Search Results - "AUERBACH, S"

The sensitivity of transcriptomics BMD modeling to the methods used for microarray data normalization by Mezencev, Roman, Auerbach, Scott S

“…Whole-genome expression data generated by microarray studies have shown promise for quantitative human health risk assessment. While numerous approaches have…”
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Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update by Luks, Andrew M., Auerbach, Paul S., Freer, Luanne, Grissom, Colin K., Keyes, Linda E., McIntosh, Scott E., Rodway, George W., Schoene, Robert B., Zafren, Ken, Hackett, Peter H.

“…To provide guidance to clinicians about best preventive and therapeutic practices, the Wilderness Medical Society (WMS) convened an expert panel to develop…”
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Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome by Auerbach, David S, Jones, Julie, Clawson, Brittany C, Offord, James, Lenk, Guy M, Ogiwara, Ikuo, Yamakawa, Kazuhiro, Meisler, Miriam H, Parent, Jack M, Isom, Lori L

“…Dravet syndrome is a severe form of intractable pediatric epilepsy with a high incidence of SUDEP: Sudden Unexpected Death in epilepsy. Cardiac arrhythmias are…”
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Depressive symptoms and risk of dementia: the Framingham Heart Study by Saczynski, J S, Beiser, A, Seshadri, S, Auerbach, S, Wolf, P A, Au, R

“…Depression may be associated with an increased risk for dementia, although results from population-based samples have been inconsistent. We examined the…”
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The Importance of the Biological Impact of Exposure to the Concept of the Exposome by Dennis, Kristine K, Auerbach, Scott S, Balshaw, David M, Cui, Yuxia, Fallin, Margaret Daniele, Smith, Martyn T, Spira, Avrum, Sumner, Susan, Miller, Gary W

“…The term "exposome" was originally coined in 2005 and defined as the totality of exposures throughout the lifetime. The exposome provides an excellent…”
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Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action by Gusenleitner, Daniel, Auerbach, Scott S, Melia, Tisha, Gómez, Harold F, Sherr, David H, Monti, Stefano

“…Despite an overall decrease in incidence of and mortality from cancer, about 40% of Americans will be diagnosed with the disease in their lifetime, and around…”
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A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics by Mav, Deepak, Shah, Ruchir R, Howard, Brian E, Auerbach, Scott S, Bushel, Pierre R, Collins, Jennifer B, Gerhold, David L, Judson, Richard S, Karmaus, Agnes L, Maull, Elizabeth A, Mendrick, Donna L, Merrick, B Alex, Sipes, Nisha S, Svoboda, Daniel, Paules, Richard S

“…Changes in gene expression can help reveal the mechanisms of disease processes and the mode of action for toxicities and adverse effects on cellular responses…”
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Preparedness explains some differences between Haiti and Nepal’s response to earthquake by Auerbach, Paul S

“…Paul S Auerbach responded to recent disasters in both countries and reflects on why Nepal saw so many fewer deaths and injuries…”
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The last gasp by Auerbach, Paul S, Dr

“…When someone is encased within an icy tomb, survival depends on having a patent airway adjacent to an air pocket, because asphyxia is the leading cause of…”
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Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia by Milstein, Michelle L., Musa, Hassan, Balbuena, Daniela Ponce, Anumonwo, Justus M. B., Auerbach, David S., Furspan, Philip B., Hou, Luqia, Hu, Bin, Schumacher, Sarah M., Vaidyanathan, Ravi, Martens, Jeffrey R., Jalife, José

“…The cardiac electrical impulse depends on an orchestrated interplay of transmembrane ionic currents in myocardial cells. Two critical ionic current mechanisms…”
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Correction: Pannala et al. High-Throughput Transcriptomics Differentiates Toxic versus Non-Toxic Chemical Exposures Using a Rat Liver Model. Int. J. Mol. Sci. 2023, 24 , 17425 by Pannala, Venkat R, Balik-Meisner, Michele R, Mav, Deepak, Phadke, Dhiral P, Scholl, Elizabeth H, Shah, Ruchir R, Auerbach, Scott S, Wallqvist, Anders

“…In the original publication [...]…”
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A Comparison of the TempO-Seq S1500+ Platform to RNA-Seq and Microarray Using Rat Liver Mode of Action Samples by Bushel, Pierre R, Paules, Richard S, Auerbach, Scott S

“…The TempO-Seq platform allows for targeted transcriptomic analysis and is currently used by many groups to perform high-throughput gene expression analysis…”
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Quantitative F18‐fluorodeoxyglucose positron emission tomography accurately characterizes peripheral nerve sheath tumors as malignant or benign by Benz, Matthias R., Czernin, Johannes, Dry, Sarah M., Tap, William D., Allen‐Auerbach, Martin S., Elashoff, David, Phelps, Michael E., Weber, Wolfgang A., Eilber, Fritz C.

“…BACKGROUND: Correct pretreatment classification is critical for optimizing diagnosis and treatment of patients with peripheral nerve sheath tumors (PNSTs). The…”
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Sidney J. Blatt's Contributions to Psychoanalytic Psychology: Introduction to the Special Section by Auerbach, John S.

“…This special section honors the 5-decade career of Sidney J. Blatt and his multiple contributions to psychoanalytic theory, research, and practice. Each of the…”
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Systemic ventricular assist device support in Fontan patients: A report by ACTION by Cedars, Ari, Kutty, Shelby, Danford, David, Schumacher, Kurt, Auerbach, S.R., Bearl, D., Chen, S., Conway, J., Dykes, J.C., Jaworski, N., Joong, A., Lorts, A., Mascio, C.E., Morales, D.L.S., Niebler, R.A., O'Connor, M., Peng, D.M., Philip, J., Reichman, J.R., Rosenthal, D.N., Zafar, F., VanderPluym, C., Villa, C., Zinn, M.

“…The size of the Fontan population with end-stage heart failure is growing. In this population, heart transplantation has been the only option. This study…”
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Marine Envenomation by Hornbeak, Kirsten B., MD, Auerbach, Paul S., MD, MS

“…Venomous aquatic animals are hazardous to swimmers, surfers, divers, and fishermen. Exposures include mild stings, bites, abrasions, and lacerations. Severe…”
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Genetic biomarkers for the risk of seizures in long QT syndrome by Auerbach, David S, McNitt, Scott, Gross, Robert A, Zareba, Wojciech, Dirksen, Robert T, Moss, Arthur J

“…OBJECTIVES:The coprevalence, severity, and biomarkers for seizures and arrhythmias in long QT syndrome (LQTS) remain incompletely understood. METHODS:Using the…”
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Safety and tolerability of the β3 -adrenoceptor agonist mirabegron, for the treatment of overactive bladder: results of a prospective pooled analysis of three 12-week randomised Phase III trials and of a 1-year randomised Phase III trial by Nitti, V W, Chapple, C R, Walters, C, Blauwet, M B, Herschorn, S, Milsom, I, Auerbach, S, Radziszewski, P

“…To evaluate the safety and tolerability of the β3 -adrenoceptor agonist, mirabegron, in patients with overactive bladder (OAB). Tolerability and safety data…”
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Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage by Hsieh, Jui-Hua, Huang, Ruili, Lin, Ja-An, Sedykh, Alexander, Zhao, Jinghua, Tice, Raymond R, Paules, Richard S, Xia, Menghang, Auerbach, Scott S

“…Cytotoxicity is a commonly used in vitro endpoint for evaluating chemical toxicity. In support of the U.S. Tox21 screening program, the cytotoxicity of ~10K…”
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Alternatively spliced isoforms of the human constitutive androstane receptor by Auerbach, Scott S., Ramsden, Richard, Stoner, Matthew A., Verlinde, Christophe, Hassett, Christopher, Omiecinski, Curtis J.

“…The nuclear receptor CAR (NR1I3) regulates transcription of genes encoding xenobiotic‐ and steroid‐metabolizing enzymes. Regulatory processes that are mediated…”
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