Search Results - "AXELROD, Douglas W"
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Optimized clinical performance of growth hormone with an expanded genetic code
Published in Proceedings of the National Academy of Sciences - PNAS (31-05-2011)“…The ribosomal incorporation of nonnative amino acids into polypeptides in living cells provides the opportunity to endow therapeutic proteins with unique…”
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FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents
Published in Diabetes (New York, N.Y.) (01-02-2012)“…Fibroblast growth factor 21 (FGF21) mitigates many of the pathogenic features of type 2 diabetes, despite a short circulating half-life. PEGylation is a proven…”
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Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21
Published in Journal of peptide science (01-06-2012)“…The identification of leptin as a mediator of body weight regulation provided much initial excitement for the treatment of obesity. Unfortunately, leptin…”
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Effects of Risedronate Treatment on Vertebral and Nonvertebral Fractures in Women With Postmenopausal Osteoporosis: A Randomized Controlled Trial
Published in JAMA : the journal of the American Medical Association (13-10-1999)“…CONTEXT Risedronate, a potent bisphosphonate, has been shown to be effective in the treatment of Paget disease of bone and other metabolic bone diseases but,…”
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Risedronate therapy prevents corticosteroid‐induced bone loss : A twelve‐month, multicenter, randomized, double‐blind, placebo‐controlled, parallel‐group study
Published in Arthritis and rheumatism (01-11-1999)“…Objective Risedronate, a new pyridinyl bisphosphonate, is a potent antiresorptive bone agent. This study examines the safety and efficacy of daily, oral…”
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Journal Article Conference Proceeding -
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Tribute to Harold M. Frost M.D
Published in Journal of musculoskeletal & neuronal interactions (01-12-2004)Get full text
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Risedronate in Paget's disease: preliminary results of a multicenter study
Published in Seminars in arthritis and rheumatism (01-02-1994)Get more information
Journal Article