Search Results - "Aaltonen, L.‐M."

Supragastric belch may be related to globus symptom – a prospective clinical study by Nevalainen, P., Walamies, M., Kruuna, O., Arkkila, P., Aaltonen, L.‐M.

“…Background The etiology of globus is poorly understood. It is controversial, whether gastroesophageal reflux disease (GERD) has a role in globus. To…”
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Patient injuries in operative rhinology during a ten‐year period: Review of national patient insurance charts by Blomgren, K., Aaltonen, L.‐M., Lehtonen, L., Helmiö, P.

“…Objectives To assess factors contributing to patient injuries in operative rhinology. Design Data of the accepted patient injury claims involving operative…”
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A new quantitative PCR for human parvovirus B19 genotypes by Toppinen, M., Norja, P., Aaltonen, L.-M., Wessberg, S., Hedman, L., Söderlund-Venermo, M., Hedman, K.

“…•For clinical and scientific purposes a new parvovirus B19 (B19V) qPCR was developed.•The qPCR amplifies and quantifies all three B19V genotypes, with high…”
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Towards better patient safety in otolaryngology: characteristics of patient injuries and their relationship with items on the WHO Surgical Safety Checklist by Helmiö, P., Blomgren, K., Lehtivuori, T., Palonen, R., Aaltonen, L.-M.

“…Objectives Increasing knowledge of factors contributing to medical adverse events has influenced the development of preventive policies and protocols, the WHO…”
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Association of breathing sound spectra with glottal dimensions in exercise-induced vocal cord dysfunction by Geneid, Ahmed, Aaltonen, L.-M., Porra, L., Peltonen, J., Palmu, K., Sovijärvi, A., Piirilä, P.

“…The objective of this study was to evaluate associations between the breathing sound spectra and glottal dimensions in exercise-induced vocal cord dysfunction…”
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Limited long‐term outcome of single‐session soft palate interstitial radiofrequency surgery for habitual snoring in tertiary care academic referral centre: Our experience on 77 patients by Sinkkonen, S. T., Ruohoalho, J., Pietarinen, P., Aaltonen, L.‐M., Mäkitie, A. A., Bäck, L. J.

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The MDM2 promoter polymorphism SNP309T→G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck by Alhopuro, P, Ylisaukko-oja, S K, Koskinen, W J, Bono, P, Arola, J, Järvinen, H J, Mecklin, J-P, Atula, T, Kontio, R, Mäkitie, A A, Suominen, S, Leivo, I, Vahteristo, P, Aaltonen, L-M, Aaltonen, L A

“…Background: MDM2 acts as a principal regulator of the tumour suppressor p53 by targeting its destruction through the ubiquitin pathway. A polymorphism in the…”
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First year with WHO Surgical Safety Checklist in 7148 otorhinolaryngological operations: use and user attitudes by Helmiö, P., Takala, A., Aaltonen, L.-M., Pauniaho, S.-L., Ikonen, T.S., Blomgren, K.

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Citric acid as excipient in multiple-unit enteric-coated tablets for targeting drugs on the colon by Nykänen, P, Lempää, S, Aaltonen, M.-L, Jürjenson, H, Veski, P, Marvola, M

“…Delivery of drugs to the large bowel has been extensively investigated during the last decade. The aim of this study was to investigate whether enteric-coated…”
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HLA-DQ Alleles and Human Papillomavirus DNA in Adult-Onset Laryngeal Papillomatosis by Aaltonen, L.-M., Partanen, J., Auvinen, E., Rihkanen, H., Vaheri, A.

“…Sixty-two patients with histologically confirmed adult-onset laryngeal papilloma were clinically examined; their HLA class II DQA1 and DQB1 alleles and the…”
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Survival and Larynx Preservation in Early Glottic Cancer: A Randomized Trial Comparing Laser Surgery and Radiation Therapy by Pakkanen, Pihla, Irjala, Heikki, Ilmarinen, Taru, Halme, Elina, Lindholm, Paula, Mäkitie, Antti, Wigren, Tuija, Aaltonen, Leena-Maija

“…The prognosis of glottic T1a laryngeal squamous cell carcinoma (LSCC) is excellent with both transoral laser surgery (TLS) and radiation therapy (RT). Our aim…”
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HPV‐Positive Status Is an Independent Factor Associated With Sinonasal Inverted Papilloma Recurrence by Viitasalo, Sanna, Ilmarinen, Taru, Lilja, Markus, Hytönen, Maija, Hammarén‐Malmi, Sari, Auvinen, Eeva, Hagström, Jaana, Dillner, Joakim, Aaltonen, Leena‐Maija

“…Objectives The present study aimed to evaluate human papillomavirus (HPV) occurrence in sinonasal inverted papilloma (SNIP), and to assess factors associated…”
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Voice Quality After Treatment of Early Vocal Cord Cancer: A Randomized Trial Comparing Laser Surgery With Radiation Therapy by Aaltonen, Leena-Maija, MD, PhD, Rautiainen, Noora, MA, Sellman, Jaana, PhD, Saarilahti, Kauko, MD, PhD, Mäkitie, Antti, MD, Rihkanen, Heikki, MD, PhD, Laranne, Jussi, MD, PhD, Kleemola, Leenamaija, MD, PhD, Wigren, Tuija, MD, PhD, Sala, Eeva, MD, PhD, Lindholm, Paula, MD, PhD, Grenman, Reidar, MD, Joensuu, Heikki, MD

“…Objective Early laryngeal cancer is usually treated with either transoral laser surgery or radiation therapy. The quality of voice achieved with these…”
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Postoperative Infection Following Nasal Septoplasty by Mäkitie, A.

“…This retrospective study evaluates the incidence and spectrum of infectious complications in 100 consecutive adult nasal septoplasty patients. A total of 12…”
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Poor antibody response against human papillomavirus in adult-onset laryngeal papillomatosis by AALTONEN, L.-M, AUVINEN, E, DILLNER, J, LEHTINEN, M, PAAVONEN, J, RIHKANEN, H, VAHERI, A

“…*Department of Virology, Haartman Institute, University of Helsinki, Departments of Otorhinolaryngology and Gynecology and Obstetrics, Helsinki University…”
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Establishment and characterisation of human papillomavirus type 16 DNA immortalised human tonsillar epithelial cell lines by Chen, R.W, Aalto, Y, Teesalu, T, Dürst, M, Knuutila, S, Aaltonen, L.-M, Vaheri, A

“…Oncogenic human papillomavirus (HPV) plays a possible aetiological role in a subset of head and neck cancers, particularly in tonsillar carcinomas. For…”
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Laryngeal cancer in Finland: A 5-year follow-up study of 366 patients by Haapaniemi, Aaro, Koivunen, Petri, Saarilahti, Kauko, Kinnunen, Ilpo, Laranne, Jussi, Aaltonen, Leena-Maija, Närkiö, Mervi, Lindholm, Paula, Grénman, Reidar, Mäkitie, Antti, Atula, Timo

“…ABSTRACT Background The purpose of this study was to acquire nationwide data on the management and outcome of laryngeal squamous cell carcinoma (SCC) in…”
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A novel method to culture laryngeal human papillomavirus-positive epithelial cells produces papilloma-type cytology on collagen rafts by Aaltonen, L.-M, Wahlström, T, Rihkanen, H, Vaheri, A

“…A novel method to culture human papillomavirus (HPV) positive laryngeal epithelial cells is described. Biopsies of laryngeal papillomas and of HPV-positive…”
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Multiplex detection in tonsillar tissue of all known human polyomaviruses by Sadeghi, Mohammadreza, Wang, Yilin, Ramqvist, Torbjörn, Aaltonen, Leena-Maija, Pyöriä, Lari, Toppinen, Mari, Söderlund-Venermo, Maria, Hedman, Klaus

“…In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of…”
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Safety of intralesional cidofovir in patients with recurrent respiratory papillomatosis: an international retrospective study on 635 RRP patients by Tjon Pian Gi, R. E. A., Ilmarinen, T., van den Heuvel, E. R., Aaltonen, L. M., Andersen, J., Brunings, J. W., Chirila, M., Dietz, A., Ferran Vilà, F., Friedrich, G., de Gier, H. H. W., Golusinski, W., Graupp, M., Hantzakos, A., Horcasitas, R., Jackowska, J., Koelmel, J. C., Lawson, G., Lindner, F., Remacle, M., Sittel, C., Weichbold, V., Wierzbicka, M., Dikkers, F. G.

“…Intralesional use of cidofovir (Vistide ® ) has been one of the mainstays of adjuvant therapy in patients with recurrent respiratory papillomatosis (RRP) since…”
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