Search Results - "AVELLAR, Maria Christina W"
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β-defensins and the epididymis: contrasting influences of prenatal, postnatal, and adult scenarios
Published in Asian journal of andrology (01-03-2016)“…β-defensins are components of host defense, with antimicrobial and pleiotropic immuno-modulatory properties. Research over the last 15 years has demonstrated…”
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Lipopolysaccharide and lipotheicoic acid differentially modulate epididymal cytokine and chemokine profiles and sperm parameters in experimental acute epididymitis
Published in Scientific reports (08-01-2018)“…Bacterial infections are the most prevalent etiological factors of epididymitis, a commonly diagnosed inflammatory disease in the investigation of male…”
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Testosterone Induces Vascular Smooth Muscle Cell Migration by NADPH Oxidase and c-Src–Dependent Pathways
Published in Hypertension (Dallas, Tex. 1979) (01-06-2012)“…Testosterone has been implicated in vascular remodeling associated with hypertension. Molecular mechanisms underlying this are elusive, but oxidative stress…”
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Editorial: Updates and New Concepts in Regulation of Proinflammatory Gene Expression by Steroid Hormones
Published in Frontiers in endocrinology (Lausanne) (27-04-2018)Get full text
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Changes in Estrogen Receptor ERβ (ESR2) Expression without Changes in the Estradiol Levels in the Prostate of Aging Rats
Published in PloS one (06-07-2015)“…Although the prostate is androgen-dependent, it is also influenced by estrogens, which act via the estrogen receptors ERα and ERβ. In the prostate, ERβ is…”
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Activation of Toll-Like Receptor 4 (TLR4) by In Vivo and In Vitro Exposure of Rat Epididymis to Lipopolysaccharide from Escherichia Coli
Published in Biology of reproduction (01-12-2008)“…This study provides the first evidence that rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia…”
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Epididymal protease inhibitor (EPPIN) is differentially expressed in the male rat reproductive tract and immunolocalized in maturing spermatozoa
Published in Molecular reproduction and development (01-12-2012)“…EPPIN (epididymal protease inhibitor; SPINLW1), an antimicrobial cysteine‐rich protein containing both Kunitz and whey acidic protein (WAP)‐type four disulfide…”
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Could the gut microbiota be capable of making individuals more or less susceptible to environmental toxicants?
Published in Toxicology (Amsterdam) (01-03-2024)“…Environmental toxicants are chemical substances capable to impair environmental quality and exert adverse effects on humans and other animals. The main routes…”
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Novel Aspects of the Sperm-Associated Antigen 11 (SPAG11) Gene Organization and Expression in Cattle (Bos taurus)
Published in Biology of reproduction (01-06-2007)“…Beta-defensins are small cationic peptides exhibiting broad spectrum antimicrobial properties. In humans, many beta-defensin genes are located within a cluster…”
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Increased expression of acetylcholine receptors in the diaphragm muscle of mdx mice
Published in Muscle & nerve (01-12-2008)“…The absence of dystrophin in Duchenne muscular dystrophy (DMD) and in the mutant mdx mouse causes muscle degeneration and disruption of the neuromuscular…”
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Epididymal mRNA expression profiles for the protein disulfide isomerase gene family: Modulation by development and androgens
Published in Andrology (Oxford) (01-08-2024)“…The endoplasmic reticulum (ER) is the central hub for protein quality control, where the protein disulfide isomerases (PDIs), encoded by at least 21 genes,…”
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Muscarinic Acetylcholine Receptor Subtypes in the Male Reproductive Tract: Expression and Function in Rat Efferent Ductules and Epididymis
Published in Journal of molecular neuroscience (2010)“…In mammals, at least five different muscarinic acetylcholine receptor subtypes (mAChRs; M 1 –M 5 ) are known to be widely expressed and distributed in…”
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Differential Expression and Antibacterial Activity of Epididymis Protein 2 Isoforms in the Male Reproductive Tract of Human and Rhesus Monkey (Macaca mulatta)
Published in Biology of reproduction (01-11-2004)“…The epididymis protein 2 (EP2) gene, the fusion of two ancestral β-defensin genes, is highly expressed in the epididymis and subject to species-specific…”
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Epididymal embryonic development harbors TLR4/NFKB signaling pathway as a morphogenetic player
Published in Journal of reproductive immunology (01-02-2022)“…[Display omitted] •TLR4/NFKB signaling cascade components are present in developing WD.•TLR4/NFKB signaling is functional in epididymal development.•The TLR4…”
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Lipopolysaccharide-induced epididymitis modifies the transcriptional profile of Wfdc genes in mice
Published in Biology of reproduction (01-01-2021)“…Whey-acidic protein four-disulfide core domain (WFDC) genes display putative roles in innate immunity and fertility. In mice, a locus on chromosome 2 contains…”
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Dissecting EPPIN protease inhibitor domains in sperm motility and fertilizing ability: repercussions for male contraceptive development
Published in Molecular human reproduction (27-11-2021)“…Abstract EPPIN (epididymal protease inhibitor) is a mammalian conserved sperm-binding protein displaying an N-terminal WFDC (whey-acidic protein four-disulfide…”
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A historical summary of the Brazilian Society of Pharmacology and Experimental Therapeutics (SBFTE)
Published in Pharmacological research (01-10-2016)Get full text
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Activation of Toll-Like Receptor 4 (TLR4) by In Vivo and In Vitro Exposure of Rat Epididymis to Lipopolysaccharide from Escherichia Coli1
Published in Biology of reproduction (01-12-2008)“…This study provides the first evidence that rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia…”
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Effects of testosterone on muscarinic acetylcholine receptors in the rat epididymis
Published in Life sciences (1973) (24-06-2005)“…The effect of testosterone on the expression of muscarinic acetylcholine receptor (mAChR) subtypes was studied in the rat epididymis, at mRNA and protein…”
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