Search Results - "Abashkin, Viktar"
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Dendrimers Show Promise for siRNA and microRNA Therapeutics
Published in Pharmaceutics (08-08-2018)“…The lack of an appropriate intracellular delivery system for therapeutic nucleic acids (TNAs) is a major problem in molecular biology, biotechnology, and…”
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2
Silver Nanoparticles Modified by Carbosilane Dendrons and PEG as Delivery Vectors of Small Interfering RNA
Published in International journal of molecular sciences (03-01-2023)“…The fact that cancer is one of the leading causes of death requires researchers to create new systems of effective treatment for malignant tumors. One…”
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3
PAMAM-Calix-Dendrimers: Second Generation Synthesis, Fluorescent Properties and Catecholamines Binding
Published in Pharmaceutics (01-12-2022)“…A convenient method for the synthesis of the second generation of PAMAM dendrimers based on a -butylthiacalix[4]arene core in , and conformations was…”
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4
Silver Nanoparticles Surface-Modified with Carbosilane Dendrons as Carriers of Anticancer siRNA
Published in International journal of molecular sciences (30-06-2020)“…Gene therapy is a promising approach in cancer treatment; however, current methods have a number of limitations mainly due to the difficulty in delivering…”
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Prospects of Cationic Carbosilane Dendronized Gold Nanoparticles as Non-viral Vectors for Delivery of Anticancer siRNAs siBCL-xL and siMCL-1
Published in Pharmaceutics (24-09-2021)“…Cancer is one of the most important problems of modern medicine. At the present time, gene therapy has been developed against cancer, which includes the…”
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Hybrid metal-organic nanoflowers and their application in biotechnology and medicine
Published in Colloids and surfaces, B, Biointerfaces (01-10-2019)“…[Display omitted] •Nanoflowers are new nanostructures.•They have applications in catalysis.•Nanoflowers can be used as biosensors.•They can be drug carriers,…”
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Recent advances in multifunctional dendrimer‐based complexes for cancer treatment
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-03-2024)“…The application of nanotechnology in biological and medical fields have resulted in the creation of new devices, supramolecular systems, structures, complexes,…”
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Transferrin-Conjugated Manganese Dioxide/Semiconducting Polymer Hybrid Nanoparticles for Targeted Dual-Model Imaging of Orthotopic Glioblastoma
Published in ACS applied polymer materials (09-06-2023)“…Glioblastoma is one of the important diseases that threaten human health, while the early diagnosis of glioblastoma remains a great challenge. We herein report…”
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Ultrasonic Formation of Fe3O4-Reduced Graphene Oxide-Salicylic Acid Nanoparticles with Switchable Antioxidant Function
Published in ACS biomaterials science & engineering (14-03-2022)Get full text
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PAMAM-Calix-Dendrimers: Third Generation Synthesis and Impact of Generation and Macrocyclic Core Conformation on Hemotoxicity and Calf Thymus DNA Binding
Published in Pharmaceutics (27-10-2024)“…Background/Objectives: Current promising treatments for many diseases are based on the use of therapeutic nucleic acids, including DNA. However, the list of…”
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Effect of PEGylation on the biological properties of cationic carbosilane dendronized gold nanoparticles
Published in International journal of pharmaceutics (05-01-2020)“…[Display omitted] •Heterofunctionalized gold nanoparticles (AuNP) are easily obtained in a one pot reaction.•Dendron/PEG ratio and dendron generation are very…”
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Immunoreactivity changes of human serum albumin and alpha-1-microglobulin induced by their interaction with dendrimers
Published in Colloids and surfaces, B, Biointerfaces (01-07-2019)“…[Display omitted] •In equimolar complexes all dendrimers had no effect on immunoreactivity of proteins.•Anionic dendrimers had no effect on immunoreactivity of…”
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Ultrasonic Formation of Fe 3 O 4 -Reduced Graphene Oxide-Salicylic Acid Nanoparticles with Switchable Antioxidant Function
Published in ACS biomaterials science & engineering (14-03-2022)“…We demonstrate a single-step ultrasonic in situ complexation of salicylic acid during the growth of Fe O -reduced graphene oxide nanoparticles (∼10 nm) to…”
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14
Activation of Ibuprofen via Ultrasonic Complexation with Silver in N‑Doped Oxidized Graphene Nanoparticles for Microwave Chemotherapy of Cervix Tumor Tissues
Published in ACS biomaterials science & engineering (09-01-2023)“…An ultrasonic method (20 kHz) is introduced to activate pristine ibuprofen organic molecular crystals via complexation with silver in nitrogen-doped oxidized…”
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15
Nanoparticle corona for proteins: mechanisms of interaction between dendrimers and proteins
Published in Colloids and surfaces, B, Biointerfaces (01-10-2015)“…[Display omitted] •Dendrimers formed ‘nanoparticle corona’ surrounding proteins.•‘Nanoparticle corona’ had no impact on rigid proteins.•Dendrimers effect on…”
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Differences between Cu- and Fe–Cu nanoflowers in their interactions with fluorescent probes ANS and Fura-2 and proteins albumin and thrombin
Published in Polymer bulletin (Berlin, Germany) (01-07-2022)“…Among nanomaterials, we can now distinguish a special class called nanoflowers (NFs). These new nanostructures have aroused the interest of scientists due to…”
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Comparison of the effects of dendrimer, micelle and silver nanoparticles on phospholipase A2 structure
Published in Journal of biotechnology (10-04-2021)“…[Display omitted] •'Hard' and 'soft' nanoparticles differently affected phospholipase A2.•'Soft' nanoparticles formed aggregates/micelles with protein.•'Hard'…”
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Role of cationic carbosilane dendrons and metallic core of functionalized gold nanoparticles in their interaction with human serum albumin
Published in International journal of biological macromolecules (15-10-2018)“…Functionalization of gold nanoparticles by different chemical groups is an important issue regarding the biomedical applications of such particles. Therefore…”
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Ruthenium dendrimers against acute promyelocytic leukemia: in vitro studies on HL-60 cells
Published in Future medicinal chemistry (01-07-2019)“…Coordination of ruthenium arene fragments on carbosilane dendrimers' surface greatly increases their antitumor properties. Newly synthetized ruthenium…”
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Binding of poly(amidoamine), carbosilane, phosphorus and hybrid dendrimers to thrombin—Constants and mechanisms
Published in Colloids and surfaces, B, Biointerfaces (01-07-2017)“…[Display omitted] •Dendrimers rearranged thrombin structure.•Flexible dendrimers increased unstructured state of thrombin.•Rigid dendrimers increased a number…”
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