Search Results - "AURORA, S. K"

The brain is hyperexcitable in migraine by Aurora, S K, Wilkinson, F

“…Migraine is a very common disorder occurring in 20% of women and 6% of men. Central neuronal hyperexcitability is proposed to be the putative basis for the…”
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OnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 2 trial by Diener, H C, Dodick, D W, Aurora, S K, Turkel, C C, DeGryse, R E, Lipton, R B, Silberstein, S D, Brin, M F

“…This is the second of a pair of studies designed to evaluate the efficacy and safety of onabotulinumtoxinA (BOTOX) for prophylaxis of headaches in adults with…”
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OnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 1 trial by Aurora, S K, Dodick, D W, Turkel, C C, DeGryse, R E, Silberstein, S D, Lipton, R B, Diener, H C, Brin, M F

“…This is the first of a pair of studies designed to assess efficacy, safety and tolerability of onabotulinumtoxinA (BOTOX) as headache prophylaxis in adults…”
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OnabotulinumtoxinA improves quality of life and reduces impact of chronic migraine by LIPTON, R. B, VARON, S. F, NOLAN, M. E, TURKEL, C. C, GROSBERG, B, MCALLISTER, P. J, FREITAG, F, AURORA, S. K, DODICK, D. W, SILBERSTEIN, S. D, DIENER, H. C, DEGRYSE, R. E

“…To assess the effects of treatment with onabotulinumtoxinA (Botox, Allergan, Inc., Irvine, CA) on health-related quality of life (HRQoL) and headache impact in…”
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OnabotulinumtoxinA for chronic migraine: efficacy, safety, and tolerability in patients who received all five treatment cycles in the PREEMPT clinical program by Aurora, S. K., Dodick, D. W., Diener, H.-C., DeGryse, R. E., Turkel, C. C., Lipton, R. B., Silberstein, S. D.

“…Objective Chronic migraine (CM) is a prevalent and disabling neurological disorder. Phase III REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT)…”
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Functional MRI-BOLD of brainstem structures during visually triggered migraine by CAO, Y, AURORA, S. K, NAGESH, V, PATEL, S. C, WELCH, K. M. A

“…Previously, hyperoxia and blood volume increase were reported in the red nucleus and substantia nigra during spontaneous migraine with aura. To further…”
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Transcranial magnetic stimulation confirms hyperexcitability of occipital cortex in migraine by AURORA, S. K, AHMAD, B. K, WELCH, K. M. A, BHARDHWAJ, P, RAMADAN, N. M

“…We hypothesized that the hyperexcitability of occipital cortex neurons may predispose migraine subjects to develop spreading depression, the putative basis of…”
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Intranasal sumatriptan in cluster headache: Randomized placebo-controlled double-blind study by VAN VLIET, J. A, BAHRA, A, MARTIN, V, RAMADAN, N, AURORA, S. K, MATHEW, N. T, FERRARI, M. D, GOADSBY, P. J

“…Current evidence-based acute treatments of cluster headache are limited to oxygen inhalation and subcutaneous sumatriptan. Intranasal sumatriptan is a new…”
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Is chronic migraine one end of a spectrum of migraine or a separate entity? by Aurora, S K

“…Chronic migraine is associated with abnormalities in the periaqueductal grey that may be progressive. The condition is also associated with a greater degree of…”
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History of childhood maltreatment is associated with comorbid depression in women with migraine by TIETJEN, G. E, BRANDES, J. L, UTLEY, C, KHUDER, S. A, DIGRE, K. B, BAGGALEY, S, MARTIN, V. T, RECOBER, A, GEWEKE, L. O, HAFEEZ, F, AURORA, S. K, HERIAL, N. A

“…A bidirectional relationship between migraine and depression suggests a neurobiological link. Adverse experiences, particularly childhood maltreatment, may…”
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The Occipital Cortex Is Hyperexcitable in Migraine: Experimental Evidence by Aurora, SK, Cao, Y., Bowyer, SM, Welch, K.M.A.

“…Objectives.—Threshold for generation of magnetophosphenes has been reported to be lower in migraine. We compared the threshold for eliciting phosphenes by…”
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High prevalence of somatic symptoms and depression in women with disabling chronic headache by TIETJEN, G. E, BRANDES, J. L, UTLEY, C, KHUDER, S. A, DIGRE, K. B, BAGGALEY, S, MARTIN, V, RECOBER, A, GEWEKE, L. O, HAFEEZ, F, AURORA, S. K, HERIAL, N. A

“…To better define, in women with headache, the relationship of depression and somatic symptoms to headache, characterized by diagnoses, frequency, and…”
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Periaqueductal Gray Matter Dysfunction in Migraine: Cause or the Burden of Illness? by Welch, K.M.A., Nagesh, Vijaya, Aurora, Sheena K., Gelman, Neil

“…Objective.—The periaqueductal gray matter (PAG) is at the center of a powerful descending antinociceptive neuronal network. We studied iron homeostasis in the…”
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Positive response to galcanezumab following treatment failure to onabotulinumtoxinA in patients with migraine: post hoc analyses of three randomized double‐blind studies by Ailani, J., Pearlman, E., Zhang, Q., Nagy, A. J., Schuh, K., Aurora, S. K.

“…Background and purpose Humanized monoclonal antibody galcanezumab, which binds to calcitonin‐gene‐related peptide, has shown efficacy for episodic and chronic…”
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Efficacy of galcanezumab in patients with episodic migraine and a history of preventive treatment failure: results from two global randomized clinical trials by Ruff, D. D., Ford, J. H., Tockhorn‐Heidenreich, A., Stauffer, V. L., Govindan, S., Aurora, S. K., Terwindt, G. M., Goadsby, P. J.

“…Background and purpose The efficacy of galcanezumab, a monoclonal antibody for migraine prevention, has been demonstrated in two pivotal trials in patients…”
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Topiramate modulates excitability of the occipital cortex when measured by transcranial magnetic stimulation by Aurora, S K, Barrodale, P M, Vermaas, A R, Rudra, C B

“…The aim of this study was to measure differences in occipital cortex excitability in migraineurs before and after administration of topiramate. We have…”
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Magnetoencephalographic fields from patients with spontaneous and induced migraine aura by Bowyer, Susan M., Aurora, Sheena K., Moran, John E., Tepley, Norman, Welch, K. M. A.

“…We investigate and characterize the magnetoencephalographic waveforms from patients during spontaneous and visually induced migraine aura. Direct current…”
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Self-reported Photophobic Symptoms in Migraineurs and Controls Are Reliable and Predict Diagnostic Category Accurately by Mulleners, W.M., Aurora, S.K., Chronicle, E.P., Stewart, R., Gopal, S., Koehler, P.J.

“…Objectives.—To assess the reliability of self‐reported photophobia across different patient populations and to examine how visual stress thresholds and…”
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Response to ‘Do different treatment strategies of galcanezumab have similar effect on migraine?’ by Goadsby, P. J., Terwindt, G. M., Ruff, D. D., Ford, J. H., Tockhorn‐Heidenreich, A., Stauffer, V. L., Govindan, S., Aurora, S. K.

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The cortical silent period is shortened in migraine with aura by Aurora, S K, al-Sayeed, F, Welch, K M

“…Central neuronal hyperexcitability may be the physiological disturbance that predisposes subjects to migraine attacks. To test this hypothesis, we studied the…”
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