Search Results - "ATWOOD, Walter J"

The biology of JC polyomavirus by Assetta, Benedetta, Atwood, Walter J

“…JC polyomavirus (JCPyV) is the causative agent of a fatal central nervous system demyelinating disease known as progressive multifocal leukoencephalopathy…”
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Complexities of JC Polyomavirus Receptor-Dependent and -Independent Mechanisms of Infection by Morris-Love, Jenna, Atwood, Walter J

“…JC polyomavirus (JCPyV) is a small non-enveloped virus that establishes lifelong, persistent infection in most of the adult population. Immune-competent…”
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Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain by FERENCZY, Michael W, MARSHALL, Leslie J, NELSON, Christian D. S, ATWOOD, Walter J, NATH, Avindra, KHALILI, Kamel, MAJOR, Eugene O

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Fifty Years of JC Polyomavirus: A Brief Overview and Remaining Questions by Atkinson, Abigail L, Atwood, Walter J

“…In the fifty years since the discovery of JC polyomavirus (JCPyV), the body of research representing our collective knowledge on this virus has grown…”
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JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor by O'Hara, Bethany A, Morris-Love, Jenna, Gee, Gretchen V, Haley, Sheila A, Atwood, Walter J

“…The human polyomavirus, JCPyV, is the causative agent of progressive multifocal leukoencephalopathy (PML) in immunosuppressed and immunomodulated patients…”
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JC Polyomavirus Uses Extracellular Vesicles To Infect Target Cells by Morris-Love, Jenna, Gee, Gretchen V, O'Hara, Bethany A, Assetta, Benedetta, Atkinson, Abigail L, Dugan, Aisling S, Haley, Sheila A, Atwood, Walter J

“…The endemic human JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy in immune-suppressed patients. The mechanisms of virus infection…”
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Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus by Lipovsky, Alex, Popa, Andreea, Pimienta, Genaro, Wyler, Michael, Bhan, Ashima, Kuruvilla, Leena, Guie, Marie-Aude, Poffenberger, Adrian C., Nelson, Christian D. S., Atwood, Walter J., DiMaio, Daniel

“…Despite major advances in our understanding of many aspects of human papillomavirus (HPV) biology, HPV entry is poorly understood. To identify cellular genes…”
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An Elusive Target: Inhibitors of JC Polyomavirus Infection and Their Development as Therapeutics for the Treatment of Progressive Multifocal Leukoencephalopathy by Kaiserman, Jacob, O'Hara, Bethany A, Haley, Sheila A, Atwood, Walter J

“…Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease caused by infection with JC Polyomavirus (JCPyV). Despite the identification…”
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Highly restrictive and directional penetration of the blood cerebral spinal fluid barrier by JCPyV by O'Hara, Bethany A, Lukacher, Avraham S, Garabian, Kaitlin, Kaiserman, Jacob, MacLure, Evan, Ishikawa, Hiroshi, Schroten, Horst, Haley, Sheila A, Atwood, Walter J

“…The human polyomavirus JCPyV is an opportunistic pathogen that infects greater than 60% of the world's population. The virus establishes a persistent and…”
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JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response by Assetta, Benedetta, De Cecco, Marco, O'Hara, Bethany, Atwood, Walter J

“…The JC and BK human polyomaviruses (JCPyV and BKPyV, respectively) establish lifelong persistent infections in the kidney. In immunosuppressed individuals,…”
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Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif by Neu, Ursula, Maginnis, Melissa S, Palma, Angelina S, Ströh, Luisa J, Nelson, Christian D S, Feizi, Ten, Atwood, Walter J, Stehle, Thilo

“…The human JC polyomavirus (JCV) causes a fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML), in immunocompromised individuals…”
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A structure-guided mutation in the major capsid protein retargets BK polyomavirus by Neu, Ursula, Allen, Stacy-Ann A, Blaum, Bärbel S, Liu, Yan, Frank, Martin, Palma, Angelina S, Ströh, Luisa J, Feizi, Ten, Peters, Thomas, Atwood, Walter J, Stehle, Thilo

“…Viruses within a family often vary in their cellular tropism and pathogenicity. In many cases, these variations are due to viruses switching their specificity…”
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The Oxindole GW-5074 Inhibits JC Polyomavirus Infection and Spread by Antagonizing the MAPK-ERK Signaling Pathway by Kaiserman, Jacob, O'Hara, Bethany A, Garabian, Kaitlin, Lukacher, Avraham, Haley, Sheila A, Atwood, Walter J

“…JC polyomavirus (JCPyV) is a ubiquitous, double-stranded DNA virus that causes the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML)…”
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JCPyV infection of primary choroid plexus epithelial cells reduces expression of critical junctional proteins and increases expression of barrier disrupting inflammatory cytokines by Haley, Sheila A, O'Hara, Bethany A, Schorl, Christoph, Atwood, Walter J

“…The human polyomavirus, JCPyV, establishes a lifelong persistent infection in the peripheral organs of a majority of the human population worldwide. Patients…”
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Decreased function of survival motor neuron protein impairs endocytic pathways by Dimitriadi, Maria, Derdowski, Aaron, Kalloo, Geetika, Maginnis, Melissa S., O’Hern, Patrick, Bliska, Bryn, Sorkaç, Altar, Nguyen, Ken C. Q., Cook, Steven J., Poulogiannis, George, Atwood, Walter J., Hall, David H., Hart, Anne C.

“…Spinal muscular atrophy (SMA) is caused by depletion of the ubiquitously expressed survival motor neuron (SMN) protein, with 1 in 40 Caucasians being…”
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5-HT2 Receptors Facilitate JC Polyomavirus Entry by Assetta, Benedetta, Maginnis, Melissa S, Gracia Ahufinger, Irene, Haley, Sheila A, Gee, Gretchen V, Nelson, Christian D S, O'Hara, Bethany A, Allen Ramdial, Stacy-ann A, Atwood, Walter J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity by Ströh, Luisa J, Maginnis, Melissa S, Blaum, Bärbel S, Nelson, Christian D S, Neu, Ursula, Gee, Gretchen V, O'Hara, Bethany A, Motamedi, Nasim, DiMaio, Daniel, Atwood, Walter J, Stehle, Thilo

“…The human JC polyomavirus (JCPyV) establishes an asymptomatic, persistent infection in the kidneys of the majority of the population and is the causative agent…”
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MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection by Zhou, Lanlan, Huntington, Kelsey, Zhang, Shengliang, Carlsen, Lindsey, So, Eui-Young, Parker, Cassandra, Sahin, Ilyas, Safran, Howard, Kamle, Suchitra, Lee, Chang-Min, Geun Lee, Chun, A Elias, Jack, S Campbell, Kerry, T Naik, Mandar, J Atwood, Walter, Youssef, Emile, A Pachter, Jonathan, Navaraj, Arunasalam, A Seyhan, Attila, Liang, Olin, El-Deiry, Wafik S

“…COVID-19 affects vulnerable populations including elderly individuals and patients with cancer. Natural Killer (NK) cells and innate-immune TRAIL suppress…”
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Progressive Multifocal Leukoencephalopathy: Endemic Viruses and Lethal Brain Disease by Haley, Sheila A, Atwood, Walter J

“…In 1971, the first human polyomavirus was isolated from the brain of a patient who died from a rapidly progressing demyelinating disease known as progressive…”
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Correction for Assetta et al., "JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response" by Assetta, Benedetta, De Cecco, Marco, O'Hara, Bethany, Atwood, Walter J

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