Search Results - "AUBIN, Chantal St"

Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility by NAGENDRAN, Jayan, ARCHER, Stephen L, LIGHT, Peter E, DYCK, Jason R. B, MICHELAKIS, Evangelos D, SOLIMAN, Daniel, GURTU, Vikram, MOUDGIL, Rohit, HAROMY, Alois, AUBIN, Chantal St, WEBSTER, Linda, REBEYKA, Ivan M, ROSS, David B

“…Sildenafil was recently approved for the treatment of pulmonary arterial hypertension. The beneficial effects of phosphodiesterase type 5 (PDE5) inhibitors in…”
Get full text

Positive charges at the intracellular mouth of the pore regulate anion conduction in the CFTR chloride channel by Aubin, Chantal N St, Linsdell, Paul

“…Many different ion channel pores are thought to have charged amino acid residues clustered around their entrances. The so-called surface charges contributed by…”
Get full text

Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore by St Aubin, Chantal N, Zhou, Jing-Jun, Linsdell, Paul

“…Chloride transport by the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel is inhibited by a broad range of substances that bind within…”
Get more information

On the Origin of Asymmetric Interactions between Permeant Anions and the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore by Fatehi, Mohammad, St. Aubin, Chantal N., Linsdell, Paul

“…Single channel and macroscopic current recording was used to investigate block of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl − channel…”
Get full text