Search Results - "AZUMA, HARUHITO"

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation by Iske, Jasper, Seyda, Midas, Heinbokel, Timm, Maenosono, Ryoichi, Minami, Koichiro, Nian, Yeqi, Quante, Markus, Falk, Christine S., Azuma, Haruhito, Martin, Friederike, Passos, João F., Niemann, Claus U., Tchkonia, Tamara, Kirkland, James L., Elkhal, Abdallah, Tullius, Stefan G.

“…Older organs represent an untapped potential to close the gap between demand and supply in organ transplantation but are associated with age-specific responses…”
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Current treatment strategies for advanced prostate cancer by Komura, Kazumasa, Sweeney, Christopher J, Inamoto, Teruo, Ibuki, Naokazu, Azuma, Haruhito, Kantoff, Philip W

“…During the past decade, treatment strategies for patients with advanced prostate cancer involving stage IV (T4N0M0, N1M0 or M1) hormone‐sensitive prostate…”
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CRISPR Screen Contributes to Novel Target Discovery in Prostate Cancer by Tsujino, Takuya, Komura, Kazumasa, Inamoto, Teruo, Azuma, Haruhito

“…Prostate cancer (PCa) is one of the common malignancies in male adults. Recent advances in omics technology, especially in next-generation sequencing, have…”
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Clinical Practice Guidelines for Bladder Cancer 2019 update by the Japanese Urological Association: Summary of the revision by Matsumoto, Hiroaki, Shiraishi, Koji, Azuma, Haruhito, Inoue, Keiji, Uemura, Hirotsugu, Eto, Masatoshi, Ohyama, Chikara, Ogawa, Osamu, Kikuchi, Eiji, Kitamura, Hiroshi, Shinohara, Nobuo, Takahashi, Satoru, Tsuzuki, Toyonori, Nakagawa, Masayuki, Narumi, Yoshifumi, Nishiyama, Hiroyuki, Habuchi, Tomonori, Hinotsu, Shiro, Fujii, Yasuhisa, Fujimoto, Kiyohide, Fujimoto, Hiroyuki, Mizowaki, Takashi, Matsuyama, Hideyasu

“…Objectives Despite just a 4‐year interval from the last version (2015) of the Clinical Practice Guidelines for Bladder Cancer, several dramatic paradigm shifts…”
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Editorial Comment to Day‐case catheterless and drainless minimal‐access pyeloplasty in adults: A single‐center experience of 13 years by Inamoto, Teruo, Azuma, Haruhito

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Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents by Komura, Kazumasa, Inamoto, Teruo, Tsujino, Takuya, Matsui, Yusuke, Konuma, Tsuyoshi, Nishimura, Kazuki, Uchimoto, Taizo, Tsutsumi, Takeshi, Matsunaga, Tomohisa, Maenosono, Ryoichi, Yoshikawa, Yuki, Taniguchi, Kohei, Tanaka, Tomohito, Uehara, Hirofumi, Hirata, Koichi, Hirano, Hajime, Nomi, Hayahito, Hirose, Yoshinobu, Ono, Fumihito, Azuma, Haruhito

“…There has been accumulating evidence for the clinical benefit of chemoradiation therapy (CRT), whereas mechanisms in CRT-recurrent clones derived from the…”
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Editorial Comment to Obese men undergoing radical prostatectomy: Is robotic or retropubic better to limit positive surgical margins? Results from SEARCH by Inamoto, Teruo, Azuma, Haruhito

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Clinical parameters of therapeutic apheresis induction in clinically amyopathic dermatomyositis patients with rapid progressive interstitial lung disease by Kagitani, Maki, Nomi, Hayahito, Azuma, Haruhito

“…Introduction The purpose of this study is to clarify the clinical parameters of therapeutic apheresis (TA) induction in clinically amyopathic dermatomyositis…”
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Comparison of reduced field-of-view DWI and full field-of view DWI for the differentiation between non-muscle invasive bladder cancer and muscle invasive bladder cancer using VI-RADS by Juri, Hiroshi, Higashiyama, Akira, Yamamoto, Kiyohito, Narumi, Yoshifumi, Azuma, Haruhito, Yamamoto, Kazuhiro, Osuga, Keigo

“…Purpose To evaluate whether reduced field-of-view (rFOV) DWI sequence improves the differentiation between non-muscle-invasive bladder cancer (NMIBC) and…”
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‘Trifecta’ outcomes of robot-assisted partial nephrectomy: a large Japanese multicenter study by Furukawa, Junya, Kanayama, Hiroomi, Azuma, Haruhito, Inoue, Keiji, Kobayashi, Yasuyuki, Kashiwagi, Akira, Segawa, Takehiko, Takahashi, Yoshihito, Horie, Shigeo, Ogawa, Osamu, Takenaka, Atsushi, Shiroki, Ryoichi, Tanabe, Kazunari, Fujisawa, Masato

“…Objective The objective of this study was to evaluate the early surgical outcomes of robot-assisted partial nephrectomy (RAPN) for small renal masses in a…”
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Boron neutron capture therapy for urological cancers by Takahara, Kiyoshi, Miyatake, Shin‐Ichi, Azuma, Haruhito, Shiroki, Ryoichi

“…Boron neutron capture therapy is based on a nuclear reaction between the nonradioactive isotope boron‐10 and either low‐energy thermal neutrons or high‐energy…”
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Editorial Comment to Prognostic significance of common preoperative laboratory variables in penile squamous cell carcinoma by Inamoto, Teruo, Azuma, Haruhito

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CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer by Tsujino, Takuya, Takai, Tomoaki, Hinohara, Kunihiko, Gui, Fu, Tsutsumi, Takeshi, Bai, Xiao, Miao, Chenkui, Feng, Chao, Gui, Bin, Sztupinszki, Zsofia, Simoneau, Antoine, Xie, Ning, Fazli, Ladan, Dong, Xuesen, Azuma, Haruhito, Choudhury, Atish D., Mouw, Kent W., Szallasi, Zoltan, Zou, Lee, Kibel, Adam S., Jia, Li

“…Prostate cancer harboring BRCA1/2 mutations are often exceptionally sensitive to PARP inhibitors. However, genomic alterations in other DNA damage response…”
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Editorial Comment to C‐reactive protein can be used to predict the therapeutic effects of nivolumab in patients with metastatic renal cell carcinoma by Inamoto, Teruo, Azuma, Haruhito

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MicroRNA‐143/Musashi‐2/KRAS cascade contributes positively to carcinogenesis in human bladder cancer by Tsujino, Takuya, Sugito, Nobuhiko, Taniguchi, Kohei, Honda, Ryo, Komura, Kazumasa, Yoshikawa, Yuki, Takai, Tomoaki, Minami, Koichiro, Kuranaga, Yuki, Shinohara, Haruka, Tokumaru, Yoshihisa, Heishima, Kazuki, Inamoto, Teruo, Azuma, Haruhito, Akao, Yukihiro

“…It has been well established that microRNA (miR)‐143 is downregulated in human bladder cancer (BC). Recent precision medicine has shown that mutations in BC…”
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The potential of Senolytics in transplantation by Matsunaga, Tomohisa, Iske, Jasper, Schroeter, Andreas, Azuma, Haruhito, Zhou, Hao, Tullius, Stefan G.

“…•Characterizing the clinical relevance of old organs for transplantation.•The impact of aging on graft immunogenicity and transplant outcomes.•The potential of…”
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Synthetic miR-143 Exhibited an Anti-Cancer Effect via the Downregulation of K-RAS Networks of Renal Cell Cancer Cells In Vitro and In Vivo by Takai, Tomoaki, Tsujino, Takuya, Yoshikawa, Yuki, Inamoto, Teruo, Sugito, Nobuhiko, Kuranaga, Yuki, Heishima, Kazuki, Soga, Tomoyoshi, Hayashi, Kotaro, Miyata, Kanjiro, Kataoka, Kazunori, Azuma, Haruhito, Akao, Yukihiro

“…To understand the role of RAS-signaling networks in the pathogenesis of renal cell carcisnoma, we clarified the relationship between miR-143 and RAS. The…”
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Editorial Comment from Dr Inamoto and Dr Azuma to Preclinical orthotopic xenograft model of renal pelvis cancer in which cancer growth could be traced by an in vivo imaging system by Inamoto, Teruo, Azuma, Haruhito

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Efficacy and Safety of Bladder Preservation Therapy in Combination with Atezolizumab and Radiation Therapy (BPT-ART) for Invasive Bladder Cancer: Interim Analysis from a Multicenter, Open-label, Prospective Phase 2 Trial by Kimura, Tomokazu, Ishikawa, Hitoshi, Nagumo, Yoshiyuki, Sekino, Yuta, Kageyama, Yukio, Ushijima, Hiroki, Kawai, Taketo, Yamashita, Hideomi, Azuma, Haruhito, Nihei, Keiji, Takemura, Masae, Hashimoto, Koichi, Maruo, Kazushi, Tsuzuki, Toyonori, Nishiyama, Hiroyuki

“…To evaluate the safety and pathologic complete response (pCR) rate of radiation therapy with atezolizumab as bladder-preserving therapy for invasive bladder…”
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microRNA-145 Mediates the Inhibitory Effect of Adipose Tissue-Derived Stromal Cells on Prostate Cancer by Takahara, Kiyoshi, Ii, Masaaki, Inamoto, Teruo, Nakagawa, Takatoshi, Ibuki, Naokazu, Yoshikawa, Yuki, Tsujino, Takuya, Uchimoto, Taizo, Saito, Kenkichi, Takai, Tomoaki, Tanda, Naoki, Minami, Koichiro, Uehara, Hirofumi, Komura, Kazumasa, Hirano, Hajime, Nomi, Hayahito, Kiyama, Satoshi, Asahi, Michio, Azuma, Haruhito

“…Adipose-derived stromal cell (ASC), known as one of the mesenchymal stem cells (MSCs), is a promising tool for regenerative medicine; however, the effect of…”
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