Search Results - "ASHCROFT, G"

Effects of the COVID-19 lockdown on orthopaedic trauma: a multicentre study across Scotland by MacDonald, David R W, Neilly, David W, Davies, Peter S E, Crome, Christopher R, Jamal, Bilal, Gill, Sarah L, Jariwala, Arpit C, Stevenson, Iain M, Ashcroft, G Patrick

“…The UK government declared a national lockdown on 23 March 2020 to reduce transmission of COVID-19. This study aims to identify the effect of lockdown on the…”
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Factors influencing patient uptake of an exercise referral scheme: a qualitative study by Birtwistle, S B, Ashcroft, G, Murphy, R, Gee, I, Poole, H, Watson, P M

“…Abstract Exercise referral schemes aim to increase physical activity amongst inactive individuals with or at risk of long-term health conditions. Yet many…”
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Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland by Brewster, D H, Stockton, D L, Reekie, A, Ashcroft, G P, Howie, C R, Porter, D E, Black, R J

“…Background: Release and dispersion of particles arising from corrosion and wear of total hip arthroplasty (THA) components has raised concerns about a possible…”
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Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice by Waite, A., Gilliver, S. C., Masterson, G. R., Hardman, M. J., Ashcroft, G. S.

“…Background Lidocaine and bupivacaine are commonly infiltrated into surgical cutaneous wounds to provide local anaesthesia after surgical procedures. However,…”
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5α-Dihydrotestosterone (DHT) retards wound closure by inhibiting re-epithelialization by Gilliver, SC, Ruckshanthi, JPD, Hardman, MJ, Zeef, LAH, Ashcroft, GS

“…The ongoing search for explanations as to why elderly males heal acute skin wounds more slowly than do their female counterparts (and are more strongly…”
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Topical photodynamic therapy following excisional wounding of human skin increases production of transforming growth factor-β3 and matrix metalloproteinases 1 and 9, with associated improvement in dermal matrix organization by Mills, S.J., Farrar, M.D., Ashcroft, G.S., Griffiths, C.E.M., Hardman, M.J., Rhodes, L.E.

“…Summary Background Animal studies report photodynamic therapy (PDT) to improve healing of excisional wounds; the mechanism is uncertain and equivalent human…”
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Prioritization of THose aWaiting hip and knee ArthroplastY(PATHWAY): protocol for development of a stakeholder led clinical prioritization tool by Farrow, Luke, Clement, Nick D, Smith, Diane, Meek, Dominic R M, Ryan, Mandy, Gillies, Katie, Anderson, Lesley, Ashcroft, G P

“…The extended wait that most patients are now experiencing for hip and knee arthroplasty has raised questions about whether reliance on waiting time as the…”
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Bidirectional regulation of macrophage function by TGF-β by Ashcroft, Gillian S.

“…The dual role of transforming growth factor-beta (TGF-β) in modulating macrophage function is an important concept gaining increasing recognition. In addition…”
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Intraoperative changes in platelet function in relation to moderate haemorrhage by Hetherington, Jonathan J, Ford, Isobel, Ashcroft, G. Patrick, Jansen, Jan O

“…Abstract Background Haemorrhage is associated with haemostatic dysfunction. Previous studies have focused on coagulation factors, but platelet function plays…”
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Topical Estrogen Accelerates Cutaneous Wound Healing in Aged Humans Associated with an Altered Inflammatory Response by Ashcroft, Gillian S., Greenwell-Wild, Teresa, Horan, Michael A., Wahl, Sharon M., Ferguson, Mark W.J.

“…The effects of intrinsic aging on the cutaneous wound healing process are profound, and the resulting acute and chronic wound morbidity imposes a substantial…”
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Sex steroids and cutaneous wound healing: the contrasting influences of estrogens and androgens by Gilliver, S. C., Ashcroft, G. S.

“…The increased prevalence in the elderly of chronic wound-healing conditions, such as venous and diabetic ulceration, is firmly established. This same…”
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Study of the preparation conditions for NiMn2O4 grown from hydroxide precursors by ASHCROFT, G, TERRY, I, GOVER, R

“…An investigation of mixed oxide route preparation routes for nickel manganite has confirmed that residual nickel oxide is present regardless of the particular…”
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Convection warmers—a possible source of contamination in laminar airflow operating theatres? by Tumia, N., Ashcroft, G.P.

“…This work results from concerns that forced-air convection heaters applied to patients in the operating theatre might interfere with ultra-clean ventilation…”
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Conversion of Proepithelin to Epithelins: Roles of SLPI and Elastase in Host Defense and Wound Repair by Zhu, Jing, Nathan, Carl, Jin, Wenwen, Sim, Davis, Ashcroft, Gillian S., Wahl, Sharon M., Lacomis, Lynne, Erdjument-Bromage, Hediye, Tempst, Paul, Wright, Clifford D., Ding, Aihao

“…Increased leukocyte elastase activity in mice lacking secretory leukocyte protease inhibitor (SLPI) leads to impaired wound healing due to enhanced activity of…”
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Aging Is Associated with Reduced Deposition of Specific Extracellular Matrix Components, an Upregulation of Angiogenesis, and an Altered Inflammatory Response in a Murine Incisional Wound Healing Model by Ashcroft, Gillian S., Horan, Michael A., Ferguson, Mark W.J.

“…The concept that aging impairs wound healing is largely unsubstantiated, the literature being contradictory because of poor experimental design and a failure…”
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Polymorphisms spanning the 0N exon and promoter of the estrogen receptor-beta (ERβ) gene ESR2 are associated with venous ulceration by Ashworth, JJ, Smyth, JV, Pendleton, N, Horan, M, Payton, A, Worthington, J, Ollier, WE, Ashcroft, GS

“…Venous ulcers are characterized by excessive inflammation and raised levels of proinflammatory cytokines. Estrogen has been shown to accelerate the rate of…”
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Reverse LISS plating for proximal segmental femoral fractures in the polytrauma patient: A case report by Pryce Lewis, J.R, Ashcroft, G.P

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Femoral Head Viability After Birmingham Resurfacing Hip Arthroplasty: Assessment with Use of [18F] Fluoride Positron Emission Tomography by Forrest, N, Welch, A, Murray, A.D, Schweiger, L, Hutchison, J, Ashcroft, G.P

“…BackgroundTotal hip resurfacing has become increasingly popular over the last decade. There remains concern about the effect of the surgical approach on…”
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Aging alters the inflammatory and endothelial cell adhesion molecule profiles during human cutaneous wound healing by Ashcroft, G S, Horan, M A, Ferguson, M W

“…Age-related changes in the human inflammatory response in vivo have been largely ignored, resulting in a lack of understanding of the patho-physiologic…”
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A numerical investigation of the noise radiated by a turbulent flow over a cavity by Ashcroft, G.B, Takeda, K, Zhang, X

“…The tonal noise radiated by a two-dimensional cavity submerged in a low-speed turbulent flow has been investigated computationally using a hybrid scheme that…”
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