Search Results - "ASHLEY, David"
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Management of glioblastoma: State of the art and future directions
Published in CA: a cancer journal for clinicians (01-07-2020)“…Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for patients with this disease is poor, with a median survival of <2…”
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Brain immunology and immunotherapy in brain tumours
Published in Nature reviews. Cancer (01-01-2020)“…Gliomas, the most common malignant primary brain tumours, remain universally lethal. Yet, seminal discoveries in the past 5 years have clarified the anatomy,…”
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Adapting to a Pandemic - Conducting Oncology Trials during the SARS-CoV-2 Pandemic
Published in Clinical cancer research (01-07-2020)“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has necessitated changes in cancer care delivery as resources are reallocated…”
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Are electronic nicotine delivery systems helping cigarette smokers quit? Evidence from a prospective cohort study of U.S. adult smokers, 2015-2016
Published in PloS one (09-07-2018)“…The potential of electronic nicotine delivery systems (ENDS) to reduce the cardiovascular and other disease risks of smoking is of great interest. While many…”
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Evolution of tobacco products: recent history and future directions
Published in Tobacco control (01-03-2022)“…Declines in cigarette smoking prevalence in many countries and the consolidation of the tobacco industry have prompted the introduction of other forms of…”
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Bourbon Virus in Field-Collected Ticks, Missouri, USA
Published in Emerging infectious diseases (01-12-2017)“…Bourbon virus (BRBV) was first isolated in 2014 from a resident of Bourbon County, Kansas, USA, who died of the infection. In 2015, an ill Payne County,…”
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JUUL releases more nicotine in the first puffs
Published in Tobacco control (01-03-2023)Get more information
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Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI/MSMS)
Published in Analytica chimica acta (31-10-2012)“…[Display omitted] ► We developed an UPLC-ESI/MSMS method to measure 28 urinary VOC metabolites. ► This high throughput method is precise, accurate and…”
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The Paradoxical Effects of COVID-19 on Cancer Care: Current Context and Potential Lasting Impacts
Published in Clinical cancer research (15-11-2020)“…Coronavirus disease 2019 (COVID-19) has fundamentally disrupted the practice of oncology, shifting care onto virtual platforms, rearranging the logistics and…”
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"I'm Bored and I'm Stressed": A Qualitative Study of Exclusive Smokers, ENDS Users, and Transitioning Smokers or ENDS Users in the Time of COVID-19
Published in Nicotine & tobacco research (05-01-2023)“…To better understand the various influences of COVID-19 on tobacco use, we examined three different tobacco user groups using qualitative methods. Ten online…”
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Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling
Published in Nature communications (25-03-2021)“…Activating intra-tumor innate immunity might enhance tumor immune surveillance. Virotherapy is proposed to achieve tumor cell killing, while indirectly…”
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First detection of heartland virus (Bunyaviridae: Phlebovirus) from field collected arthropods
Published in The American journal of tropical medicine and hygiene (01-09-2013)“…Heartland virus (HRTV), the first pathogenic Phlebovirus (Family: Bunyaviridae) discovered in the United States, was recently described from two Missouri…”
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13
IQOS debut in the USA: Philip Morris International's heated tobacco device introduced in Atlanta, Georgia
Published in Tobacco control (01-12-2020)Get more information
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14
What is the burden of proof for tumor mutational burden in gliomas?
Published in Neuro-oncology (Charlottesville, Va.) (30-11-2020)“…Abstract The treatment of patients with a variety of solid tumors has benefitted from immune checkpoint inhibition targeting the anti-programmed cell death-1…”
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Assessing secondhand smoke using biological markers
Published in Tobacco control (01-05-2013)“…Secondhand smoke exposure (SHSe) is a known cause of many adverse health effects in adults and children. Increasingly, SHSe assessment is an element of tobacco…”
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The integrated genomic and epigenomic landscape of brainstem glioma
Published in Nature communications (17-06-2020)“…Brainstem gliomas are a heterogeneous group of tumors that encompass both benign tumors cured with surgical resection and highly lethal cancers with no…”
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Gene expression analysis suggests immunosuppressive roles of endolysosomes in glioblastoma
Published in PloS one (20-03-2024)“…Targeting endolysosomes is a strategy extensively pursued for treating cancers, including glioblastomas (GBMs), on the basis that the intact function of these…”
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Cluster analysis of urinary tobacco biomarkers among U.S. adults: Population Assessment of Tobacco and Health (PATH) biomarker study (2013–2014)
Published in Preventive medicine (01-11-2020)“…Tobacco use delivers nicotine, tobacco-specific nitrosamines (TSNAs), volatile organic compounds (VOCs), and polycyclic aromatic hydrocarbons (PAHs), which are…”
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Mechanisms of telomere maintenance and associated therapeutic vulnerabilities in malignant gliomas
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2024)“…A majority of cancers (~85%) activate the enzyme telomerase to maintain telomere length over multiple rounds of cellular division. Telomerase-negative cancers…”
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Weight regulation and bone mass: a comparison between professional jockeys, elite amateur boxers, and age, gender and BMI matched controls
Published in Journal of bone and mineral metabolism (01-03-2012)“…The aim of this study was to compare bone mass between two groups of jockeys (flat: n = 14; national hunt: n = 16); boxers ( n = 14) and age, gender and BMI…”
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