Search Results - "Aarestrup, Frank"
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In Silico Detection and Typing of Plasmids using PlasmidFinder and Plasmid Multilocus Sequence Typing
Published in Antimicrobial agents and chemotherapy (01-07-2014)“…In the work presented here, we designed and developed two easy-to-use Web tools for in silico detection and characterization of whole-genome sequence (WGS) and…”
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2
The livestock reservoir for antimicrobial resistance: a personal view on changing patterns of risks, effects of interventions and the way forward
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-06-2015)“…The purpose of this review was to provide an updated overview on the use of antimicrobial agents in livestock, the associated problems for humans and current…”
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3
Solving the problem of comparing whole bacterial genomes across different sequencing platforms
Published in PloS one (11-08-2014)“…Whole genome sequencing (WGS) shows great potential for real-time monitoring and identification of infectious disease outbreaks. However, rapid and reliable…”
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4
Rapid and precise alignment of raw reads against redundant databases with KMA
Published in BMC bioinformatics (29-08-2018)“…As the cost of sequencing has declined, clinical diagnostics based on next generation sequencing (NGS) have become reality. Diagnostics based on sequencing…”
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5
A Bacterial Analysis Platform: An Integrated System for Analysing Bacterial Whole Genome Sequencing Data for Clinical Diagnostics and Surveillance
Published in PloS one (21-06-2016)“…Recent advances in whole genome sequencing have made the technology available for routine use in microbiological laboratories. However, a major obstacle for…”
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Comparative Evaluation of the Antimicrobial Activity of Different Antimicrobial Peptides against a Range of Pathogenic Bacteria
Published in PloS one (11-12-2015)“…The rapid emergence of resistance to classical antibiotics has increased the interest in novel antimicrobial compounds. Antimicrobial peptides (AMPs) represent…”
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7
Using sewage for surveillance of antimicrobial resistance
Published in Science (American Association for the Advancement of Science) (07-02-2020)“…A global system would exploit metagenomic sequencing Antimicrobial resistance (AMR), a cross-cutting and increasing threat to global health ( 1 – 3 ), is a…”
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PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens
Published in Journal of antimicrobial chemotherapy (01-10-2017)“…Antibiotic resistance is a major health problem, as drugs that were once highly effective no longer cure bacterial infections. WGS has previously been shown to…”
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Evaluation of whole genome sequencing for outbreak detection of Salmonella enterica
Published in PloS one (04-02-2014)“…Salmonella enterica is a common cause of minor and large food borne outbreaks. To achieve successful and nearly 'real-time' monitoring and identification of…”
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10
Detection of mobile genetic elements associated with antibiotic resistance in Salmonella enterica using a newly developed web tool: MobileElementFinder
Published in Journal of antimicrobial chemotherapy (01-01-2021)“…Antimicrobial resistance (AMR) in clinically relevant bacteria is a growing threat to public health globally. In these bacteria, antimicrobial resistance genes…”
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11
Identification of acquired antimicrobial resistance genes
Published in Journal of antimicrobial chemotherapy (01-11-2012)“…Identification of antimicrobial resistance genes is important for understanding the underlying mechanisms and the epidemiology of antimicrobial resistance. As…”
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ResFinder - an open online resource for identification of antimicrobial resistance genes in next-generation sequencing data and prediction of phenotypes from genotypes
Published in Microbial genomics (01-01-2022)“…Antimicrobial resistance (AMR) is one of the most important health threats globally. The ability to accurately identify resistant bacterial isolates and the…”
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13
A metagenomic glimpse into the gut of wild and domestic animals: Quantification of antimicrobial resistance and more
Published in PloS one (03-12-2020)“…Antimicrobial resistance (AMR) in bacteria is a complex subject, why one need to look at this phenomenon from a wider and holistic perspective. The extensive…”
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14
Evaluation of Methods for the Concentration and Extraction of Viruses from Sewage in the Context of Metagenomic Sequencing
Published in PloS one (18-01-2017)“…Viral sewage metagenomics is a novel field of study used for surveillance, epidemiological studies, and evaluation of waste water treatment efficiency. In raw…”
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MGmapper: Reference based mapping and taxonomy annotation of metagenomics sequence reads
Published in PloS one (03-05-2017)“…An increasing amount of species and gene identification studies rely on the use of next generation sequence analysis of either single isolate or metagenomics…”
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Real-time whole-genome sequencing for routine typing, surveillance, and outbreak detection of verotoxigenic Escherichia coli
Published in Journal of clinical microbiology (01-05-2014)“…Fast and accurate identification and typing of pathogens are essential for effective surveillance and outbreak detection. The current routine procedure is…”
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17
Characterization and Genetic Variation of Vibrio cholerae Isolated from Clinical and Environmental Sources in Thailand
Published in PloS one (19-01-2017)“…Cholera is still an important public health problem in several countries, including Thailand. In this study, a collection of clinical and environmental V…”
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18
Detection of specific uncultured bacteriophages by fluorescence in situ hybridisation in pig microbiome
Published in PloS one (30-03-2023)“…Microbial communities have huge impacts on their ecosystems and local environments spanning from marine and soil communities to the mammalian gut…”
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Rapid and Easy In Silico Serotyping of Escherichia coli Isolates by Use of Whole-Genome Sequencing Data
Published in Journal of clinical microbiology (01-08-2015)“…Accurate and rapid typing of pathogens is essential for effective surveillance and outbreak detection. Conventional serotyping of Escherichia coli is a…”
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The Role of Outer Membrane Proteins and Lipopolysaccharides for the Sensitivity of Escherichia coli to Antimicrobial Peptides
Published in Frontiers in microbiology (07-09-2018)“…Bacterial resistance to classical antibiotics is emerging worldwide. The number of infections caused by multidrug resistant bacteria is increasing and becoming…”
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