Search Results - "ATHAR ABBASI, MUHAMMAD"

Design, Synthesis, Biological Evaluation and Molecular Docking Studies of Some New Sulfonamides Possessing 1,4-Benzodioxane Nucleus by Irshad, Misbah, Abbasi, Muhammad Athar, Rehman, Aziz Ur, Ali, Qamar, Iram, Fozia, Shahid, Muhammad, Ashraf, Muhammad, Lodhi, Muhammad Arif, Jamal, Syed Babar

“…In the current research work we have reported a series of N-aryl-2,3-dihydrobenzo[1,4]dioxine-6-sulfonamides 3 and their N-substituted derivatives 6 and 7,…”
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Synthesis of Some Unique Carbamate Derivatives bearing 2-Furoyl-1-piperazine as a Valuable Therapeutic Agents by Abbasi, Muhammad, Athar, Hussain, Ghulam, Rehman, Aziz Ur, Siddiqui, Sabahat, Zahra, Shah, Syed, Adnan Ali, Lodhi, Muhammad, Arif, Khan, Farman, Ali, Ashraf, Muhammad, Ain, Qurat Ul, Ahmad, Irshad, Malik, Rabia, Shahid, Muhammad, Mushtaq, Zahid

“…The aim of the research work was to synthesize different biologically active carbamate derivatives bearing 2-furoyl-1-piperazine and having modest toxicity…”
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Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells by Athar Abbasi, Muhammad, Yu, Seon-Mi, Aziz-ur-Rehman, Siddiqui, Sabahat Zahra, Kim, Song Ja, Raza, Hussain, Hassan, Mubashir, Rehman Sadiq Butt, Abdul, Shah, Syed Adnan Ali, Seo, Sung-Yum

“…[Display omitted] In the study presented here, a novel chlorobenzylated bi-heterocyclic hybrid molecule (7) was synthesized and its structural confirmation was…”
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The exploration of novel Alzheimer’s therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approaches by Hassan, Mubashir, Raza, Hussain, Abbasi, Muhammad Athar, Moustafa, Ahmed A., Seo, Sung-Yum

“…[Display omitted] •Drug repositioning approach was used to predict the possible therapeutic effects of FDA approved drugs against AD disease.•The screened…”
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Three New Cholinesterase-Inhibiting cis-Clerodane Diterpenoids from Otostegia limbata by Ahmad, Viqar Uddin, Khan, Afsar, Farooq, Umar, Kousar, Farzana, Khan, Saleha Suleman, Nawaz, Sarfraz Ahmad, Abbasi, Muhammad Athar, Choudhary, Muhammad Iqbal

“…Three new tricyclic cis-clerodane type diterpenoids trivially named as limbatolide A (1), limbatolide B (2) and limbatolide C (3) have been isolated from the…”
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Synthesis of novel N-(1,3-thiazol-2-yl)benzamide clubbed oxadiazole scaffolds: Urease inhibition, Lipinski rule and molecular docking analyses by Athar Abbasi, Muhammad, Raza, Hussain, Aziz-ur-Rehman, Zahra Siddiqui, Sabahat, Adnan Ali Shah, Syed, Hassan, Mubashir, Seo, Sung-Yum

“…[Display omitted] •Synthesis of bi-heterocyclic scaffolds.•Structural characterization with spectral analysis.•Urease inhibition and structure-activity…”
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2‐Aminothiazole‐Oxadiazole Bearing N‐Arylated Butanamides: Convergent Synthesis, Tyrosinase Inhibition, Kinetics, Structure‐Activity Relationship, and Binding Conformations by Raza, Hussain, Rehman Sadiq Butt, Abdul, Athar Abbasi, Muhammad, Aziz‐ur‐Rehman, Zahra Siddiqui, Sabahat, Hassan, Mubashir, Adnan Ali Shah, Syed, Ja Kim, Song

“…A multi‐step synthesis of novel bi‐heterocyclic N‐arylated butanamides was consummated through a convergent strategy and the structures of these medicinal…”
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Synthesis of Bi-heterocyclic Sulfonamides as Tyrosinase Inhibitors: Lineweaver-Burk Plot Evaluation and Computational Ascriptions by Abbasi, Muhammad Athar, Rehman, Zia-Ur, Rehman, Aziz-Ur, Siddiqui, Sabahat Zahra, Nazir, Majid, Hassan, Mubashir, Raza, Hussain, Shah, Syed Adnan Ali, Seo, Sung-Yum

“…The designed bi-heterocyclic sulfonamides were synthesized through a two-step protocol and their structures were ascertained by spectral techniques including…”
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Synthesis of Novel Bi-Heterocycles as Valuable Anti-Diabetic Agents: 2-({5-((2-Amino-1,3-Thiazol-4-yl)methyl)-1,3,4-Oxadiazol-2-yl}sulfanyl)-N-(Substituted)acetamides by Muhammad Athar Abbasi, Ramzan, Muhammad Shahid, Aziz-ur-Rehman, Siddiqui, Sabahat Zahra, Shah, Syed Adnan Ali, Lodhi, Muhammad Arif, Khan, Farman Ali, Mirza, Bushra

“…The synthesis of a new series of S -substituted acetamides derivatives of 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazol-2-thiol were synthesized and…”
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Synthesis of new N-(5-chloro-2-methoxyphenyl)-4-(5-substituted-1,3,4-oxadiazol-2-ylthio)butanamide derivatives as suitable lipoxygenase inhibitors by Aziz-ur-Rehman, Fatima, Ambreen, Abbasi, Muhammad Athar, Rasool, Shahid, Malik, Abdul, Ashraf, Muhammad, Ahmad, Irshad, Ejaz, Syeda Abida

“…Heterocyclic compounds are the most attractive class for researchers due to their biological activities. In the undertaken research, a number of…”
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Four New Diterpenoids from Ballota limbata by Ahmad, Viqar Uddin, Farooq, Umar, Abbaskhan, Ahmed, Hussain, Javid, Abbasi, Muhammad Athar, Nawaz, Sarfraz Ahmad, Choudhary, M. Iqbal

“…Six diterpenoids (1–6) belonging to the clerodane and tetracyclic diterpene types were isolated from the CHCl3 extract of Ballota limbata. The structures of…”
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Synthesis, enzyme inhibitory kinetics mechanism and computational study of N -(4-methoxyphenethyl)- N -(substituted)-4-methylbenzenesulfonamides as novel therapeutic agents for Alzheimer's disease by Abbasi, Muhammad Athar, Hassan, Mubashir, Aziz-Ur-Rehman, Siddiqui, Sabahat Zahra, Shah, Syed Adnan Ali, Raza, Hussain, Seo, Sung Yum

“…The present study comprises the synthesis of a new series of sulfonamides derived from 4-methoxyphenethylamine ( ). The synthesis was initiated by the reaction…”
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Structure-activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives by Abbasi, Muhammad, Ramzan, Muhammad, Aziz-Ur-Rehman, A, Siddiqui, Sabahat, Hassan, Mubashir, Raza, Hussain, Shah, Syed, Mirza, Bushra, Seo, Sung-Yum

“…This paper presents the synthesis of some unique bi-heterocyclic hybrid molecules with a thiazole and an oxadiazole ring. The synthesis was initiated by the…”
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Synthesis, biological evaluation, and in silico study of some unique multifunctional 1,2,4-triazole acetamides by SATTAR, ALMAS, REHMAN, AZIZ UR, ATHAR ABBASI, MUHAMMAD, SADDIQUI, SABAHAT ZAHRA, RASOOL, SHAHID, KHALID, HIRA, LODHI, MUHAMMAD ARIF, KHAN, FARMAN ALI

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Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol by Shehzadi, Naureen, Hussain, Khalid, Islam, Muhammad, Bukhari, Nadeem Irfan, Khan, Muhammad Tanveer, Salman, Muhammad, Siddiqui, Sabahat Zahra, Rehman, Aziz-Ur, Abbasi, Muhammad Athar

“…The study describes the development and preliminary validation of a simple reverse-phase chromatographic method for determination of a novel drug candidate,…”
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Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and BSA binding studies by Iqbal, Javed, Rehman, Aziz-ur, Abbasi, Muhammad Athar, Siddiqui, Sabahat Zahra, Rasool, Shahid, Ashraf, Muhammad, Iqbal, Ambar, Hamid, Sujhla, Chohan, Tahir Ali, Khalid, Hira, Laulloo, Sabina Jhaumeer, Shah, Syed Adnan Ali

“…We synthesized a series of compounds bearing pharmacologically important 1,3,4-oxadiazole and piperidine moieties. Spectral data analysis by 1H-NMR, 13C-NMR,…”
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Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4-methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl)acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study by Abbasi, Muhammad Athar, Riaz, Sajid, Rehman, Aziz-ur, Siddiqui, Sabahat Zahra, Shah, Syed Adnan Ali, Ashraf, Muhammad, Lodhi, Muhammad Arif, Khan, Farman Ali

“…The aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties…”
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Hypoglycemic, hepatoprotective and molecular docking studies of 5-[(4-chlorophenoxy) methyl]-1, 3, 4-oxadiazole-2-thiol by Naureen Shehzadi, Khalid Hussain, Nadeem Irfan Bukhari, Muhammad Islam, Muhammad Tanveer Khan, Muhammad Salman, Sabahat Zahra Siddiqui, Aziz Ur Rehman, Muhammad Athar Abbasi

“…The present study aimed at the evaluation of anti-hyperglycemic and hepatoprotective potential of a new drug candidate, 5-[(4-chlorophenoxy)…”
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Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides by Rasool, Shahid, Aziz-ur-Rehman, Abbasi, Muhammad Athar, Siddiqui, Sabahat Z, Shah, Syed Adnan Ali

“…A series of molecules bearing multiple functional groups were synthesized to study their antibiotic effect against Gram-positive and Gram-negative bacteria and…”
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Synthesis of some novel enzyme inhibitors and antibacterial agents derived from 5-(1-(4-tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol by Sattar, Almas, Aziz-ur-Rehman, Abbasi, Muhammad Athar, Siddiqui, Sabahat Zahra, Rasool, Shahid, Ahmad, Irshad

“…ABSTRACT Keeping in mind the pharmacological importance of the 1,3,4-oxadiazole moiety, a series of new S-substituted derivatives, 5a-h, of…”
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