Search Results - "AUGER, Francois A"

Anticancer properties of chitosan on human melanoma are cell line dependent by Gibot, Laure, Chabaud, Stéphane, Bouhout, Sara, Bolduc, Stéphane, Auger, François A, Moulin, Véronique J

“…Chitosan, a natural macromolecule, is widely used in medical and pharmaceutical fields because of its distinctive properties such as bactericide, fungicide and…”
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Immune tolerance of tissue-engineered skin produced with allogeneic or xenogeneic fibroblasts and syngeneic keratinocytes grafted on mice by Goyer, Benjamin, Larouche, Danielle, Kim, Dong Hyun, Veillette, Noémie, Pruneau, Virgile, Bernier, Vincent, Auger, François A., Germain, Lucie

“…[Display omitted] Organs are needed for the long-term replacement of diseased or wounded tissues. Various technologies based on cells seeded in synthetic or…”
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Speeding up the production of clinical-grade skin substitutes using off-the-shelf decellularized self-assembled dermal matrices by Magne, Brice, Demers, Anabelle, Savard, Étienne, Lemire-Rondeau, Marika, Veillette, Noémie, Pruneau, Virgile, Guignard, Rina, Morissette, Amélie, Larouche, Danielle, Auger, François A., Germain, Lucie

“…Patients with deep and extensive wounds need urgent skin coverage to re-establish the cutaneous barrier that prevents life-threatening infections and…”
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Human adipose-derived stromal cells for the production of completely autologous self-assembled tissue-engineered vascular substitutes by Vallières, Karine, Laterreur, Véronique, Tondreau, Maxime Y., Ruel, Jean, Germain, Lucie, Fradette, Julie, Auger, François A.

“…[Display omitted] There is a clinical need for small-diameter vascular substitutes, notably for coronary and peripheral artery bypass procedures since these…”
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Mechanical properties of endothelialized fibroblast-derived vascular scaffolds stimulated in a bioreactor by Tondreau, Maxime Y., Laterreur, Véronique, Gauvin, Robert, Vallières, Karine, Bourget, Jean-Michel, Lacroix, Dan, Tremblay, Catherine, Germain, Lucie, Ruel, Jean, Auger, François A.

“…[Display omitted] There is an ongoing clinical need for tissue-engineered small-diameter (<6mm) vascular grafts since clinical applications are restricted by…”
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Peptide grafting on intraosseous transcutaneous amputation prostheses to promote sealing with skin cells: Potential to limit infections by Ghribi, Nawel, Guay‐Bégin, Andrée‐Anne, Bilem, Ibrahim, Chevallier, Pascale, Auger, François A., Ruel, Jean, Laroche, Gaétan

“…The long‐term success of intraosseous transcutaneous amputation prostheses (ITAPs) mainly relies on dermal attachment of skin cells to the implant. Otherwise,…”
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Biofabrication and preclinical evaluation of a large-sized human self-assembled skin substitute by Kawecki, Fabien, Mayrand, Dominique, Ayoub, Akram, Attiogbe, Émilie, Germain, Lucie, Auger, François A, Moulin, Véronique J

“…Severe skin burns are widely treated using split-thickness skin autografts. However, the accessibility of the donor site may be limited depending on the size…”
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Progress in developing a living human tissue-engineered tri-leaflet heart valve assembled from tissue produced by the self-assembly approach by Dubé, Jean, Bourget, Jean-Michel, Gauvin, Robert, Lafrance, Hugues, Roberge, Charles J., Auger, François A., Germain, Lucie

“…The aortic heart valve is constantly subjected to pulsatile flow and pressure gradients which, associated with cardiovascular risk factors and abnormal…”
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In Vivo Evaluation and Imaging of a Bilayered Self-Assembled Skin Substitute Using a Decellularized Dermal Matrix Grafted on Mice by Beaudoin Cloutier, Chanel, Goyer, Benjamin, Perron, Cindy, Guignard, Rina, Larouche, Danielle, Moulin, Véronique J, Germain, Lucie, Gauvin, Robert, Auger, François A

“…As time to final coverage is the essence for better survival outcome in severely burned patients, we have continuously strived to reduce the duration for the…”
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A Cell‐Based Self‐Assembly Approach for the Production of Human Osseous Tissues from Adipose‐Derived Stromal/Stem Cells by Galbraith, Todd, Clafshenkel, William P., Kawecki, Fabien, Blanckaert, Camille, Labbé, Benoit, Fortin, Michel, Auger, François A., Fradette, Julie

“…Achieving optimal bone defect repair is a clinical challenge driving intensive research in the field of bone tissue engineering. Many strategies focus on…”
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Mechanical Stimuli-induced Urothelial Differentiation in a Human Tissue-engineered Tubular Genitourinary Graft by Cattan, Valérie, Bernard, Geneviève, Rousseau, Alexandre, Bouhout, Sara, Chabaud, Stéphane, Auger, François A, Bolduc, Stéphane

“…Abstract Background A challenge in urologic tissue engineering is to obtain well-differentiated urothelium to overcome the complications related to other…”
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Cell Seeding on UV‐C‐Treated 3D Polymeric Templates Allows for Cost‐Effective Production of Small‐Caliber Tissue‐Engineered Blood Vessels by Galbraith, Todd, Roy, Vincent, Bourget, Jean‐Michel, Tsutsumi, Tamao, Picard‐Deland, Maxime, Morin, Jean‐François, Gauvin, Robert, Ismail, Ashraf A., Auger, François A., Gros‐Louis, François

“…There is a strong clinical need to develop small‐caliber tissue‐engineered blood vessels for arterial bypass surgeries. Such substitutes can be engineered…”
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Production of a Bilayered Self-Assembled Skin Substitute Using a Tissue-Engineered Acellular Dermal Matrix by Beaudoin Cloutier, Chanel, Guignard, Rina, Bernard, Geneviève, Gauvin, Robert, Larouche, Danielle, Lavoie, Amélie, Lacroix, Dan, Moulin, Véronique J, Germain, Lucie, Auger, François A

“…Our bilayered self-assembled skin substitutes (SASS) are skin substitutes showing a structure and functionality very similar to native human skin. These…”
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Contribution of Sp1 to Telomerase Expression and Activity in Skin Keratinocytes Cultured With a Feeder Layer by Bisson, Francis, Paquet, Claudie, Bourget, Jean-Michel, Zaniolo, Karine, Rochette, Patrick J., Landreville, Solange, Damour, Odile, Boudreau, François, Auger, François A., Guérin, Sylvain L., Germain, Lucie

“…The growth of primary keratinocytes is improved by culturing them with a feeder layer. The aim of this study was to assess whether the feeder layer increases…”
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Improved Methods to Produce Tissue-Engineered Skin Substitutes Suitable for the Permanent Closure of Full-Thickness Skin Injuries by Larouche, Danielle, Cantin-Warren, Laurence, Desgagné, Maxime, Guignard, Rina, Martel, Israël, Ayoub, Akram, Lavoie, Amélie, Gauvin, Robert, Auger, François A, Moulin, Véronique J, Germain, Lucie

“…There is a clinical need for skin substitutes to replace full-thickness skin loss. Our group has developed a bilayered skin substitute produced from the…”
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Microstructured human fibroblast‐derived extracellular matrix scaffold for vascular media fabrication by Bourget, Jean‐Michel, Laterreur, Véronique, Gauvin, Robert, Guillemette, Maxime D., Miville‐Godin, Caroline, Mounier, Maxence, Tondreau, Maxime Y., Tremblay, Catherine, Labbé, Raymond, Ruel, Jean, Auger, François A., Veres, Teodor, Germain, Lucie

“…In the clinical and pharmacological fields, there is a need for the production of tissue‐engineered small‐diameter blood vessels. We have demonstrated…”
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Tissue-engineered 3D melanoma model with blood and lymphatic capillaries for drug development by Bourland, Jennifer, Fradette, Julie, Auger, François A.

“…While being the rarest skin cancer, melanoma is also the deadliest. To further drug discovery and improve clinical translation, new human cell-based in vitro…”
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The pivotal role of vascularization in tissue engineering by Auger, François A, Gibot, Laure, Lacroix, Dan

“…Vascularization is one of the great challenges that tissue engineering faces in order to achieve sizeable tissue and organ substitutes that contain living…”
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Mechanisms of wound reepithelialization: hints from a tissue‐engineered reconstructed skin to long‐standing questions by LAPLANTE, ALAIN F., GERMAIN, LUCIE, AUGER, FRANCOIS A., MOULIN, VERONIQUE

“…ABSTRACT Wound closure of epithelial tissues must occur efficiently to restore rapidly their barrier function. We have developed a tissue‐engineered…”
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Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function by Guillemette, Maxime D, Cui, Bo, Roy, Emmanuel, Gauvin, Robert, Giasson, Claude J, Esch, Mandy B, Carrier, Patrick, Deschambeault, Alexandre, Dumoulin, Michel, Toner, Mehmet, Germain, Lucie, Veres, Teodor, Auger, Francois A

“…The organization of cells and extracellular matrix (ECM) in native tissues plays a crucial role in their functionality. However, in tissue engineering, cells…”
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