Search Results - "Abad, Maria M"

Identification of a characteristic copy number alteration profile by high‐resolution single nucleotide polymorphism arrays associated with metastatic sporadic colorectal cancer by González‐González, María, Fontanillo, Celia, Abad, María M., Gutiérrez, María L., Mota, Ines, Bengoechea, Oscar, Santos‐Briz, Ángel, Blanco, Oscar, Fonseca, Emilio, Ciudad, Juana, Fuentes, Manuel, Rivas, Javier, Alcazar, José A., García, Jacinto, Muñoz‐Bellvis, Luís, Orfao, Alberto, Sayagués, José M.

“…BACKGROUND Metastatic dissemination is the most frequent cause of death in patients with sporadic colorectal cancer (sCRC). It is believed that the metastatic…”
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Association Between the Cytogenetic Profile of Tumor Cells and Response to Preoperative Radiochemotherapy in Locally Advanced Rectal Cancer by González-González, María, Garcia, Jacinto, Alcazar, José A., Gutiérrez, María L., Gónzalez, Luis M., Bengoechea, Oscar, Abad, María M., Santos-Briz, Angel, Blanco, Oscar, Martín, Manuela, Rodríguez, Ana, Fuentes, Manuel, Muñoz-Bellvis, Luis, Orfao, Alberto, Sayagues, Jose M.

“…Neoadjuvant radiochemotherapy to locally advanced rectal carcinoma patients has proven efficient in a high percentage of cases. Despite this, some patients…”
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Uranium removal from complex mining waters by alginate beads doped with cells of Stenotrophomonas sp. Br8: Novel perspectives for metal bioremediation by Sánchez-Castro, Iván, Martínez-Rodríguez, Pablo, Abad, María M., Descostes, Michael, Merroun, Mohamed Larbi

“…Uranium-containing effluents generated by nuclear energy industry must be efficiently remediated before release to the environment. Currently, numerous…”
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Effect of different phosphate sources on uranium biomineralization by the Microbacterium sp. Be9 strain: A multidisciplinary approach study by Martínez-Rodríguez, Pablo, Sánchez-Castro, Iván, Ojeda, Jesús J, Abad, María M, Descostes, Michael, Merroun, Mohamed Larbi

“…Industrial activities related with the uranium industry are known to generate hazardous waste which must be managed adequately. Amongst the remediation…”
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Histologic Tumor Grade and Preoperative Bilary Drainage are the Unique Independent Prognostic Factors of Survival in Pancreatic Ductal Adenocarcinoma Patients After Pancreaticoduodenectomy by Macías, Nicolás, Sayagués, José M, Esteban, Carmen, Iglesias, Manuel, González, Luís M, Quiñones-Sampedro, Jose, Gutiérrez, María L, Corchete, Luís A, Abad, Maria M, Bengoechea, Oscar, Muñoz-Bellvis, Luís

“…BACKGROUND AND AIM:Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer; most patients die during the first 6 months after…”
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IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D) by Alcina, Antonio, Fedetz, María, Ndagire, Dorothy, Fernández, Oscar, Leyva, Laura, Guerrero, Miguel, Abad-Grau, María M, Arnal, Carmen, Delgado, Concepción, Lucas, Miguel, Izquierdo, Guillermo, Matesanz, Fuencisla

“…IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. Here…”
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Genome-wide association filtering using a highly locus-specific transmission/disequilibrium test by Abad-Grau, María M, Medina-Medina, Nuria, Montes-Soldado, Rosana, Moreno-Ortega, José, Matesanz, Fuencisla

“…Multimarker transmission/disequilibrium tests (TDTs) are powerful association and linkage tests used to perform genome-wide filtering in the search for disease…”
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A network model to predict the risk of death in sickle cell disease by Sebastiani, Paola, Nolan, Vikki G., Baldwin, Clinton T., Abad-Grau, Maria M., Wang, Ling, Adewoye, Adeboye H., McMahon, Lillian C., Farrer, Lindsay A., Taylor, James G., Kato, Gregory J., Gladwin, Mark T., Steinberg, Martin H.

“…Modeling the complexity of sickle cell disease pathophysiology and severity is difficult. Using data from 3380 patients accounting for all common genotypes of…”
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Operations strategy and flexibility: modeling with Bayesian classifiers by AbadGrau, Mara M., AriasAranda, Daniel

“…Purpose - Information analysis tools enhance the possibilities of firm competition in terms of knowledge management. However, the generalization of decision…”
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Building chromosome-wide LD maps by Abad-Grau, María M., Montes, Rosana, Sebastiani, Paola

“…BMapBuilder builds maps of pairwise linkage disequilibrium (LD) in either two or three dimensions. The optimized resolution allows for graphical display of LD…”
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Robust Transmission/Disequilibrium Test for Incomplete Family Genotypes by Sebastiani, Paola, Abad, Maria M, Alpargu, Gulhan, Ramoni, Marco F

“…Several solutions have been proposed to extend the transmission disequilibrium test (TDT) to include cases with missing parental genotype. However, completion…”
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A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples by Sebastiani, Paola, Zhao, Zhenming, Abad-Grau, Maria M, Riva, Alberto, Hartley, Stephen W, Sedgewick, Amanda E, Doria, Alessandro, Montano, Monty, Melista, Efthymia, Terry, Dellara, Perls, Thomas T, Steinberg, Martin H, Baldwin, Clinton T

“…One of the challenges of the analysis of pooling-based genome wide association studies is to identify authentic associations among potentially thousands of…”
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GeneOnEarth: Fitting Genetic PC Plots on the Globe by Torres-Sanchez, Sergio, Medina-Medina, Nuria, Gignoux, Chris, Abad-Grau, Maria M., Gonzalez-Burchard, Esteban

“…Principal component (PC) plots have become widely used to summarize genetic variation of individuals in a sample. The similarity between genetic distance in PC…”
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Evolution and challenges in the design of computational systems for triage assistance by Abad-Grau, María M., Ierache, Jorge, Cervino, Claudio, Sebastiani, Paola

“…Compared with expert systems for specific disease diagnosis, knowledge-based systems to assist decision making in triage usually try to cover a much wider…”
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Increasing power by using haplotype similarity in a multimarker transmission/disequilibrium test by Abad-Grau, María M, Medina-Medina, Nuria, Moral, Serafín, Montes-Soldado, Rosana, Torres-Sánchez, Sergio, Matesanz, Fuencisla

“…It is already known that power in multimarker transmission/disequilibrium tests may improve with the number of markers as some associations may require several…”
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Bayesian estimates of linkage disequilibrium by Sebastiani, Paola, Abad-Grau, María M

“…The maximum likelihood estimator of D'--a standard measure of linkage disequilibrium--is biased toward disequilibrium, and the bias is particularly evident in…”
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RNA Silencing in Aspergillus nidulans Is Independent of RNA-Dependent RNA Polymerases by Hammond, T. M, Keller, N. P

“…The versatility of RNA-dependent RNA polymerases (RDRPs) in eukaryotic gene silencing is perhaps best illustrated in the kingdom Fungi. Biochemical and genetic…”
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Fetal Hemoglobin (HbF) in Sickle Cell Anemia: Genome-Wide Association Studies Using Pooled DNA Samples Can Reveal Genetic Associations with HbF Concentration by Sebastiani, Paola, Abad-Grau, Maria M., Riva, Alberto A., Nolan, Vikki G., Melista, Efthimia, Steinberg, Martin H., Baldwin, Clinton T.

“…The complex regulatory environment controlling HbF levels provides ample opportunity for modulating expression of this key modifier of sickle cell anemia…”
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Severity of Sickle Cell Disease: Modeling Interrelationships among Hemolysis, Pulmonary Hypertension and Risk of Death by Sebastiani, Paola, Nolan, Vikki G., Baldwin, Clinton T., Abad-Grau, Maria M., Wang, Ling, Adewoye, Adeboye H., McMahon, Lillian C., Farrer, Lindsay A., Taylor, James G., Kato, Gregory J., Gladwin, Mark T., Steinberg, Martin H.

“…A single point mutation in the β hemoglobin gene causes sickle cell disease (SCD), but patients have extremely variable phenotypes. Hemolysis-related…”
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Immunohistochemical expression of p53 in breast carcinoma is associated with the intron 1 BglII polymorphism of the p53 gene by Trejo-Becerril, C, Sarmiento, R G, Abad, M M, Ichaso, N, Delgado, R, Cruz, J J, Dueñas-González, A

“…Breast carcinoma is a public health problem worldwide. It is known that both genetic and environmental factors are important for breast carcinogenesis and that…”
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