Search Results - "ASHENDEL, C"
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Kinase Inhibitors from Polygonum cuspidatum
Published in Journal of natural products (Washington, D.C.) (01-10-1993)“…Bioassay-directed fractionation of a medicinal plant, Polygonum cuspidatum (Polygonaceae), has led to the discovery of a hydroxystilbene, resveratrol [1], as…”
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2
Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis
Published in Molecular and Cellular Biology (01-07-1997)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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3
Novel protein kinase C inhibitors: α-terthiophene derivatives
Published in Bioorganic & medicinal chemistry letters (06-10-1998)“…A series of α-terthiophene derivatives were prepared and their protein kinase C inhibitory activity were evaluated. The aldehyde derivatives were most potent…”
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4
Novel protein kinase C inhibitors: synthesis and PKC inhibition of β-substituted polythiophene derivatives
Published in Bioorganic & medicinal chemistry letters (02-08-1999)“…A series of β-substituted polythiophene derivatives was synthesized through palladium-catalyzed coupling reaction. Their structure-protein kinase C (PKC)…”
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5
Workgroup 3: Transgenic and reconstitution models of prostate cancer
Published in The Prostate (15-06-1998)Get full text
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The phorbol ester receptor: a phospholipid-regulated protein kinase
Published in Biochimica et biophysica acta (09-09-1985)Get more information
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7
Oncogene signal transduction inhibitors from Chinese medicinal plants
Published in Pure and applied chemistry (30-06-1999)“…Abstract…”
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8
Differing modulation of protein kinase C by bryostatin 1 and phorbol esters in JB6 mouse epidermal cells
Published in The Journal of biological chemistry (15-06-1988)“…Bryostatin 1 (Bryo), a macrocyclic lactone, stimulates some but not all of the biologic effects which are induced by phorbol esters (PEs). In vitro, it…”
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9
Diet, signal transduction and carcinogenesis
Published in The Journal of nutrition (01-03-1995)“…The defects in the regulation of cell growth and differentiation that manifest themselves as cancer result from multiple defective genes and their products,…”
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10
Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk
Published in Biochimica et biophysica acta (04-02-1997)“…The protein tyrosine kinase p72 syk (Syk) is expressed in a variety of hematopoietic cell types, including B cells, thymocytes, mast cells and others. Both the…”
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11
A multiwell assay for inhibitors of phosphatidylinositol-3-kinase and the identification of natural product inhibitors
Published in Anticancer research (01-11-1994)“…A convenient and reliable multisample assay for the screening of inhibitors of the growth factor signalling enzyme phosphatidylinositol-3-kinase (PtdIns-3-K)…”
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12
Inhibition of Myogenesis by the H-ras Oncogene: Implication of a Role for Protein Kinase C
Published in The Journal of cell biology (01-08-1991)“…Expression of the oncogenic form of H-ras p21 in the mouse myogenic cell line, 23A2, blocks myogenesis and inhibits expression of the myogenic regulatory…”
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13
Protein kinase activity associated with a phorbol ester receptor purified from mouse brain
Published in Cancer research (Chicago, Ill.) (01-09-1983)“…Protein kinase activity copurified with the receptor for 12-O-[3H]tetradecanoylphorbol-13-acetate during its purification from mouse brain particulate protein…”
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14
Inhibition of intracellular Ca2+ signalling, cytotoxicity and antitumor activity of the herbicide oryzalin and its analogues
Published in Cancer chemotherapy and pharmacology (1997)“…Studies were conducted on oryzalin (3,5-dinitro-N,N-di(n-propyl)sulfanilamide), a widely used dinitroaniline sulfonamide herbicide, which was identified from…”
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15
Isolation and Characterization of the Principal ATPase Associated with Transitional Endoplasmic Reticulum of Rat Liver
Published in The Journal of cell biology (01-12-1994)“…The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough,…”
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16
Hemicholinium and related lipids: inhibitors of protein kinase C
Published in Journal of medicinal chemistry (1993)Get full text
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17
Isolation of cloned mouse protein kinase C beta-II cDNA and its sequence
Published in Nucleic acids research (11-09-1990)“…We have utilized synthetic oligonucleotides based on the sequences of rat protein kinase C (PKC)- beta and rat PKC- gamma to isolate cloned cDNA from a…”
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18
Increased intracellular Ca2+ signaling caused by the antitumor agent helenalin and its analogues
Published in Cancer chemotherapy and pharmacology (1994)“…The antitumor sesquiterpene lactone helenalin, which is found in species of the plant genus Helenium, caused a marked potentiation of the increases in…”
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Activation of T Cell Raf-1 at Mitosis Requires the Protein-tyrosine Kinase Lck
Published in The Journal of biological chemistry (29-11-1996)“…The serine/threonine protein kinase Raf-1 is activated in response to a variety of growth factors in fibroblasts and hematopoietic cells. In T cells, Raf-1 is…”
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Advances with phospholipid signalling as a target for anticancer drug development
Published in Acta biochimica polonica (01-01-1995)“…The phosphatidylinositol-3-kinases (PtdIns-3-kinase) are a family of enzymes involved in the control of cell replication. One member of the family, the…”
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