Search Results - "ASK, Birgitta"

Roles of Different CYP Enzymes in the Formation of Specific Fluvastatin Metabolites by Human Liver Microsomes by Toda, Takaki, Eliasson, Erik, Ask, Birgitta, Inotsume, Nobuo, Rane, Anders

“…:  Fluvastatin has been considered to be metabolised to 5‐hydroxy fluvastatin (M‐2), 6‐hydroxy fluvastatin (M‐3) and N‐desisopropyl fluvastatin (M‐5) in human…”
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Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation by Sten, Taina, Finel, Moshe, Ask, Birgitta, Rane, Anders, Ekström, Lena

“…Testosterone and epitestosterone are secreted mainly as glucuronide metabolites and the urinary ratio of testosterone glucuronide to epitestosterone…”
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The UGT2B17 gene deletion is not associated with prostate cancer risk by Olsson, Mats, Lindström, Sara, Häggkvist, Benjamin, Adami, Hans-Olov, Bälter, Katarina, Stattin, Pär, Ask, Birgitta, Rane, Anders, Ekström, Lena, Grönberg, Henrik

“…BACKGROUND Deletion polymorphism of the UDP‐glucuronosyltransferase 2B17 (UGT2B17) gene has been associated with an increased prostate cancer risk in two…”
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The effect of the CYP1A2 1F mutation on CYP1A2 inducibility in pregnant women by Nordmark, Anna, Lundgren, Stefan, Ask, Birgitta, Granath, Fredrik, Rane, Anders

“…Aims  To investigate the influence of the CYP1A2*1F mutation on CYP1A2 activity in smoking and nonsmoking pregnant women. Methods Pregnant women (n = 904) who…”
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Tricyclic antidepressants inhibit opioid receptor binding in human brain and hepatic morphine glucuronidation by Wahlström, A, Lenhammar, L, Ask, B, Rane, A

“…The opioid receptor binding in the human thalamic area was studied with U-69593 and naloxone as ligands for the kappa and mu receptors, respectively. The…”
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The effect of the CYPIA2 IF mutation on CYPIA2 inducibility in pregnant women by NORDMARK, Anna, LUNDGREN, Stefan, ASK, Birgitta, GRANATH, Fredrik, RANE, Anders

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Messenger ribonucleic acid levels of steroid 5α-reductase 2 in human prostate predict the enzyme activity by SODERSTROM, Torbjorn G, BJELFMAN, Catarina, BREKKAN, Einar, ASK, Birgitta, EGEVAD, Lars, NORLEN, Bo Johan, RANE, Anders

“…Testosterone is converted to dihydrotestosterone by 5 alpha-reductase2 in the prostate. Dihydrotestosterone controls cell division, and interindividual…”
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Messenger Ribonucleic Acid Levels of Steroid 5α-Reductase 2 in Human Prostate Predict the Enzyme Activity 1 by Söderström, Torbjörn G., Bjelfman, Catarina, Brekkan, Einar, Ask, Birgitta, Egevad, Lars, Norlén, Bo Johan, Rane, Anders

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Messenger Ribonucleic Acid Levels of Steroid 5α-Reductase 2 in Human Prostate Predict the Enzyme Activity1 by Söderström, Torbjörn G., Bjelfman, Catarina, Brekkan, Einar, Ask, Birgitta, Egevad, Lars, Norlén, Bo Johan, Rane, Anders

“…Testosterone is converted to dihydrotestosterone by 5α-reductase2 in the prostate. Dihydrotestosterone controls cell division, and interindividual differences…”
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The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme by Coughtrie, M W, Ask, B, Rane, A, Burchell, B, Hume, R

“…The formation of morphine glucuronides is enantio- and regioselective in rats and humans. In rat liver microsomes, natural (-)-morphine formed only the…”
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Insulin-like growth factor 1 (IGF-I) effects on sex-specific cytochrome P450 enzymes in normal and hypophysectomised male rats by Rasmussen, Eva, Ask, Birgitta, Finnström, Niklas, Skottner-Lundin, Anna, Rane, Anders

“…The role of growth hormone (GH) in the regulation of the sex-differentiated rat cytochrome P450 (CYP) enzymes has been extensively studied. However, little is…”
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A conspicuous down-regulating effect of morphine on essential steroid hydroxylation reactions and certain drug N-demethylations by Rane, A, Ask, B

“…This study was conducted to explore the potency of morphine to induce reductions of specific cytochrome P450 isoenzyme functions. Male Sprague-Dawley rats were…”
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Comparison of human fetal hepatic and adrenal cytochrome P450 activities with some major gestational steroids and ethylmorphine as substrates by Rane, A, Henningsson, S, Ask, B, Ladona, M G

“…The immunoidentified human fetal liver and adrenal microsomal contents of cytochromes P450IIIA and P450XVIIA1 were compared to the metabolism of steroids and…”
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The sensitivity to noxious heat in relation to brain and liver opioid glucuronidation in inbred strains of mice by Wahlström, Agneta, Lundin, Lars-Gustav, Ask, Birgitta, Rane, Anders

“…The glucuronidation of morphine and naloxone was demonstrated in the brain and liver in 2 inbred strains of mice, C57BL/6J (B6) and DBA/2J (D2) and their F1…”
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