Search Results - "Abaeva, Irina S"

Extraction of mRNA from Stalled Ribosomes by the Ski Complex by Zinoviev, Alexandra, Ayupov, Rustam K., Abaeva, Irina S., Hellen, Christopher U.T., Pestova, Tatyana V.

“…The evolutionarily conserved Ski2-Ski3-Ski8 (Ski) complex containing the 3′→5′ RNA helicase Ski2 binds to 80S ribosomes near the mRNA entrance and facilitates…”
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Nuclear Oncoprotein Prothymosin α Is a Partner of Keap1: Implications for Expression of Oxidative Stress-Protecting Genes by Karapetian, Ruben N., Evstafieva, Alexandra G., Abaeva, Irina S., Chichkova, Nina V., Filonov, Grigoriy S., Rubtsov, Yuri P., Sukhacheva, Elena A., Melnikov, Sergey V., Schneider, Ulrich, Wanker, Erich E., Vartapetian, Andrey B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The mechanism of translation initiation on Type 1 picornavirus IRESs by Sweeney, Trevor R, Abaeva, Irina S, Pestova, Tatyana V, Hellen, Christopher U T

“…Picornavirus Type 1 IRESs comprise five principal domains (dII–dVI). Whereas dV binds eIF4G, a conserved AUG in dVI was suggested to stimulate attachment of…”
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Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES by Brown, Zuben P, Abaeva, Irina S, De, Swastik, Hellen, Christopher U T, Pestova, Tatyana V, Frank, Joachim

“…Hepatitis C virus mRNA contains an internal ribosome entry site (IRES) that mediates end‐independent translation initiation, requiring a subset of eukaryotic…”
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In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g by Abaeva, Irina S, Arhab, Yani, Miścicka, Anna, Hellen, Christopher U T, Pestova, Tatyana V

“…SARS CoV-2 nonstructural protein 1 (Nsp1) is the major pathogenesis factor that inhibits host translation using a dual strategy of impairing initiation and…”
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Initiation of translation on nedicistrovirus and related intergenic region IRESs by their factor-independent binding to the P site of 80S ribosomes by Miścicka, Anna, Lu, Kristen, Abaeva, Irina S, Pestova, Tatyana V, Hellen, Christopher U T

“…Initiation of translation on many viral mRNAs occurs by noncanonical mechanisms that involve 5' end-independent binding of ribosomes to an internal ribosome…”
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The structure and mechanism of action of a distinct class of dicistrovirus intergenic region IRESs by Abaeva, Irina S, Young, Christina, Warsaba, Reid, Khan, Nadiyah, Tran, Lan Vy, Jan, Eric, Pestova, Tatyana V, Hellen, Christopher U T

“…Abstract Internal ribosomal entry sites (IRESs) engage with the eukaryotic translation apparatus to promote end-independent initiation. We identified a…”
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Attachment of ribosomal complexes and retrograde scanning during initiation on the Halastavi árva virus IRES by Abaeva, Irina S, Pestova, Tatyana V, Hellen, Christopher U T

“…Halastavi árva virus (HalV) has a positive-sense RNA genome, with an 827 nt-long 5' UTR and an intergenic region separating two open reading frames. Whereas…”
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eIF2-dependent and eIF2-independent modes of initiation on the CSFV IRES: a common role of domain II by Pestova, Tatyana V, de Breyne, Sylvain, Pisarev, Andrey V, Abaeva, Irina S, Hellen, Christopher U T

“…Specific interactions of the classical swine fever virus internal ribosomal entry site (IRES) with 40S ribosomal subunits and eukaryotic translation initiation…”
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The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism by Abaeva, Irina S., Vicens, Quentin, Bochler, Anthony, Soufari, Heddy, Simonetti, Angelita, Pestova, Tatyana V., Hashem, Yaser, Hellen, Christopher U.T.

“…Dicistrovirus intergenic region internal ribosomal entry sites (IGR IRESs) do not require initiator tRNA, an AUG codon, or initiation factors and jumpstart…”
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Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors by Yu, Yingpu, Abaeva, Irina S., Marintchev, Assen, Pestova, Tatyana V., Hellen, Christopher U. T.

“…Type 2 internal ribosomal entry sites (IRESs) of encephalomyocarditis virus (EMCV), foot-and-mouth disease virus (FMDV) and other picornaviruses comprise five…”
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Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning by Abaeva, Irina S, Marintchev, Assen, Pisareva, Vera P, Hellen, Christopher U T, Pestova, Tatyana V

“…Initiation codon selection in eukaryotes involves base‐by‐base inspection of the 5′‐untranslated region of mRNA by scanning ribosomal 43S preinitiation…”
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Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning: Ribosomal scanning on structured eukaryotic mRNAs by Abaeva, Irina S, Marintchev, Assen, Pisareva, Vera P, Hellen, Christopher U T, Pestova, Tatyana V

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