Search Results - "ASHTON, D. S."

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation by Palmer, R M, Rees, D D, Ashton, D S, Moncada, S

“…The formation of nitric oxide (NO) from L-arginine by vascular endothelial cells and its relationship to endothelium-dependent relaxation of vascular rings was…”
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Constitutive and inducible nitric oxide synthases incorporate molecular oxygen into both nitric oxide and citrulline by LEONE, A. M, PALMER, R. M. J, KNOWLES, R. G, FRANCIS, P. L, ASHTON, D. S, MONCADA, S

“…Nitric oxide (NO) is synthesized by a number of cells from a guanidino nitrogen atom of L-arginine by the action of either constitutive or inducible NO…”
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Vascular endothelial cells synthesize nitric oxide from L-arginine by Palmer, R. M. J, Ashton, D. S, Moncada, S

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Characterization of fungal spores by laser desorption/ionization time-of-flight mass spectrometry by Welham, K. J., Domin, M. A., Johnson, K., Jones, L., Ashton, D. S.

“…A considerable volume of research has now been completed on the application of matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) to the…”
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Rapid validation of molecular structures of biological samples by electrospray-mass spectrometry by Ashton, D.S., Beddell, C.R., Green, B.N., Oliver, R.W.A.

“…A short account is presented of the method of measuring molecular masses ( M r) of pure biological samples by electrospray ionisation mass spectrometry. It is…”
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Detection of the principal synthetic route indicative impurity in Lamotrigine by Ashton, David S, Ray, Andrew D, Valko, Klara

“…An analytical method has been developed for the detection of trace amounts of the principal synthetic route indicative impurity in lamotrigine…”
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Vascular endothelial cells synthesize nitric oxide from L-arginine by Palmer, R M, Ashton, D S, Moncada, S

“…Nitric oxide (NO) released by vascular endothelial cells accounts for the relaxation of strips of vascular tissue and for the inhibition of platelet…”
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Mass Spectrometry of the Humanized Monoclonal Antibody Campath 1H by Ashton, David S, Beddell, Christopher R, Cooper, David J, Craig, Sarah J, Lines, Anne C, Oliver, Ronald W. A, Smith, Marjorie A

“…Two mass spectrometric techniques, electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI) have been used to study the intact…”
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On the analysis of bovine trypsin by electrospray-mass spectrometry by Ashton, D S, Ashcroft, A E, Beddell, C R, Cooper, D J, Green, B N, Oliver, R W

“…In this paper the results obtained from an electrospray mass spectrometric (ES-MS) analytical study of commercial grade bovine trypsin are presented and…”
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The characterization of micro-organisms by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by Welham, Kevin J., Domin, Mark A., Scannell, D. Eoin, Cohen, E., Ashton, David S.

“…A variety of gram‐positive and gram‐negative intact bacterial cells have been analysed by matrix‐assisted laser desorption/ionization mass spectrometry…”
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Some electrospray mass spectrometric evidence for the existence of covalent O-acyl enzyme intermediates by Ashton, David S., Beddell, Christopher R., Cooper, David J., Green, Brian N., Oliver, Ronald W.A., Welham, Kevin J.

“…Electrospray mass spectrometry has been used to measure the masses of the species present in solutions of three serine proteases (α-chymotrypsin, subtilisin…”
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The effect of solvent and matrix combinations on the analysis of bacteria by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry by Domin, Mark A., Welham, Kevin J., Ashton, David S.

“…The ability to rapidly identify the taxonomic class of the wide variety of microorganisms involved in human and animal disease is becoming increasingly…”
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Combined gas chromatography-infra-red spectroscopy for the determination of propanediol in acyclovir cream by GILBERT, A. S, MOSS, C. J, FRANCIS, P. L, ASHTON, M. J, ASHTON, D. S

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Binding measurements of indolocarbazole derivatives to immobilised human serum albumin by high-performance liquid chromatography by Ashton, D.S., Beddell, C.R., Cockerill, G.S., Gohil, K., Gowrie, C., Robinson, J.E., Slater, M.J., Valko, K.

“…The binding properties of six indolocarbazole derivatives have been measured using immobilised human serum albumin (HSA) in an HPLC column. The compounds…”
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Lipids present in olive skin by Milosevic, Jelena, Ashton, David S., Cocksedge, Michael J.

“…Olive oil is a major constituent of many food preparations and is used in margarine and as a cooking oil. Olive oil consists of lipidic components, mainly…”
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Thermospray tandem mass spectrometric analysis of oxygen incorporation into citrulline by nitric oxide synthase by Leone, A M, Francis, P L, Palmer, R M, Ashton, D S, Moncada, S

“…Citrulline is formed as a co-product in the biosynthesis of nitric oxide from L-arginine by the action of either constitutive or inducible nitric oxide…”
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Quantitative structure-retention relationships of acyclovir esters using immobilised albumin high-performance liquid chromatography and reversed-phase high-performance liquid chromatography by Ashton, D.S., Beddell, C., Ray, A.D., Valkó, K.

“…Acyclovir and 18 of its esters have been investigated by systematic measurement of their reversed-phase high-performance liquid chromatographic retention using…”
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Determination of carbohydrate heterogeneity in the humanised antibody CAMPATH 1H by liquid chromatography and matrix-assisted laser desorption ionisation mass spectrometry by Ashton, David S., Beddell, Christopher R., Cooper, David J., Lines, Anne C.

“…The carbohydrate heterogeneity in a humanised immunoglobulin CAMPATH 1H has been evaluated by liquid chromatography (LC) and matrix-assisted laser desorption…”
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On the purity of 3X-recrystallized bovine alpha-chymotrypsin by Ashton, D S, Beddell, C R, Cooper, D J, Green, B N, Oliver, R W, Welham, K J

“…The results of an electrospray-mass spectrometric analytical study of aqueous solutions of fifteen commercial samples of 3X-recrystallized bovine…”
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Neurally mediated syncope : pathogenesis, diagnosis, and treatment by KAUFMANN, H

“…Neurally mediated syncope is the most frequent cause of syncope in patients who do not have structural heart disease. Neurally mediated syncope is believed to…”
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