THORNER, Anna R

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First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1 by Stephenson, Kathryn E, Keefer, Michael C, Bunce, Catherine A, Frances, Doreen, Abbink, Peter, Maxfield, Lori F, Neubauer, George H, Nkolola, Joseph, Peter, Lauren, Lane, Christopher, Park, Harriet, Verlinde, Carl, Lombardo, Angela, Yallop, Christopher, Havenga, Menzo, Fast, Patricia, Treanor, John, Barouch, Dan H

“…Live, attenuated viral vectors that express HIV-1 antigens are being investigated as an approach to generating durable immune responses against HIV-1 in…”
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Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation by Liu, Po-Ting, Keele, Brandon F., Abbink, Peter, Mercado, Noe B., Liu, Jinyan, Bondzie, Esther A., Chandrashekar, Abishek, Borducchi, Erica N., Hesselgesser, Joseph, Mish, Michael, Chin, Gregory, Bekerman, Elena, Geleziunas, Romas, Barouch, Dan H.

“…Viral rebound following antiretroviral therapy (ART) discontinuation in HIV-1-infected individuals is believed to originate from a small pool of CD4+ T cells…”
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Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo by Tartaglia, Lawrence J, Badamchi-Zadeh, Alexander, Abbink, Peter, Blass, Eryn, Aid, Malika, Gebre, Makda S, Li, Zhenfeng, Pastores, Kevin Clyde, Trott, Sebastien, Gupte, Siddhant, Larocca, Rafael A, Barouch, Dan H

“…Adenoviral vectors have shown significant promise as vaccine delivery vectors due to their ability to elicit both innate and adaptive immune responses…”
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