Search Results - "Abad, Jose L."

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization by Hernández-Tiedra, Sonia, Fabriàs, Gemma, Dávila, David, Salanueva, Íñigo J., Casas, Josefina, Montes, L. Ruth, Antón, Zuriñe, García-Taboada, Elena, Salazar-Roa, María, Lorente, Mar, Nylandsted, Jesper, Armstrong, Jane, López-Valero, Israel, McKee, Christopher S., Serrano-Puebla, Ana, García-López, Roberto, González-Martínez, José, Abad, José L., Hanada, Kentaro, Boya, Patricia, Goñi, Félix, Guzmán, Manuel, Lovat, Penny, Jäättelä, Marja, Alonso, Alicia, Velasco, Guillermo

“…Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2…”
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Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells by Kao, Li-Pin, Morad, Samy A.F., Davis, Traci S., MacDougall, Matthew R., Kassai, Miki, Abdelmageed, Noha, Fox, Todd E., Kester, Mark, Loughran, Thomas P., Abad, Jose' L., Fabrias, Gemma, Tan, Su-Fern, Feith, David J., Claxton, David F., Spiegel, Sarah, Fisher-Wellman, Kelsey H., Cabot, Myles C.

“…The combination of daunorubicin (dnr) and cytarabine (Ara-C) is a cornerstone of treatment for acute myelogenous leukemia (AML); resistance to these drugs is a…”
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Effects of Velocity-Based Resistance Training on Young Soccer Players of Different Ages by González-Badillo, Juan J, Pareja-Blanco, Fernando, Rodríguez-Rosell, David, Abad-Herencia, José L, del Ojo-López, Juan J, Sánchez-Medina, Luis

“…ABSTRACTGonzález-Badillo, JJ, Pareja-Blanco, F, Rodríguez-Rosell, D, Abad-Herencia, JL, del Ojo-López, JJ, and Sánchez-Medina, L. Effects of velocity-based…”
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Clearly Detectable, Kinetically Restricted Solid–Solid Phase Transition in cis-Ceramide Monolayers by Fanani, M. Laura, Busto, Jon V, Sot, Jesús, Abad, José L, Fabrías, Gemma, Saiz, Leonor, Vilar, Jose M. G, Goñi, Félix M, Maggio, Bruno, Alonso, Alicia

“…Sphingosine [(2S,3R,4E)-2-amino-4-octadecene-1,3-diol] is the most common sphingoid base in mammals. Ceramides are N-acyl sphingosines. Numerous small…”
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The T-box brain 1 (Tbr1) transcription factor inhibits astrocyte formation in the olfactory bulb and regulates neural stem cell fate by Méndez-Gómez, Héctor R., Vergaño-Vera, Eva, Abad, José L., Bulfone, Alessandro, Moratalla, Rosario, de Pablo, Flora, Vicario-Abejón, Carlos

“…The T-box brain 1 (Tbr1) gene encodes a transcription factor necessary for the maintenance and/or differentiation of glutamatergic cells in the olfactory bulb…”
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The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells by Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Solé, Sònia, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Muñoz-Pinedo, Cristina, Yoldi, Guillermo, Abad, Jose L, Segura, Miguel F, Moran, Teresa, Romeo, Margarita, Bosch-Barrera, Joaquim, Oaknin, Ana, Alfón, Jose, Domènech, Carles, Fabriàs, Gemma, Velasco, Guillermo, Lizcano, Jose M

“…ABTL0812 is a first-in-class small molecule with anti-cancer activity, which is currently in clinical evaluation in a phase 2 trial in patients with advanced…”
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Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy by Gagliostro, Vincenzo, Casas, Josefina, Caretti, Anna, Abad, Jose L., Tagliavacca, Luigina, Ghidoni, Riccardo, Fabrias, Gemma, Signorelli, Paola

“…Dihydroceramides, the precursors of ceramides in the de novo sphingolipid synthesis, have been recently implicated in active signalling. We previously…”
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Chirality-Puckering correlation and intermolecular interactions in Sphingosines: Rotational spectroscopy of jaspine B3 and its monohydrate by Saragi, Rizalina T., Juanes, Marcos, Abad, José L., Pinacho, Ruth, Rubio, José E., Lesarri, Alberto

“…[Display omitted] •Intra-/intermolecular interactions at the head group of Jaspine B analyzed rotationally.•Observation of six isomers of jaspine B and the…”
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Delayed administration of allogeneic cardiac stem cell therapy for acute myocardial infarction could ameliorate adverse remodeling: experimental study in swine by Crisostomo, Veronica, Baez-Diaz, Claudia, Maestre, Juan, Garcia-Lindo, Monica, Sun, Fei, Casado, Javier G, Blazquez, Rebeca, Abad, Jose L, Palacios, Itziar, Rodriguez-Borlado, Luis, Sanchez-Margallo, Francisco M

“…The optimal timing of cardiac stem cells administration is still unclear. We assessed the safety of same-day and delayed (one week) delivery and the possible…”
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Cellular Changes that Accompany Shedding of Human Corneocytes by Lin, Tzu-Kai, Crumrine, Debra, Ackerman, Larry D., Santiago, Juan-Luis, Roelandt, Truus, Uchida, Yoshikazu, Hupe, Melanie, Fabriàs, Gemma, Abad, Jose L., Rice, Robert H., Elias, Peter M.

“…Corneocyte desquamation has been ascribed to the following: 1) proteolytic degradation of corneodesmosomes (CDs); 2) disorganization of extracellular lamellar…”
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Microbial keratitis after corneal collagen crosslinking by Pérez-Santonja, Juan J., MD, Artola, Alberto, MD, Javaloy, Jaime, MD, Alió, Jorge L., MD, PhD, Abad, José L., PhD

“…Several infiltrates appeared in the upper midperipheral cornea of a 29-year-old woman who had had uneventful corneal collagen crosslinking (CXL) with…”
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Detection and Identification of Fungal Pathogens by PCR and by ITS2 and 5.8S Ribosomal DNA Typing in Ocular Infections by FERRER, Consuelo, COLOM, Francisca, FRASES, Susana, MULET, Emilia, ABAD, José L, ALIO, Jorge L

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Modulation of the PI 3-kinase-Akt signalling pathway by IGF-I and PTEN regulates the differentiation of neural stem/precursor cells by Otaegi, Gaizka, Yusta-Boyo, María J, Vergaño-Vera, Eva, Méndez-Gómez, Héctor R, Carrera, Ana C, Abad, José L, González, Manuel, de la Rosa, Enrique J, Vicario-Abejón, Carlos, de Pablo, Flora

“…Neural stem cells depend on insulin-like growth factor I (IGF-I) for differentiation. We analysed how activation and inhibition of the PI 3-kinase-Akt…”
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Pseudomonas keratitis 4 years after laser in situ keratomileusis by Ferrer, Consuelo, Rodriguez-Prats, Jose L, Abad, José L, Claramonte, Pascual, Alió, Jorge L, Signes-Soler, Isabel

“…To report a patient who presented an infectious keratitis 4 years after laser in situ keratomileusis (LASIK) without any other predisposing risk factor than…”
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Rapid Molecular Diagnosis of Posttraumatic Keratitis and Endophthalmitis Caused by Alternaria infectoria by FERRER, Consuelo, MONTERO, Javier, ALIO, Jorge L, ABAD, José L, RUIZ-MORENO, José M, COLOM, Francisca

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Polymerase chain reaction diagnosis in fungal keratitis caused by Alternaria alternata by Ferrer, Consuelo, Muñoz, Gonzalo, Alió, Jorge L, Abad, José L, Colomm, Francisca

“…PURPOSE: To contribute toward assessing the effectiveness of polymerase chain reaction as a rapid method in diagnosis of torpid keratitis caused by…”
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Unusual anaerobic bacteria in keratitis after laser in situ keratomileusis: diagnosis using molecular biology methods by Ferrer, Consuelo, Rodríguez-Prats, Jose L, Abad, José L, Alió, Jorge L

“…Laser in situ keratomileusis (LASIK) was performed in the left eye of a 57-year-old man for residual ametropia after phacoemulsification. The patient was given…”
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Nocardial keratitis after laser in situ keratomileusis by Pérez-Santonja, J J, Sakla, H F, Abad, J L, Zorraquino, A, Esteban, J, Alió, J L

“…Corneal interface central nodules appeared in a patient who underwent uncomplicated laser in situ keratomileusis (LASIK) retreatment for residual myopia…”
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A Hammerhead Ribozyme Targeted to the Human Chemokine Receptor CCR5 by González, Manuel A., Serrano, Fernando, Llorente, Mercedes, Abad, José L., Garcı́a-Ortiz, Marı́a J., Bernad, Antonio

“…The CCR5 chemokine receptor plays a crucial role in the initiation ofin vivoHIV infection, acting as a critical coreceptor molecule for primary strains…”
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