Search Results - "AVULA, Rajeswari"
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Analysis of Cell-Free DNA to Assess Risk of Tumoremia Following Endoscopic Ultrasound Fine-Needle Aspiration of Pancreatic Adenocarcinomas
Published in Clinical gastroenterology and hepatology (01-10-2018)“…Cellular and nuclear material from tumors disseminates into the bloodstream (tumoremia), but it is not clear whether medical procedures cause release of this…”
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Loss of HSulf-1 Up-regulates Heparin-binding Growth Factor Signaling in Cancer
Published in The Journal of biological chemistry (20-06-2003)“…Emerging data suggest that signaling by heparin-binding growth factors is influenced by the sulfation state of N -acetylglucosamine residues of heparan sulfate…”
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Alternative method of allelic discrimination
Published in BioTechniques (01-08-2014)“…5' nuclease assays for allelic discrimination use both a wild-type and a mutant probe. Here we present a new method for genotyping by 5' nuclease assays that…”
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Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer
Published in Oncogene (28-07-2005)“…Epigenetic silencing by hypermethylation of CpGs represents a mechanism of inactivation of tumor suppressors. Here we report on the cloning of a novel…”
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Studies of Humoral Immunity to Preprohypocretin in Human Leukocyte Antigen DQB10602–Positive Narcoleptic Subjects with Cataplexy
Published in Biological psychiatry (1969) (15-09-2005)“…Canine models for narcolepsy have mutations of the hypocretin receptor 2 gene, and preprohypocretin knockout murine lines exhibit narcoleptic-like behaviors…”
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Concordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type
Published in Human immunology (01-08-2020)“…We explored the feasibility of obtaining accurate HLA type using pre-existing NGS data not generated for HLA purposes. 83 exomes and 500 targeted NGS…”
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Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death: Verification of Next-Generation Sequencing Panels for Hereditary Cardiovascular Conditions Using Formalin-Fixed Paraffin-Embedded Tissues and Dried Blood Spots
Published in Circulation. Cardiovascular genetics (01-12-2017)“…Postmortem genetic testing for heritable cardiovascular (CV) disorders is often lacking because ideal specimens (ie, whole blood) are not retained routinely at…”
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Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death
Published in Circulation. Cardiovascular genetics (01-12-2017)“…Background—Postmortem genetic testing for heritable cardiovascular (CV) disorders is often lacking because ideal specimens (ie, whole blood) are not retained…”
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Abstract 505: Optimized 7-Plex cell-free DNA assay for clinically relevant KRAS mutations in colorectal cancer
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Background: KRAS gene mutations are present in approximately 40% of colorectal adenocarcinomas and predict for nonresponse to the anti-epidermal…”
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SULT1A1, CYP2C19 and disease-free survival in early breast cancer patients receiving tamoxifen
Published in Pharmacogenomics (01-11-2011)“…Tamoxifen biotransformation to endoxifen, a potent antiestrogen, is catalyzed by CYP2D6. In addition, CYP2C19 and SULT1A1 have also been implicated in the…”
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Genetic analysis of early- versus late-stage ovarian tumors
Published in Cancer research (Chicago, Ill.) (01-08-2001)“…In the United States, ovarian cancer is the fourth most common cause of cancer-related deaths among women. The most important prognostic factor for this cancer…”
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Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization
Published in Cancer research (Chicago, Ill.) (2002)“…To identify novel tumor suppressor genes involved in ovarian carcinogenesis, we generated four down-regulated suppression subtraction cDNA libraries from two…”
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Analysis of hypocretin (orexin) antibodies in patients with narcolepsy
Published in Sleep (New York, N.Y.) (01-04-2005)“…We tested the hypothesis that patients with narcolepsy have serum antibodies specific for preprohypocretin and its derivatives. We tested sera from strictly…”
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Correlation of CYP2B6 , CYP2C19 , ABCC4 and SOD2 genotype with outcomes in allogeneic blood and marrow transplant patients
Published in Leukemia research (01-01-2012)“…Abstract CYP2B6 , CYP2C19 , ABCC4 , and SOD2 have been implicated in adverse drug reactions and survival after cyclophosphamide (CPA) treatment. 110 BMT…”
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