Search Results - "Abarikwu, Sunny O"

Atrazine: cytotoxicity, oxidative stress, apoptosis, testicular effects and chemopreventive Interventions by Abarikwu, Sunny O., Ezim, Ogechukwu E., Ikeji, Cynthia N., Farombi, Ebenezer O.

“…Atrazine (ATZ) is an environmental pollutant that interferes with several aspects of mammalian cellular processes including germ cell development,…”
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Changes in Sperm Characteristics and Induction of Oxidative Stress in the Testis and Epididymis of Experimental Rats by a Herbicide, Atrazine by Abarikwu, Sunny O, Adesiyan, Adebukola C, Oyeloja, Titilola O, Oyeyemi, Matthew O, Farombi, Ebenezer O

“…To study the effects of atrazine on reproductive functions and testicular and epididymal antioxidant defense, rats were exposed to 0, 120, or 200 mg/kg body…”
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Rutin ameliorates oxidative stress and preserves hepatic and renal functions following exposure to cadmium and ethanol by Abarikwu, Sunny O., Njoku, Rex-Clovis, Lawrence, Chiamaka J., Charles, Iniobong A., Ikewuchi, Jude C.

“…Context: Rutin (RUT) is an antioxidant flavonoid with well-known metal chelating potentials. Objective: This study was designed to evaluate the protective…”
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4-Hydroxynonenal Induces Mitochondrial-Mediated Apoptosis and Oxidative Stress in SH-SY5Y Human Neuronal Cells by Abarikwu, Sunny O., Pant, Aditya B., Farombi, Ebenezer O.

“…:  Excessive and sustained increases in oxidative stress and apoptosis have been implicated in the pathogenesis of many diseases. In this study, we…”
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Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophages by combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK by Abarikwu, Sunny O.

“…Kolaviron (Kol-v), an important component of Garcinia kola seed has a variety of biologic activities, including anti-inflammatory properties. We tested the…”
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Evaluation of the protective effects of quercetin and gallic acid against oxidative toxicity in rat’s kidney and HEK-293 cells by Abarikwu, Sunny O., Simple, Godwin, Onuoha, Samuel Chimezie, Mokwenye, Ifeoma, Ayogu, Jean-Frances

“…[Display omitted] •Gallic acid has better antioxidant protective effect than quercetin in vivo.•Quercetin has better antioxidant protective effect than gallic…”
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Curcumin protects against gallic acid-induced oxidative stress, suppression of glutathione antioxidant defenses, hepatic and renal damage in rats by Abarikwu, Sunny O., Durojaiye, Mojisola, Alabi, Adenike, Asonye, Bede, Akiri, Oghenetega

“…Curcumin (Cur) and gallic acid (Gal) are major food additives. Cur has well-known antioxidant properties, whereas Gal has both antioxidant and pro-oxidant…”
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Influence of triazines and lipopolysaccharide coexposure on inflammatory response and histopathological changes in the testis and liver of BalB/c mice by Abarikwu, Sunny O., Mgbudom-Okah, Chidimma J., Ndufeiya-Kumasi, Lauritta C., Monye, Vivian E., Aruoren, Oke, Ezim, Ogechukwu E., Omeodu, Stephen I., Charles, Iniobong A.

“…Triazines are environmental active chemicals that have been reported to alter the inflammatory status of the gonads. We tested the anti-inflammatory effect of…”
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Plants in the management of male infertility by Abarikwu, Sunny O., Onuah, Chigozie Linda, Singh, Shio Kumar

“…This review attempts to collate existing data and provide the perspectives for future studies on the effects of plants on the male gonads. For many of these…”
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COVID‐19 vaccinations: The unknowns, challenges, and hopes by Mohamed, Kawthar, Rzymski, Piotr, Islam, Md Shahidul, Makuku, Rangarirai, Mushtaq, Ayesha, Khan, Amjad, Ivanovska, Mariya, Makka, Sara A., Hashem, Fareeda, Marquez, Leander, Cseprekal, Orsolya, Filgueiras, Igor Salerno, Fonseca, Dennyson Leandro M., Mickael, Essouma, Ling, Irene, Arero, Amanuel Godana, Cuschieri, Sarah, Minakova, Kseniia, Rodríguez‐Román, Eduardo, Abarikwu, Sunny O., Faten, Attig‐Bahar, Grancini, Giulia, Cabral‐Marques, Otavio, Rezaei, Nima

“…The entire world has been suffering from the coronavirus disease 2019 (COVID‐19) pandemic since March 11, 2020. More than a year later, the COVID‐19…”
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Fluted pumpkin seeds protect the spermatogenesis score index and testicular histology of caffeine treated rats by Ezim, Ogechukwu E., Abarikwu, Sunny O.

“…The present study was designed to evaluate the protective effect of fluted pumpkin seeds (FPS) against caffeine (CAFF) induced testicular toxicity in rats…”
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Borderless collaboration is needed for COVID-19-A disease that knows no borders by Mohamed, Kawthar, Rodríguez-Román, Eduardo, Rahmani, Farzaneh, Zhang, Hongbo, Ivanovska, Mariya, Makka, Sara A, Joya, Musa, Makuku, Rangarirai, Islam, Md Shahidul, Radwan, Nesrine, Rahmah, Laila, Goda, Rayan, Abarikwu, Sunny O, Shaw, Mujtaba, Zoghi, Samaneh, Irtsyan, Sevan, Ling, Irene, Cseprekal, Orsolya, Faten, Attig-Bahar, Hazar Sayar, Esra, Soloukey, Chagajeg, Grancini, Giulia, Rezaei, Nima

“…[...]measures have not prevented the disease from spreading globally; COVID-19 has already spread to almost all countries and regions, and the World Health…”
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Anti-inflammatory effects of kolaviron modulate the expressions of inflammatory marker genes, inhibit transcription factors ERK1/2, p-JNK, NF-κB, and activate Akt expressions in the 93RS2 Sertoli cell lines by Abarikwu, Sunny O.

“…The anti-inflammatory effects of kolaviron (Kol-v) have been demonstrated in several experimental models. The ability of Kol-v to modulate the expressions of…”
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Acute effects of atrazine on the immunoexpressions of sertoli and germ cells molecular markers, cytokines, chemokines, and sex hormones levels in mice testes and epididymides by Abarikwu, Sunny O., Coimbra, John L.P., Campolina-Silva, Gabriel, Rocha, Samuel Tadeu, Costa, Vivian Vasconcelos, Lacerda, Samyra M.S.N., Costa, Guilherme M.J.

“…Atrazine is currently one of the most commonly used agrochemicals in the United States and elsewhere. Here, we studied the immunoexpression of molecular…”
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The protective effect of rutin against busulfan-induced testicular damage in adult rats by Abarikwu, Sunny O., Mgbudom-Okah, Chidimma J., Onuah, Chigozie L.

“…Here, we studied the protective effect of rutin (RUT) against testicular damage caused by busulfan (BUS) in rats. Adult male Wistar rats were intraperitoneally…”
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Protective effect of quercetin on atrazine-induced oxidative stress in the liver, kidney, brain, and heart of adult wistar rats by Abarikwu, Sunny O

“…The conflicting roles of quercetin against tissue pathologies associated with oxidative stress are known. To evaluate the effect of quercetin at doses of 5…”
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Characterization of leachates from waste landfill sites in a religious camp along Lagos-Ibadan expressway, Nigeria and its hepatotoxicity in rats by Ogunlaja, Aemere, Abarikwu, Sunny O., Otuechere, Chiagoziem A., Oshoro, Olufisayo O.

“…Landfill sites near human settlements are known to have adverse health effects. Here, we investigated the effect of different concentrations of leachates from…”
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Ascorbic acid attenuates gasoline-induced testicular toxicity, sperm quality deterioration, and testosterone imbalance in rats by Ezim, Ogechukwu E, Nyeche, Joy, Nebeolisa, Chisom E, Belonwu, Chuka D, Abarikwu, Sunny O

“…The present study evaluated the protective effect of ascorbic acid (ASCB) against gasoline fumes (PET) induced testicular oxidative stress, sperm toxicity, and…”
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Atrazine induces apoptosis of SH-SY5Y human neuroblastoma cells via the regulation of Bax/Bcl-2 ratio and caspase-3-dependent pathway by Abarikwu, Sunny O., Farombi, Ebenezer O.

“…[Display omitted] •Atrazine is a common environmental contaminant.•We study the cytotoxicity of atrazine in the human neuroblastoma SH-SY5Y cells.•Atrazine…”
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Biomarkers of oxidative stress and health risk assessment of heavy metal contaminated aquatic and terrestrial organisms by oil extraction industry in Ogale, Nigeria by Abarikwu, Sunny O., Essien, Eka B., Iyede, Oreva-Oghene, John, Kingsley, Mgbudom-Okah, Chidimma

“…Ogale community in Rivers State, Nigeria is characterized by crude-oil contamination of its land resources. The present study aimed to evaluate the health risk…”
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