Search Results - "AUBIER, MICHEL"

Effectiveness of bronchial thermoplasty in patients with severe refractory asthma: Clinical and histopathologic correlations by Pretolani, Marina, PharmD, PhD, Bergqvist, Anders, PhD, Thabut, Gabriel, MD, PhD, Dombret, Marie-Christine, MD, Knapp, Dominique, MS, Hamidi, Fatima, MS, Alavoine, Loubna, MD, Taillé, Camille, MD, PhD, Chanez, Pascal, MD, PhD, Erjefält, Jonas S., PhD, Aubier, Michel, MD

“…Background The effectiveness of bronchial thermoplasty (BT) has been reported in patients with severe asthma, yet its effect on different bronchial structures…”
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IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration by Dagher, Rania, Copenhaver, Alan M., Besnard, Valerie, Berlin, Aaron, Hamidi, Fatima, Maret, Marielle, Wang, Jingya, Qu, Xiaotao, Shrestha, Yashaswi, Wu, Jincheng, Gautier, Gregory, Raja, Rajiv, Aubier, Michel, Kolbeck, Roland, Humbles, Alison A., Pretolani, Marina

“…Evidence points to an indispensable function of macrophages in tissue regeneration, yet the underlying molecular mechanisms remain elusive. Here we demonstrate…”
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Circulating innate lymphoid cells are differentially regulated in allergic and nonallergic subjects by Lombardi, Vincent, PhD, Beuraud, Chloé, MSc, Neukirch, Catherine, MD, Moussu, Hélène, MSc, Morizur, Lise, MSc, Horiot, Stéphane, BSc, Luce, Sonia, MSc, Wambre, Erik, PhD, Linsley, Peter, PhD, Chollet-Martin, Sylvie, PhD, Baron-Bodo, Véronique, PhD, Aubier, Michel, MD, PhD, Moingeon, Philippe, PhD

“…To the Editor: A new family of lymphocyte-like cells, termed innate lymphoid cells (ILCs), lacking a specific antigen receptor, belonging to the innate immune…”
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Obstructive Sleep Apnoea Modulates Airway Inflammation and Remodelling in Severe Asthma by Taillé, Camille, Rouvel-Tallec, Anny, Stoica, Maria, Danel, Claire, Dehoux, Monique, Marin-Esteban, Viviana, Pretolani, Marina, Aubier, Michel, d'Ortho, Marie-Pia

“…Obstructive sleep apnoea (OSA) is frequently observed in severe asthma but the causal link between the 2 diseases remains hypothetical. The role of OSA-related…”
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Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End Products in Chronic Obstructive Pulmonary Disease by FERHANI, Nassima, LETUVE, Séverine, AUBIER, Michel, PRETOLANI, Marina, KOZHICH, Alexander, THIBAUDEAU, Olivier, GRANDSAIGNE, Martine, MARET, Marielle, DOMBRET, Marie-Christine, SIMS, Gary P, KOLBECK, Roland, COYLE, Anthony J

“…Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation and remodeling. High-mobility group box 1 (HMGB1), a nuclear protein that…”
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[ 18 F]FDG PET/CT predicts progression-free survival in patients with idiopathic pulmonary fibrosis by Justet, Aurélien, Laurent-Bellue, Astrid, Thabut, Gabriel, Dieudonné, Arnaud, Debray, Marie-Pierre, Borie, Raphael, Aubier, Michel, Lebtahi, Rachida, Crestani, Bruno

“…Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by an unpredictable course. Prognostic markers and disease activity markers are…”
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Clinical and biological characteristics of the French COBRA cohort of adult subjects with asthma by Pretolani, Marina, Soussan, David, Poirier, Isabelle, Thabut, Gabriel, Aubier, Michel

“…The COhort of BRonchial obstruction and Asthma (COBRA) is a longitudinal cohort that involves 12 French academic institutions. DNA, serum samples and clinical…”
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Repeated nitrogen dioxide exposures and eosinophilic airway inflammation in asthmatics: a randomized crossover study by Ezratty, Véronique, Guillossou, Gaëlle, Neukirch, Catherine, Dehoux, Monique, Koscielny, Serge, Bonay, Marcel, Cabanes, Pierre-André, Samet, Jonathan M, Mure, Patrick, Ropert, Luc, Tokarek, Sandra, Lambrozo, Jacques, Aubier, Michel

“…Nitrogen dioxide (NO2), a ubiquitous atmospheric pollutant, may enhance the asthmatic response to allergens through eosinophilic activation in the airways…”
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Early computed tomography modifications following bronchial thermoplasty in patients with severe asthma by Debray, Marie-Pierre, Dombret, Marie-Christine, Pretolani, Marina, Thabut, Gabriel, Alavoine, Loubna, Brillet, Pierre-Yves, Taillé, Camille, Khalil, Antoine, Chanez, Pascal, Aubier, Michel

“…Bronchial thermoplasty (BT) is a recent, promising and well-tolerated technique for the treatment of severe asthma. By delivering thermal energy to the airway…”
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Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD by Rania Dagher, Paul Fogel, Jingya Wang, David Soussan, Chia-Chien Chiang, Jennifer Kearley, Daniel Muthas, Camille Taillé, Patrick Berger, Arnaud Bourdin, Cécile Chenivesse, Sylvie Leroy, Gary Anderson, Alison A Humbles, Michel Aubier, Roland Kolbeck, Marina Pretolani, COBRA Consortium

“…ObjectiveNovel biomarkers related to main clinical hallmarks of Chronic obstructive pulmonary disease (COPD), a heterogeneous disorder with pulmonary and…”
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Airway smooth muscle enlargement is associated with protease-activated receptor 2/ligand overexpression in patients with difficult-to-control severe asthma by Aubier, Michel, MD, Thabut, Gabriel, MD, PhD, Hamidi, Fatima, MSc, Guillou, Noëlline, MSc, Brard, Julien, MSc, Dombret, Marie-Christine, MD, Borensztajn, Keren, PhD, Aitilalne, Brahim, MSc, Poirier, Isabelle, BNBP, Roland-Nicaise, Pascale, PharmD, PhD, Taillé, Camille, MD, PhD, Pretolani, Marina, PharmD, PhD

“…Background Asthma is a complex disease with heterogeneous features of airway inflammation and remodeling. The increase in airway smooth muscle (ASM) mass is an…”
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Bronchial thermoplasty: a new therapeutic option for the treatment of severe, uncontrolled asthma in adults by Dombret, Marie-Christine, Alagha, Khuder, Boulet, Louis Philippe, Brillet, Pierre Yves, Joos, Guy, Laviolette, Michel, Louis, Renaud, Rochat, Thierry, Soccal, Paola, Aubier, Michel, Chanez, Pascal

“…Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit for long-term asthma control outweighs the short-term risk of…”
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Association between asthma and rhinitis according to atopic sensitization in a population-based study by Leynaert, Bénédicte, Neukirch, Catherine, Kony, Sabine, Guénégou, Armelle, Bousquet, Jean, Aubier, Michel, Neukirch, Françoise

“…Although asthma and rhinitis often occur together, the reason for this common comorbidity is still a matter of debate. We sought to assess whether the…”
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Radiological abnormalities following bronchial thermoplasty: is the pathophysiology understood? by Debray, Marie-Pierre, Dombret, Marie-Christine, Pretolani, Marina, Thabut, Gabriel, Alavoine, Loubna, Brillet, Pierre-Yves, Taillé, Camille, Khalil, Antoine, Chanez, Pascal, Aubier, Michel

“…We read with great interest the correspondence by J.N.S. d'Hooghe and colleagues focusing on the pathophysiology of early transient radiological abnormalities…”
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Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats by Lanone, Sophie, Bloc, Sébastien, Foresti, Roberta, Almolki, Abdelhamid, Taillé, Camille, Callebert, Jacques, Conti, Marc, Goven, Delphine, Aubier, Michel, Dureuil, Bertrand, El-Benna, Jamel, Motterlini, Roberto, Boczkowski, Jorge

“…ABSTRACTWe investigated a possible beneficial role for bilirubin, one of the products of heme degradation by the cytoprotective enzyme heme oxygenase‐1 in…”
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Lung Chitinolytic Activity and Chitotriosidase Are Elevated in Chronic Obstructive Pulmonary Disease and Contribute to Lung Inflammation by Létuvé, Séverine, Kozhich, Alexander, Humbles, Alison, Brewah, Yambasu, Dombret, Marie-Christine, Grandsaigne, Martine, Adle, Homa, Kolbeck, Roland, Aubier, Michel, Coyle, Anthony J, Pretolani, Marina

“…Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation and emphysematous alveolar destruction. In this study, we have…”
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ANCA-associated lung fibrosis: Analysis of 17 patients by Foulon, Guillaume, Delaval, Philippe, Valeyre, Dominique, Wallaert, Benoît, Debray, Marie-Pierre, Brauner, Michel, Nicaise, Pascale, Cadranel, Jacques, Cottin, Vincent, Tazi, Abdellatif, Aubier, Michel, Crestani, Bruno

“…Summary In this retrospective study, we analyzed 17 patients presenting with pulmonary fibrosis and a positive ANCA testing. This group was compared with a…”
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Biological Effects of Particles from the Paris Subway System by Bachoual, Rafik, Boczkowski, Jorge, Goven, Delphine, Amara, Nadia, Tabet, Lyes, On, Dinhill, Leçon-Malas, Véronique, Aubier, Michel, Lanone, Sophie

“…Particulate matter (PM) from atmospheric pollution can easily deposit in the lungs and induce recruitment of inflammatory cells, a source of inflammatory…”
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Neural substrates for the perception of acutely induced dyspnea by PEIFFER, Claudine, POLINE, Jean-Baptiste, THIVARD, Lionel, AUBIER, Michel, SAMSON, Yves

“…Little is currently known about the brain regions involved in central processing of dyspnea. We performed a functional imaging study with positron emission…”
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Circulating neutrophil and eosinophil extracellular traps are markers of severe asthma by Granger, Vanessa, Taillé, Camille, Roach, Dwayne, Letuvé, Séverine, Dupin, Clairelyne, Hamidi, Fatima, Noël, Benoît, Neukirch, Catherine, Aubier, Michel, Pretolani, Marina, Chollet-Martin, Sylvie, De Chaisemartin, Luc

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