Search Results - "AURANEN, Kari"

The fundamental link between pneumococcal carriage and disease by Simell, Birgit, Auranen, Kari, Käyhty, Helena, Goldblatt, David, Dagan, Ron, O'Brien, Katherine L

“…Streptococcus pneumoniae (pneumococcus) is a major cause of worldwide mortality and morbidity, and to a large extent is vaccine-preventable. Nasopharyngeal…”
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Exposure misclassification bias in the estimation of vaccine effectiveness by Baum, Ulrike, Kulathinal, Sangita, Auranen, Kari

“…In epidemiology, a typical measure of interest is the risk of disease conditional upon exposure. A common source of bias in the estimation of risks and risk…”
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Effects of physical activity intervention on 24-h movement behaviors: a compositional data analysis by Pasanen, Jesse, Leskinen, Tuija, Suorsa, Kristin, Pulakka, Anna, Virta, Joni, Auranen, Kari, Stenholm, Sari

“…We utilized compositional data analysis (CoDA) to study changes in the composition of the 24-h movement behaviors during an activity tracker based physical…”
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Efficacy and effectiveness of case isolation and quarantine during a growing phase of the COVID-19 epidemic in Finland by Auranen, Kari, Shubin, Mikhail, Erra, Elina, Isosomppi, Sanna, Kontto, Jukka, Leino, Tuija, Lukkarinen, Timo

“…Based on data collected as part of the contact tracing activity of the City of Helsinki Epidemiological Operations Unit, we evaluated the efficacy and…”
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Social contacts and mixing patterns relevant to the spread of infectious diseases by Mossong, Joël, Hens, Niel, Jit, Mark, Beutels, Philippe, Auranen, Kari, Mikolajczyk, Rafael, Massari, Marco, Salmaso, Stefania, Tomba, Gianpaolo Scalia, Wallinga, Jacco, Heijne, Janneke, Sadkowska-Todys, Malgorzata, Rosinska, Magdalena, Edmunds, W John

“…Mathematical modelling of infectious diseases transmitted by the respiratory or close-contact route (e.g., pandemic influenza) is increasingly being used to…”
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Optimal serotype compositions for Pneumococcal conjugate vaccination under serotype replacement by Nurhonen, Markku, Auranen, Kari

“…Pneumococcal conjugate vaccination has proved highly effective in eliminating vaccine-type pneumococcal carriage and disease. However, the potential adverse…”
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Underreporting of SARS-CoV-2 infections during the first wave of the 2020 COVID-19 epidemic in Finland-Bayesian inference based on a series of serological surveys by Nieminen, Tuomo A, Auranen, Kari, Kulathinal, Sangita, Härkänen, Tommi, Melin, Merit, Palmu, Arto A, Jokinen, Jukka

“…In Finland, the first wave of the COVID-19 epidemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) took place from March to June…”
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Changing epidemiology of methicillin-resistant Staphylococcus aureus in a low endemicity area—new challenges for MRSA control by Junnila, Jenna, Hirvioja, Tiina, Rintala, Esa, Auranen, Kari, Rantakokko-Jalava, Kaisu, Silvola, Jaakko, Lindholm, Laura, Gröndahl-Yli-Hannuksela, Kirsi, Marttila, Harri, Vuopio, Jaana

“…The incidence of methicillin-resistant Staphylococcus aureus (MRSA) has increased sharply in Hospital District of Southwest Finland (HD). To understand reasons…”
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Pneumococcal transmission and disease in silico: a microsimulation model of the indirect effects of vaccination by Nurhonen, Markku, Cheng, Allen C, Auranen, Kari

“…The degree and time frame of indirect effects of vaccination (serotype replacement and herd immunity) are key determinants in assessing the net effectiveness…”
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Revealing the True Incidence of Pandemic A(H1N1)pdm09 Influenza in Finland during the First Two Seasons - An Analysis Based on a Dynamic Transmission Model by Shubin, Mikhail, Lebedev, Artem, Lyytikäinen, Outi, Auranen, Kari

“…The threat of the new pandemic influenza A(H1N1)pdm09 imposed a heavy burden on the public health system in Finland in 2009-2010. An extensive vaccination…”
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Impact and effectiveness of a conjugate vaccine against invasive pneumococcal disease in Finland - a modelling approach by Rinta-Kokko, Hanna, Nurhonen, Markku, Auranen, Kari

“…The evaluation of the public health impact of a vaccination program is essential in monitoring its policy relevance. Vaccine impact (VI) is usually assessed in…”
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Increased risk for dementia in neurofibromatosis type 1 by Kallionpää, Roope A., Valtanen, Mikko, Auranen, Kari, Uusitalo, Elina, Rinne, Juha O., Peltonen, Sirkku, Peltonen, Juha

“…Purpose To determine the risk for dementia in neurofibromatosis type 1 (NF1) using a Finnish nationwide cohort of individuals with NF1, and data from national…”
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Whole genome sequencing reveals new links between spa t172/CC59 methicillin-resistant Staphylococcus aureus cases in low-endemicity region of Southwest Finland, 2007‒2016 by Silvola, Jaakko, Gröndahl-Yli-Hannuksela, Kirsi, Hirvioja, Tiina, Rantakokko-Jalava, Kaisu, Rintala, Esa, Auranen, Kari, Junnila, Jenna, Marttila, Harri, Lindholm, Laura, Vuopio, Jaana

“…Methicillin-resistant Staphylococcus aureus (MRSA) rates have remained relatively low in Finland. In Southwest Finland, however, annual MRSA incidence…”
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Surveillance of Circulating Bordetella pertussis Strains in Europe during 1998 to 2015 by Barkoff, Alex-Mikael, Mertsola, Jussi, Pierard, Denis, Dalby, Tine, Hoegh, Silje Vermedal, Guillot, Sophie, Stefanelli, Paola, van Gent, Marjolein, Berbers, Guy, Vestrheim, Didrik F, Greve-Isdahl, Margrethe, Wehlin, Lena, Ljungman, Margaretha, Fry, Norman K, Markey, Kevin, Auranen, Kari, He, Qiushui

“…One reason for increased pertussis incidence is the adaptation of to vaccine-induced immunity by modulating its genomic structure. This study, EUpert IV,…”
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Simulations for designing and interpreting intervention trials in infectious diseases by Halloran, M Elizabeth, Auranen, Kari, Baird, Sarah, Basta, Nicole E, Bellan, Steven E, Brookmeyer, Ron, Cooper, Ben S, DeGruttola, Victor, Hughes, James P, Lessler, Justin, Lofgren, Eric T, Longini, Ira M, Onnela, Jukka-Pekka, Özler, Berk, Seage, George R, Smith, Thomas A, Vespignani, Alessandro, Vynnycky, Emilia, Lipsitch, Marc

“…Interventions in infectious diseases can have both direct effects on individuals who receive the intervention as well as indirect effects in the population. In…”
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New Pneumococcal Carriage Acquired in Association with Acute Respiratory Infection Is Prone to Cause Otitis Media by Auranen, Kari, Syrjänen, Ritva, Leino, Tuija, Kilpi, Terhi

“…For considering vaccine-prevention of pneumococcal acute otitis media (PncAOM), relationships between pneumococcal carriage, respiratory infection and PncAOM…”
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Between-Strain Competition in Acquisition and Clearance of Pneumococcal Carriage—Epidemiologic Evidence From a Longitudinal Study of Day-Care Children by Auranen, Kari, Mehtälä, Juha, Tanskanen, Antti, S. Kaltoft, Margit

“…The state of pneumococcal carriage—that is, pneumococcal colonization in the nasopharynx of healthy persons—represents a reservoir for the spread of…”
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Impact of vaccination on 14 high-risk HPV type infections: a mathematical modelling approach by Vänskä, Simopekka, Auranen, Kari, Leino, Tuija, Salo, Heini, Nieminen, Pekka, Kilpi, Terhi, Tiihonen, Petri, Apter, Dan, Lehtinen, Matti

“…The development of high-risk human papillomavirus (hrHPV) infection to cervical cancer is a complicated process. We considered solely hrHPV infections, thus…”
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Serotype-Specific Hyporesponsiveness to Pneumococcal Conjugate Vaccine in Infants Carrying Pneumococcus at the Time of Vaccination by Väkeväinen, Merja, PhD, Soininen, Anu, PhD, Lucero, Marilla, MD, PhD, Nohynek, Hanna, MD, PhD, Auranen, Kari, PhD, Mäkelä, P. Helena, MD, PhD, Williams, Gail, PhD, Käyhty, Helena, PhD

“…Objective To determine whether pneumococcal carriage at the time of 11-valent pneumococcal conjugate vaccine (PCV-11) administration interferes with immune…”
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18F-FDG-PET/CT based total metabolic tumor volume change during neoadjuvant chemotherapy predicts outcome in advanced epithelial ovarian cancer by Vallius, Tuulia, Hynninen, Johanna, Kemppainen, Jukka, Alves, Victor, Auranen, Kari, Matomäki, Jaakko, Oksa, Sinikka, Virtanen, Johanna, Grénman, Seija, Auranen, Annika, Seppänen, Marko

“…Objective To evaluate the predictive potential of total metabolic tumor volume (MTV) reduction during neoadjuvant chemotherapy (NACT) with 18 F–FDG-PET/CT in…”
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