Search Results - "Aaron Sasson"

Mucins in pancreatic cancer and its microenvironment by Kaur, Sukhwinder, Kumar, Sushil, Momi, Navneet, Sasson, Aaron R., Batra, Surinder K.

“…Pancreatic cancer remains a lethal malignancy with poor prognosis. Here, the authors summarize emerging data on the role of mucins in the development and…”
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De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer by Tadros, Saber, Shukla, Surendra K, King, Ryan J, Gunda, Venugopal, Vernucci, Enza, Abrego, Jaime, Chaika, Nina V, Yu, Fang, Lazenby, Audrey J, Berim, Lyudmyla, Grem, Jean, Sasson, Aaron R, Singh, Pankaj K

“…Pancreatic adenocarcinoma is moderately responsive to gemcitabine-based chemotherapy, the most widely used single-agent therapy for pancreatic cancer. Although…”
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A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study by Kaur, Sukhwinder, Smith, Lynette M, Patel, Asish, Menning, Melanie, Watley, Duncan C, Malik, Saad S, Krishn, Shiv Ram, Mallya, Kavita, Aithal, Abhijit, Sasson, Aaron R, Johansson, Sonny L, Jain, Maneesh, Singh, Shailender, Guha, Sushovan, Are, Chandrakanth, Raimondo, Massimo, Hollingsworth, Michael A, Brand, Randall E, Batra, Surinder K

“…Pancreatic cancer (PC) is a lethal malignancy that lacks specific diagnostic markers. The present study explores the diagnostic potential of the most…”
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Transcriptional profiling of peripheral blood mononuclear cells in pancreatic cancer patients identifies novel genes with potential diagnostic utility by Baine, Michael J, Chakraborty, Subhankar, Smith, Lynette M, Mallya, Kavita, Sasson, Aaron R, Brand, Randall E, Batra, Surinder K

“…It is well known that many malignancies, including pancreatic cancer (PC), possess the ability to evade the immune system by indirectly downregulating the…”
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Development of Patient-Derived Gastric Cancer Organoids from Endoscopic Biopsies and Surgical Tissues by Gao, Mei, Lin, Miranda, Rao, Manisha, Thompson, Hannah, Hirai, Kelsi, Choi, Minsig, Georgakis, Georgios V., Sasson, Aaron R., Bucobo, Juan Carlos, Tzimas, Demetri, D’Souza, Lionel S., Buscaglia, Jonathan M., Davis, James, Shroyer, Kenneth R., Li, Jinyu, Powers, Scott, Kim, Joseph

“…Background Organoids are three-dimensional in vitro models of human disease developed from benign and malignant gastrointestinal tissues with tremendous…”
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Successful creation of pancreatic cancer organoids by means of EUS-guided fine-needle biopsy sampling for personalized cancer treatment by Tiriac, Herve, Bucobo, Juan Carlos, Tzimas, Demetrios, Grewel, Suman, Lacomb, Joseph F., Rowehl, Leahana M., Nagula, Satish, Wu, Maoxin, Kim, Joseph, Sasson, Aaron, Vignesh, Shivakumar, Martello, Laura, Munoz-Sagastibelza, Maria, Somma, Jonathan, Tuveson, David A., Li, Ellen, Buscaglia, Jonathan M.

“…Pancreatic cancer organoids are tumor models of individualized human pancreatic ductal adenocarcinoma (PDA), created from surgical specimens and used for…”
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Early diagnosis of pancreatic cancer: challenges and new developments by Kaur, Sukhwinder, Baine, Michael J, Jain, Maneesh, Sasson, Aaron R, Batra, Surinder K

“…Pancreatic cancer is a lethal malignancy with its incidence almost equivalent to mortality. The complex pathophysiology, absence of early diagnostic and…”
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The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Management of Metastatic and/or Unresectable Pheochromocytoma and Paraganglioma by Fishbein, Lauren, Del Rivero, Jaydira, Else, Tobias, Howe, James R., Asa, Sylvia L., Cohen, Debbie L., Dahia, Patricia L.M., Fraker, Douglas L., Goodman, Karyn A., Hope, Thomas A., Kunz, Pamela L., Perez, Kimberly, Perrier, Nancy D., Pryma, Daniel A., Ryder, Mabel, Sasson, Aaron R., Soulen, Michael C., Jimenez, Camilo

“…This manuscript is the result of the North American Neuroendocrine Tumor Society consensus conference on the medical management and surveillance of metastatic…”
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Coordinated single-cell tumor microenvironment dynamics reinforce pancreatic cancer subtype by Oh, Ki, Yoo, Yun Jae, Torre-Healy, Luke A., Rao, Manisha, Fassler, Danielle, Wang, Pei, Caponegro, Michael, Gao, Mei, Kim, Joseph, Sasson, Aaron, Georgakis, Georgios, Powers, Scott, Moffitt, Richard A.

“…Bulk analyses of pancreatic ductal adenocarcinoma (PDAC) samples are complicated by the tumor microenvironment (TME), i.e. signals from fibroblasts, endocrine,…”
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Development of cancer after bariatric surgery by Tsui, Stella T., Yang, Jie, Zhang, Xiaoyue, Docimo, Salvatore, Spaniolas, Konstantinos, Talamini, Mark A., Sasson, Aaron R., Pryor, Aurora D.

“…Although bariatric surgery has been associated with a reduction in risk of obesity-related cancer, data on the effect of bariatric interventions on other…”
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Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines by Ajani, Jaffer A, Bentrem, David J, Besh, Stephen, D'Amico, Thomas A, Das, Prajnan, Denlinger, Crystal, Fakih, Marwan G, Fuchs, Charles S, Gerdes, Hans, Glasgow, Robert E, Hayman, James A, Hofstetter, Wayne L, Ilson, David H, Keswani, Rajesh N, Kleinberg, Lawrence R, Korn, W Michael, Lockhart, A Craig, Meredith, Kenneth, Mulcahy, Mary F, Orringer, Mark B, Posey, James A, Sasson, Aaron R, Scott, Walter J, Strong, Vivian E, Varghese, Jr, Thomas K, Warren, Graham, Washington, Mary Kay, Willett, Christopher, Wright, Cameron D, McMillian, Nicole R, Sundar, Hema

“…The NCCN Clinical Practice Guidelines in Oncology for Gastric Cancer provide evidence- and consensus-based recommendations for a multidisciplinary approach for…”
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Pancreatic adenocarcinoma, version 2.2014: featured updates to the NCCN guidelines by Tempero, Margaret A, Malafa, Mokenge P, Behrman, Stephen W, Benson, 3rd, Al B, Casper, Ephraim S, Chiorean, E Gabriela, Chung, Vincent, Cohen, Steven J, Czito, Brian, Engebretson, Anitra, Feng, Mary, Hawkins, William G, Herman, Joseph, Hoffman, John P, Ko, Andrew, Komanduri, Srinadh, Koong, Albert, Lowy, Andrew M, Ma, Wen Wee, Merchant, Nipun B, Mulvihill, Sean J, Muscarella, 2nd, Peter, Nakakura, Eric K, Obando, Jorge, Pitman, Martha B, Reddy, Sushanth, Sasson, Aaron R, Thayer, Sarah P, Weekes, Colin D, Wolff, Robert A, Wolpin, Brian M, Burns, Jennifer L, Freedman-Cass, Deborah A

“…The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and management of adenocarcinomas of the exocrine pancreas and are intended to assist…”
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Esophageal and esophagogastric junction cancers, version 1.2015 by Ajani, Jaffer A, D'Amico, Thomas A, Almhanna, Khaldoun, Bentrem, David J, Besh, Stephen, Chao, Joseph, Das, Prajnan, Denlinger, Crystal, Fanta, Paul, Fuchs, Charles S, Gerdes, Hans, Glasgow, Robert E, Hayman, James A, Hochwald, Steven, Hofstetter, Wayne L, Ilson, David H, Jaroszewski, Dawn, Jasperson, Kory, Keswani, Rajesh N, Kleinberg, Lawrence R, Korn, W Michael, Leong, Stephen, Lockhart, A Craig, Mulcahy, Mary F, Orringer, Mark B, Posey, James A, Poultsides, George A, Sasson, Aaron R, Scott, Walter J, Strong, Vivian E, Varghese, Jr, Thomas K, Washington, Mary Kay, Willett, Christopher G, Wright, Cameron D, Zelman, Debra, McMillian, Nicole, Sundar, Hema

“…Esophageal cancer is the sixth most common cause of cancer deaths worldwide. Adenocarcinoma is more common in North America and Western European countries,…”
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Current status of molecular markers for early detection of sporadic pancreatic cancer by Chakraborty, Subhankar, Baine, Michael J., Sasson, Aaron R., Batra, Surinder K.

“…Pancreatic cancer (PC) is a highly lethal malignancy with near 100% mortality. This is in part due to the fact that most patients present with metastatic or…”
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Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer by Gao, Mei, Lin, Miranda, Moffitt, Richard A., Salazar, Marcela A., Park, Jinha, Vacirca, Jeffrey, Huang, Chuan, Shroyer, Kenneth R., Choi, Minsig, Georgakis, Georgios V., Sasson, Aaron R., Talamini, Mark A., Kim, Joseph

“…Background Pancreatic cancer (PC) hijacks innate cellular processes to promote cancer growth. We hypothesized that PC exploits PD-1/PD-L1 not only to avoid…”
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Advanced pancreatic cancer: a meta-analysis of clinical trials over thirty years by Hall, Bradley R, Cannon, Andrew, Atri, Pranita, Wichman, Christopher S, Smith, Lynette M, Ganti, Apar K, Are, Chandrakanth, Sasson, Aaron R, Kumar, Sushil, Batra, Surinder K

“…In contrast to other cancers, survival rates for pancreatic ductal adenocarcinoma (PDAC) patients have improved but minimally over the past thirty years. The…”
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Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines by Tempero, Margaret A, Arnoletti, J Pablo, Behrman, Stephen W, Ben-Josef, Edgar, Benson, 3rd, Al B, Casper, Ephraim S, Cohen, Steven J, Czito, Brian, Ellenhorn, Joshua D I, Hawkins, William G, Herman, Joseph, Hoffman, John P, Ko, Andrew, Komanduri, Srinadh, Koong, Albert, Ma, Wen Wee, Malafa, Mokenge P, Merchant, Nipun B, Mulvihill, Sean J, Muscarella, 2nd, Peter, Nakakura, Eric K, Obando, Jorge, Pitman, Martha B, Sasson, Aaron R, Tally, Anitra, Thayer, Sarah P, Whiting, Samuel, Wolff, Robert A, Wolpin, Brian M, Freedman-Cass, Deborah A, Shead, Dorothy A

“…The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pancreatic Adenocarcinoma discuss the workup and management of tumors of the exocrine…”
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Tumor Biomarker In-Solution Quantification, Standard Production, and Multiplex Detection by Japp, Nicole C., Souchek, Joshua J., Sasson, Aaron R., Hollingsworth, Michael A., Batra, Surinder K., Junker, Wade M.

“…The diagnosis and monitoring of cancer have been facilitated by discovering tumor “biomarkers” and methods to detect their presence. Yet, for certain cancers,…”
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Phase I trial of concurrent stereotactic body radiotherapy and nelfinavir for locally advanced borderline or unresectable pancreatic adenocarcinoma by Lin, Chi, Verma, Vivek, Ly, Quan P., Lazenby, Audrey, Sasson, Aaron, Schwarz, James K., Meza, Jane L., Are, Chandrakanth, Li, Sicong, Wang, Shuo, Hahn, Stephen M., Grem, Jean L.

“…•No studies have assessed SBRT + NFV for borderline/unresectable pancreatic cancer.•This phase I trial enrolled 46 patients, of which 39 received per-protocol…”
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Dosimetric parameters correlate with duodenal histopathologic damage after stereotactic body radiotherapy for pancreatic cancer: Secondary analysis of a prospective clinical trial by Verma, Vivek, Lazenby, Audrey J, Zheng, Dandan, Bhirud, Abhijeet R, Ly, Quan P, Are, Chandrakanth, Sasson, Aaron R, Lin, Chi

“…Abstract Purpose Prospectively assess relationships between dosimetric parameters and histopathologic/clinical duodenal toxicities in patients on a phase I…”
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