Search Results - "AUDIT, B"
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Revealing long-range interconnected hubs in human chromatin interaction data using graph theory
Published in Physical review letters (10-09-2013)“…We use graph theory to analyze chromatin interaction (Hi-C) data in the human genome. We show that a key functional feature of the genome--"master" replication…”
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2
SWDreader: A wavelet-based algorithm using spectral phase to characterize spike-wave morphological variation in genetic models of absence epilepsy
Published in Journal of neuroscience methods (15-03-2015)“…•Standard terms of EEG/ECoG morphology are ill-suited to analyzing seizure variants.•Categorical descriptions are used because morphology eludes numerical…”
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3
Experiments confirm the influence of genome long-range correlations on nucleosome positioning
Published in Physical review letters (23-11-2007)“…From the statistical analysis of nucleosome positioning data for chromosome III of S. cerevisiae, we demonstrate that long-range correlations (LRC) in the…”
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4
Deciphering DNA replication dynamics in eukaryotic cell populations in relation with their averaged chromatin conformations
Published in Scientific reports (03-03-2016)“…We propose a non-local model of DNA replication that takes into account the observed uncertainty on the position and time of replication initiation in…”
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5
Inferring where and when replication initiates from genome-wide replication timing data
Published in Physical review letters (29-06-2012)“…Based on an analogy between DNA replication and one dimensional nucleation-and-growth processes, various attempts to infer the local initiation rate I(x,t) of…”
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6
Replication-Associated Strand Asymmetries in Mammalian Genomes: Toward Detection of Replication Origins
Published in Proceedings of the National Academy of Sciences - PNAS (12-07-2005)“…In the course of evolution, mutations do not affect both strands of genomic DNA equally. This imbalance mainly results from asymmetric DNA mutation and repair…”
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7
Linking the DNA strand asymmetry to the spatio-temporal replication program: II. Accounting for neighbor-dependent substitution rates
Published in The European physical journal. E, Soft matter and biological physics (01-11-2012)“…In paper I, we addressed the impact of the spatio-temporal program on the DNA composition evolution in the case of time homogeneous and neighbor-independent…”
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Linking the DNA strand asymmetry to the spatio-temporal replication program: I. About the role of the replication fork polarity in genome evolution
Published in The European physical journal. E, Soft matter and biological physics (01-09-2012)“…Two key cellular processes, namely transcription and replication, require the opening of the DNA double helix and act differently on the two DNA strands,…”
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9
Revisiting polymer statistical physics to account for the presence of long-range-correlated structural disorder in 2D DNA chains
Published in The European physical journal. E, Soft matter and biological physics (01-11-2011)“…We elaborate on a generalization of the 2D wormlike chain (WLC) model that accounts for the presence of long-range correlations (LRC) in the intrinsic…”
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10
Long-range correlations in genomic DNA: a signature of the nucleosomal structure
Published in Physical review letters (12-03-2001)“…We use the "wavelet transform microscope" to carry out a comparative statistical analysis of DNA bending profiles and of the corresponding DNA texts. In the…”
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11
Revealing intermittency in experimental data with steep power spectra
Published in Europhysics letters (01-06-2010)“…The statistics of signal increments are commonly used in order to test for possible intermittent properties in experimental or synthetic data. However, for…”
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12
Generalized wormlike chain model for long-range correlated heteropolymers
Published in Europhysics letters (01-05-2009)“…We extend the 2D wormlike chain model (WLC) for semiflexible polymers to long-range correlated (LRC) heteropolymers. The conjugated contributions of i) the…”
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13
Thermodynamics of DNA loops with long-range correlated structural disorder
Published in Physical review letters (05-08-2005)“…We study the influence of a structural disorder on the thermodynamical properties of 2D-elastic chains submitted to mechanical/topological constraint as loops…”
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14
Wavelet-based estimators of scaling behavior
Published in IEEE transactions on information theory (01-11-2002)“…Various wavelet-based estimators of self-similarity or long-range dependence scaling exponent are studied extensively. These estimators mainly include the…”
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15
DNA replication timing data corroborate in silico human replication origin predictions
Published in Physical review letters (14-12-2007)“…We develop a wavelet-based multiscale pattern recognition methodology to disentangle the replication- from the transcription-associated compositional strand…”
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16
Spontaneous emergence of sequence-dependent rosettelike folding of chromatin fiber
Published in Physical Review Special Topics: Physics Education Research (01-06-2008)“…In the crowded environment of the eukaryotic nucleus, the presence of intrinsic structural defects is shown to predispose chromatin fiber to spontaneously form…”
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17
From DNA sequence analysis to modeling replication in the human genome
Published in Physical review letters (24-06-2005)“…We explore the large-scale behavior of nucleotide compositional strand asymmetries along human chromosomes. As we observe for 7 of 9 origins of replication…”
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18
Formation and positioning of nucleosomes: effect of sequence-dependent long-range correlated structural disorder
Published in The European physical journal. E, Soft matter and biological physics (01-03-2006)“…The understanding of the long-range correlations (LRC) observed in DNA sequences is still an open and very challenging problem. In this paper, we start…”
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19
Strain-specific genes of Helicobacter pylori: distribution, function and dynamics
Published in Nucleic acids research (01-11-2001)“…Whole-genome clustering of the two available genome sequences of Helicobacter pylori strains 26695 and J99 allows the detection of 110 and 52 strain-specific…”
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20
CoGenT++: an extensive and extensible data environment for computational genomics
Published in Bioinformatics (01-10-2005)“…Motivation: CoGenT++ is a data environment for computational research in comparative and functional genomics, designed to address issues of consistency,…”
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