Search Results - "Aachmann, Finn L."

A C4-oxidizing Lytic Polysaccharide Monooxygenase Cleaving Both Cellulose and Cello-oligosaccharides by Isaksen, Trine, Westereng, Bjørge, Aachmann, Finn L., Agger, Jane W., Kracher, Daniel, Kittl, Roman, Ludwig, Roland, Haltrich, Dietmar, Eijsink, Vincent G.H., Horn, Svein J.

“…Lignocellulosic biomass is a renewable resource that significantly can substitute fossil resources for the production of fuels, chemicals, and materials…”
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NMR structure of a lytic polysaccharide monooxygenase provides insight into copper binding, protein dynamics, and substrate interactions by Aachmann, Finn L, Sørlie, Morten, Skjåk-Bræk, Gudmund, Eijsink, Vincent G. H, Vaaje-Kolstad, Gustav

“…Lytic polysaccharide monooxygenases currently classified as carbohydrate binding module family 33 (CBM33) and glycoside hydrolase family 61 (GH61) are likely…”
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Efficient functionalization of alginate biomaterials by Dalheim, Marianne Ø, Vanacker, Julie, Najmi, Maryam A, Aachmann, Finn L, Strand, Berit L, Christensen, Bjørn E

“…Abstract Peptide coupled alginates obtained by chemical functionalization of alginates are commonly used as scaffold materials for cells in regenerative…”
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The Structure and Regulation of Human Muscle α-Actinin by Ribeiro, Euripedes de Almeida, Pinotsis, Nikos, Ghisleni, Andrea, Salmazo, Anita, Konarev, Petr V., Kostan, Julius, Sjöblom, Björn, Schreiner, Claudia, Polyansky, Anton A., Gkougkoulia, Eirini A., Holt, Mark R., Aachmann, Finn L., Žagrović, Bojan, Bordignon, Enrica, Pirker, Katharina F., Svergun, Dmitri I., Gautel, Mathias, Djinović-Carugo, Kristina

“…The spectrin superfamily of proteins plays key roles in assembling the actin cytoskeleton in various cell types, crosslinks actin filaments, and acts as…”
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Simultaneous analysis of C1 and C4 oxidized oligosaccharides, the products of lytic polysaccharide monooxygenases acting on cellulose by Westereng, Bjørge, Arntzen, Magnus Ø., Aachmann, Finn L., Várnai, Anikó, Eijsink, Vincent G.H., Agger, Jane Wittrup

“…•PGC for quantitative and qualitative analysis of C1 and C4 oxidized cello-oligomers.•C4-oxidized LPMO products undergo on-column decomposition during HPAEC…”
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Efficient separation of oxidized cello-oligosaccharides generated by cellulose degrading lytic polysaccharide monooxygenases by Westereng, Bjørge, Agger, Jane Wittrup, Horn, Svein J., Vaaje-Kolstad, Gustav, Aachmann, Finn L., Stenstrøm, Yngve H., Eijsink, Vincent G.H.

“…► We show efficient separation of cello-oligosaccharides and their aldonic acids. ► Using HPAEC, run times can be as short as 10min. ► HILIC and PGC-LC methods…”
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Molecular insights into alginate β‐lactoglobulin A multivalencies—The foundation for their amorphous aggregates and coacervation by Madsen, Mikkel, Prestel, Andreas, Madland, Eva, Westh, Peter, Tøndervik, Anne, Sletta, Håvard, Peters, Günther H. J., Aachmann, Finn L., Kragelund, Birthe B., Svensson, Birte

“…For improved control of biomaterial property design, a better understanding of complex coacervation involving anionic polysaccharides and proteins is needed…”
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A glycan receptor kinase facilitates intracellular accommodation of arbuscular mycorrhiza and symbiotic rhizobia in the legume Lotus japonicus by Kelly, Simon, Hansen, Simon B, Rübsam, Henriette, Saake, Pia, Pedersen, Emil B, Gysel, Kira, Madland, Eva, Wu, Shunliang, Wawra, Stephan, Reid, Dugald, Sullivan, John T, Blahovska, Zuzana, Vinther, Maria, Muszynski, Artur, Azadi, Parastoo, Thygesen, Mikkel B, Aachmann, Finn L, Ronson, Clive W, Zuccaro, Alga, Andersen, Kasper R, Radutoiu, Simona, Stougaard, Jens

“…Receptors that distinguish the multitude of microbes surrounding plants in the environment enable dynamic responses to the biotic and abiotic conditions…”
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Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates by Østby, Heidi, Christensen, Idd A., Hennum, Karen, Várnai, Anikó, Buchinger, Edith, Grandal, Siri, Courtade, Gaston, Hegnar, Olav A., Aachmann, Finn L., Eijsink, Vincent G. H.

“…Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that use O 2 or H 2 O 2 to oxidatively cleave glycosidic bonds. LPMOs are prevalent in…”
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Preparation of 4‑Deoxy‑L-erythro-5-hexoseulose Uronic Acid (DEH) and Guluronic Acid Rich Alginate Using a Unique exo-Alginate Lyase from Thalassotalea crassostreae by Wang, Damao, Aarstad, Olav A, Li, Jing, McKee, Lauren S, Sætrom, Gerd Inger, Vyas, Anisha, Srivastava, Vaibhav, Aachmann, Finn L, Bulone, Vincent, Hsieh, Yves SY

“…Marine multicellular algae are considered promising crops for the production of sustainable biofuels and commodity chemicals. However, their commercial…”
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The Impact of Chain Length and Flexibility in the Interaction between Sulfated Alginates and HGF and FGF‑2 by Arlov, Øystein, Aachmann, Finn L, Feyzi, Emadoldin, Sundan, Anders, Skjåk-Bræk, Gudmund

“…Alginate is a promising polysaccharide for use in biomaterials as it is biologically inert. One way to functionalize alginate is by chemical sulfation to…”
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Bi-Functional Alginate Oligosaccharide-Polymyxin Conjugates for Improved Treatment of Multidrug-Resistant Gram-Negative Bacterial Infections by Stokniene, Joana, Powell, Lydia C, Aarstad, Olav A, Aachmann, Finn L, Rye, Philip D, Hill, Katja E, Thomas, David W, Ferguson, Elaine L

“…The recent emergence of resistance to colistin, an antibiotic of last resort with dose-limiting toxicity, has highlighted the need for alternative approaches…”
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Unaided efficient transglutaminase cross-linking of whey proteins strongly impacts the formation and structure of protein alginate particles by Madsen, Mikkel, Khan, Sanaullah, Kunstmann, Sonja, Aachmann, Finn L., Ipsen, Richard, Westh, Peter, Emanuelsson, Cecilia, Svensson, Birte

“…• Microbial transglutaminase (MTG) cross-linked >70% β-lactoglobulin (β-Lg) at pH 8.5. • Initial MTG catalyzed isopeptide bond formation caused partial…”
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Solution Structure of Selenoprotein W and NMR Analysis of Its Interaction with 14-3-3 Proteins by Aachmann, Finn L., Fomenko, Dmitri E., Soragni, Alice, Gladyshev, Vadim N., Dikiy, Alexander

“…Selenium is a trace element with significant biomedical potential. It is essential in mammals due to its occurrence in several proteins in the form of…”
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Identification of a Pivotal Residue for Determining the Block Structure-Forming Properties of Alginate C‑5 Epimerases by Stanisci, Annalucia, Tøndervik, Anne, Gaardløs, Margrethe, Lervik, Anders, Skjåk-Bræk, Gudmund, Sletta, Håvard, Aachmann, Finn L

“…Alginate is a linear copolymer composed of 1→4 linked β-d-mannuronic acid (M) and its epimer α-l-guluronic acid (G). The polysaccharide is first produced as…”
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Mechanical Properties of Ca-Saturated Hydrogels with Functionalized Alginate by Dalheim, Marianne Ø, Omtvedt, Line Aa, Bjørge, Isabel M, Akbarzadeh, Anita, Mano, João F, Aachmann, Finn L, Strand, Berit L

“…In this work, the mechanical properties and stability of alginate hydrogels containing functionalized alginates (peptide and β-cyclodextrin) were studied…”
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Generic tools to assess genuine carbohydrate specific effects on in vitro immune modulation exemplified by β-glucans by Rieder, Anne, Grimmer, Stine, L. Aachmann, Finn, Westereng, Bjørge, Kolset, Svein Olav, Knutsen, Svein Halvor

“…► Contaminants in purified carbohydrate preparations can cause confounding effects. ► Proper validation of possible immune-stimulating effects is therefore…”
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Class IV Lasso Peptides Synergistically Induce Proliferation of Cancer Cells and Sensitize Them to Doxorubicin by Guerrero-Garzón, Jaime Felipe, Madland, Eva, Zehl, Martin, Singh, Madhurendra, Rezaei, Shiva, Aachmann, Finn L., Courtade, Gaston, Urban, Ernst, Rückert, Christian, Busche, Tobias, Kalinowski, Jörn, Cao, Yan-Ru, Jiang, Yi, Jiang, Cheng-lin, Selivanova, Galina, Zotchev, Sergey B.

“…Heterologous expression of a biosynthesis gene cluster from Amycolatopsis sp. resulted in the discovery of two unique class IV lasso peptides, felipeptins A1…”
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NMR and Fluorescence Spectroscopies Reveal the Preorganized Binding Site in Family 14 Carbohydrate-Binding Module from Human Chitotriosidase by Madland, Eva, Crasson, Oscar, Vandevenne, Maryléne, Sørlie, Morten, Aachmann, Finn L

“…Carbohydrate-binding modules (CBM) play important roles in targeting and increasing the concentration of carbohydrate active enzymes on their substrates. Using…”
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The carbohydrate-binding module and linker of a modular lytic polysaccharide monooxygenase promote localized cellulose oxidation by Courtade, Gaston, Forsberg, Zarah, Heggset, Ellinor B., Eijsink, Vincent G.H., Aachmann, Finn L.

“…Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that catalyze the oxidative cleavage of polysaccharides such as cellulose and chitin,…”
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