Search Results - "ASMUS, Friedrich"

Intravitreal antisense oligonucleotide sepofarsen in Leber congenital amaurosis type 10: a phase 1b/2 trial by Russell, Stephen R., Drack, Arlene V., Cideciyan, Artur V., Jacobson, Samuel G., Leroy, Bart P., Van Cauwenbergh, Caroline, Ho, Allen C., Dumitrescu, Alina V., Han, Ian C., Martin, Mitchell, Pfeifer, Wanda L., Sohn, Elliott H., Walshire, Jean, Garafalo, Alexandra V., Krishnan, Arun K., Powers, Christian A., Sumaroka, Alexander, Roman, Alejandro J., Vanhonsebrouck, Eva, Jones, Eltanara, Nerinckx, Fanny, De Zaeytijd, Julie, Collin, Rob W. J., Hoyng, Carel, Adamson, Peter, Cheetham, Michael E., Schwartz, Michael R., den Hollander, Wilhelmina, Asmus, Friedrich, Platenburg, Gerard, Rodman, David, Girach, Aniz

“…CEP290-associated Leber congenital amaurosis type 10 (LCA10) is a retinal disease resulting in childhood blindness. Sepofarsen is an RNA antisense…”
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Refractory post-surgical cystoid macular edema managed following suprachoroidal microcatheterization and delivery of triamcinolone by de Smet, Marc D, Goncerut, Matthieu, Asmus, Friedrich, Yamamoto, Ron

“…Background Post-surgical macular edema (ME) is a common cause of prolonged visual impairment. Here we report on the feasibility and clinical outcomes from the…”
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Pallidal and thalamic deep brain stimulation in myoclonus-dystonia by Gruber, Doreen, Kühn, Andrea A., Schoenecker, Thomas, Kivi, Anatol, Trottenberg, Thomas, Hoffmann, Karl-Titus, Gharabaghi, Alireza, Kopp, Ute A., Schneider, Gerd-Helge, Klein, Christine, Asmus, Friedrich, Kupsch, Andreas

“…Deep brain stimulation (DBS) of the internal globus pallidus (GPi) and ventral intermediate thalamic nucleus (VIM) are established treatment options in primary…”
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Sustained dopaminergic response of parkinsonism and depression in POLG-associated parkinsonism by Synofzik, Matthis, Asmus, Friedrich, Reimold, Matthias, Schöls, Ludger, Berg, Daniela

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Integrated results from the COPERNICUS and GALILEO studies by Pielen, Amelie, Clark, W Lloyd, Boyer, David S, Ogura, Yuichiro, Holz, Frank G, Korobelnik, Jean-Francois, Stemper, Brigitte, Asmus, Friedrich, Rittenhouse, Kay D, Ahlers, Christiane, Vitti, Robert, Saroj, Namrata, Zeitz, Oliver, Haller, Julia A

“…To report on the efficacy and safety of intravitreal aflibercept in patients with macular edema secondary to central retinal vein occlusion (CRVO) in an…”
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Clinical differentiation of genetically proven benign hereditary chorea and myoclonus-dystonia by Asmus, Friedrich, Devlin, Anita, Munz, Marita, Zimprich, Alexander, Gasser, Thomas, Chinnery, Patrick F.

“…Because of clinical similarities, benign hereditary chorea and myoclonus‐dystonia (DYT11) might be confused. No systematic comparisons of genetically proven…”
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Intravitreal Aflibercept Injection in Patients with Myopic Choroidal Neovascularization by Ikuno, Yasushi, MD, Ohno-Matsui, Kyoko, MD, Wong, Tien Yin, MD, PhD, Korobelnik, Jean-Francois, MD, Vitti, Robert, MD, Li, Tummy, MPH, Stemper, Brigitte, MD, Asmus, Friedrich, MD, Zeitz, Oliver, MD, Ishibashi, Tatsuro, MD, PhD

“…Purpose To evaluate intravitreal aflibercept 2 mg in patients with myopic choroidal neovascularization (CNV). Design An international, phase III, multicenter,…”
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The epsilon-sarcoglycan gene ( ), mutated in myoclonus-dystonia syndrome, is maternally imprinted by GRABOWSKI, Monika, ZIMPRICH, Alexander, LORENZ-DEPIEREUX, Bettina, KALSCHEUER, Vera, ASMUS, Friedrich, GASSER, Thomas, MEITINGER, Thomas, STROM, Tim M

“…Myoclonus-dystonia syndrome (MDS) is a non-degenerative neurological disorder that has been described to be inherited in an autosomal dominant mode with…”
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Reverse sensory geste in cervical dystonia by Asmus, Friedrich, von Coelln, Rainer, Boertlein, Axel, Gasser, Thomas, Mueller, Joerg

“…Sensory gestes (SG) are a pathognomonic sign of dystonia, which can be detected in up to two thirds of patients with cervical dystonia (CD). They reduce…”
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Intrafamilial variability in fragile X-associated tremor/ataxia syndrome by Peters, Nils, Kamm, Christoph, Asmus, Friedrich, Holinski-Feder, Elke, Kraft, Eduard, Dichgans, Martin, Brüning, Roland, Gasser, Thomas, Bötzel, Kai

“…Fragile X–associated tremor/ataxia syndrome (FXTAS) is a progressive adult‐onset tremor/ataxia syndrome caused by premutations in the FMR1 gene. In cranial…”
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Haplotype analysis of the human endogenous retrovirus locus HERV-K(HML-2.HOM) and its evolutionary implications by Mayer, Jens, Stuhr, Thomas, Reus, Katrin, Maldener, Esther, Kitova, Milena, Asmus, Friedrich, Meese, Eckart

“…We and others recently identified an almost-intact human endogenous retrovirus (HERV), termed HERV-K(HML-2.HOM), that is usually organized as a tandem…”
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Intravitreal Aflibercept Injection in Patients with Myopic Choroidal Neovascularization: The MYRROR Study by Ikuno, Yasushi, Ohno-Matsui, Kyoko, Wong, Tien Yin, Korobelnik, Jean-Francois, Vitti, Robert, Li, Tummy, Stemper, Brigitte, Asmus, Friedrich, Zeitz, Oliver, Ishibashi, Tatsuro

“…To evaluate intravitreal aflibercept 2 mg in patients with myopic choroidal neovascularization (CNV). An international, phase III, multicenter, randomized,…”
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Subunit expression of the cardiac L-type calcium channel is differentially regulated in diastolic heart failure of the cardiac allograft by HULLIN, R, ASMUS, F, LUDWIG, A, HERSEL, J, BOEKSTEGERS, P

“…Left ventricular diastolic dysfunction is a major cause of cardiac allograft failure. Multimeric L-type calcium channels (alpha1-, alpha2/delta-, and…”
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INTRAVITREAL NESVACUMAB (ANTIANGIOPOIETIN 2) PLUS AFLIBERCEPT IN DIABETIC MACULAR EDEMA: Phase 2 RUBY Randomized Trial by Brown, David M., Boyer, David S., Csaky, Karl, Vitti, Robert, Perlee, Lorah, Chu, Karen W., Asmus, Friedrich, Leal, Sergio, Zeitz, Oliver, Cheng, Yenchieh, Schmelter, Thomas, Heier, Jeffrey S.

“…The purpose of this study was to compare intravitreal nesvacumab (anti-angiopoietin 2) plus aflibercept with intravitreal aflibercept injection (IAI) in…”
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Ultrasound-guided injection of the iliopsoas muscle with botulinum toxin in camptocormia by von Coelln, Rainer, Raible, Armin, Gasser, Thomas, Asmus, Friedrich

“…Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco‐lumbar spine during standing and walking, which abates…”
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Intravitreal Nesvacumab (Anti-Angiopoietin 2) Plus Aflibercept in Diabetic Macular Edema: The Phase 2 RUBY Randomized Trial by Brown, David M., Boyer, David S., Csaky, Karl, Vitti, Robert, Perlee, Lorah, Chu, Karen W., Asmus, Friedrich, Leal, Sergio, Zeitz, Oliver, Cheng, Yenchieh, Schmelter, Thomas, Heier, Jeffrey S.

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A Missense Mutation in KCTD17 Causes Autosomal Dominant Myoclonus-Dystonia by Mencacci, Niccolo E., Rubio-Agusti, Ignacio, Zdebik, Anselm, Asmus, Friedrich, Ludtmann, Marthe H.R., Ryten, Mina, Plagnol, Vincent, Hauser, Ann-Kathrin, Bandres-Ciga, Sara, Bettencourt, Conceição, Forabosco, Paola, Hughes, Deborah, Soutar, Marc M.P., Peall, Kathryn, Morris, Huw R., Trabzuni, Daniah, Tekman, Mehmet, Stanescu, Horia C., Kleta, Robert, Carecchio, Miryam, Zorzi, Giovanna, Nardocci, Nardo, Garavaglia, Barbara, Lohmann, Ebba, Weissbach, Anne, Klein, Christine, Hardy, John, Pittman, Alan M., Foltynie, Thomas, Abramov, Andrey Y., Gasser, Thomas, Bhatia, Kailash P., Wood, Nicholas W.

“…Myoclonus-dystonia (M-D) is a rare movement disorder characterized by a combination of non-epileptic myoclonic jerks and dystonia. SGCE mutations represent a…”
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Spontaneous unwelcome orgasms due to pramipexole and ropinirole by Kaut, Oliver, Asmus, Friedrich, Paus, Sebastian

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Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor by THIER, Sandra, LORENZ, Delia, POEWE, Werner, ASMUS, Friedrich, GASSER, Thomas, SCHOLS, Ludger, CHRISTENSEN, Kaare, NEBEL, Almut, SCHREIBER, Stefan, KLEBE, Stephan, DEUSCHL, Günther, KUHLENBÄUMER, Gregor, NOTHNAGEL, Michael, POREMBA, Caroline, PAPENGUT, Frank, APPENZELLER, Silke, PASCHEN, Steffen, HOFSCHULTE, Frank, HUSSL, Anna-Christina, HERING, Sascha

“…Sporadic, genetically complex essential tremor (ET) is one of the most common movement disorders and may lead to severe impairment of the quality of life…”
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Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology by Zimprich, Alexander, Biskup, Saskia, Leitner, Petra, Lichtner, Peter, Farrer, Matthew, Lincoln, Sarah, Kachergus, Jennifer, Hulihan, Mary, Uitti, Ryan J., Calne, Donald B., Stoessl, A.Jon, Pfeiffer, Ronald F., Patenge, Nadja, Carbajal, Iria Carballo, Vieregge, Peter, Asmus, Friedrich, Müller-Myhsok, Bertram, Dickson, Dennis W., Meitinger, Thomas, Strom, Tim M., Wszolek, Zbigniew K., Gasser, Thomas

“…We have previously linked families with autosomal-dominant, late-onset parkinsonism to chromosome 12p11.2-q13.1 (PARK8). By high-resolution recombination…”
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