Search Results - "ASFA, Sima"

Reduction of AMP-Activated Protein Kinase α2 Increases Endoplasmic Reticulum Stress and Atherosclerosis In Vivo by YUNZHOU DONG, MIAO ZHANG, BIN LIANG, ZHONGLIN XIE, ZHENGXING ZHAO, ASFA, Sima, HYOUNG CHUL CHOI, ZOU, Ming-Hui

“…Background— Aberrant endoplasmic reticulum (ER) stress is associated with several cardiovascular diseases, including atherosclerosis. The mechanism by which…”
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Gold Nanoparticles Disrupt the IGFBP2/mTOR/PTEN Axis to Inhibit Ovarian Cancer Growth by Hossen, Md. Nazir, Wang, Lin, Dwivedi, Shailendra Kumar Dhar, Zhang, Yushan, Rao, Geeta, Elechalwar, Chandra Kumar, Sheth, Vinit, Dey, Anindya, Asfa, Sima, Gulla, Suresh Kumar, Xu, Chao, Fung, Kar‐Ming, Robertson, J. David, Bieniasz, Magdalena, Wilhelm, Stefan, Bhattacharya, Resham, Mukherjee, Priyabrata

“…By exploiting the self‐therapeutic properties of gold nanoparticles (GNPs) a molecular axis that promotes the growth of high‐grade serous ovarian cancer…”
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Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors by Xu, Jian, Wang, Shuangxi, Zhang, Miao, Wang, Qilong, Asfa, Sima, Zou, Ming-Hui

“…Oxidative stress is believed to cause endothelial dysfunction, an early event and a hallmark in cardiovascular diseases (CVD) including hypertension, diabetes,…”
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Degree of modification of Ro60 by the lipid peroxidation by-product 4-hydroxy-2-nonenal may differentially induce Sjögren syndrome or systemic lupus erythematosus in BALB/c mice by Kurien, Biji T., Porter, Andrew, Dorri, Yaser, Iqbal, Saqib, D'Souza, Anil, Singh, Anil, Asfa, Sima, Cartellieri, Marc, Mathias, Kristen, Matsumoto, Hiroyuki, Bachmann, Michael, Hensley, Kenneth, Scofield, R. Hal

“…Our previous work showed that immunization of rabbits with 4-hydroxy-2-nonenal-modified Ro60 (HNE-Ro60) accelerates autoimmunity. We extended this model into…”
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Correction to “Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation” by Elechalawar, Chandra Kumar, Rao, Geeta, Gulla, Suresh Kumar, Patel, Maulin Mukeshchandra, Frickenstein, Alex, Means, Nicolas, Roy, Ram Vinod, Tsiokas, Leonidas, Asfa, Sima, Panja, Prasanta, Rao, Chinthalapally, Wilhelm, Stefan, Bhattacharya, Resham, Mukherjee, Priyabrata

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Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation by Elechalawar, Chandra Kumar, Rao, Geeta, Gulla, Suresh Kumar, Patel, Maulin Mukeshchandra, Frickenstein, Alex, Means, Nicolas, Roy, Ram Vinod, Tsiokas, Leonidas, Asfa, Sima, Panja, Prasanta, Rao, Chinthalapally, Wilhelm, Stefan, Bhattacharya, Resham, Mukherjee, Priyabrata

“…The RAS-transformed cells utilize macropinocytosis to acquire amino acids to support their uncontrolled growth. However, targeting RAS to inhibit…”
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Pancreatic Ubap2 deletion regulates glucose tolerance, inflammation, and protection from cerulein-induced pancreatitis by Roy, Ram Vinod, Means, Nicolas, Rao, Geeta, Asfa, Sima, Madka, Venkateshwar, Dey, Anindya, Zhang, Yushan, Choudhury, Monalisa, Fung, Kar-Ming, Dhanasekaran, Danny N., Friedman, Jacob E., Crawford, Howard C., Rao, Chinthalapally V., Bhattacharya, Resham, Mukherjee, Priyabrata

“…Ubiquitin-binding associated protein 2 (UBAP2) is reported to promote macropinocytosis and pancreatic adenocarcinoma (PDAC) growth, however, its role in normal…”
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Disabling partners in crime: Gold nanoparticles disrupt multicellular communications within the tumor microenvironment to inhibit ovarian tumor aggressiveness by Zhang, Yushan, Elechalawar, Chandra Kumar, Yang, Wen, Frickenstein, Alex N., Asfa, Sima, Fung, Kar-Ming, Murphy, Brennah N., Dwivedi, Shailendra K, Rao, Geeta, Dey, Anindya, Wilhelm, Stefan, Bhattacharya, Resham, Mukherjee, Priyabrata

“…[Display omitted] •Cocultured EC and CAF promote CC proliferation.•20 nm GNP inhibit the growth of CC cocultured with EC and CAF.•Supernatant of CC, EC & CAF…”
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Immunization with Short Peptides from the 60-kDa Ro Antigen Recapitulates the Serological and Pathological Findings as well as the Salivary Gland Dysfunction of Sjogren's Syndrome by Scofield, R. Hal, Asfa, Sima, Obeso, David, Jonsson, Roland, Kurien, Biji T

“…Sjögren's syndrome is a poorly understood autoimmune inflammatory illness that affects the salivary and lacrimal glands as well as other organ systems. We…”
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Knockdown of DCAMKL-1 Results in Liver Cancer Tumor Growth Arrest Through Inhibition of c-MYC via Let-7a MicroRNA; Inhibits EMT via Mir-200a MicroRNA Dependent Mechanisms by Sureban, Sripathi M, Qu, Dongfeng, May, Randal, Asfa, Sima, Anant, Shrikant, Houchen, Courtney W

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Knockdown of Musashi-1 Results in Tumor Growth Arrest Through Inhibition of c-MYC, Notch-1 and EMT by Let-7a, Mir-144 and Mir-200a MicroRNAs Dependent Mechanisms Respectively by Sureban, Sripathi M, May, Randal, Qu, Dongfeng, Asfa, Sima, Anant, Shrikant, Houchen, Courtney W

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Reduction of AMP-activated Protein Kinase Alpha 2 Increases Endoplasmic Reticulum Stress and Atherosclerosis In Vivo by Dong, Yunzhou, Zhang, Miao, Liang, Bin, Xie, Zhonglin, Zhao, Zhengxing, Asfa, Sima, Choi, Hyoung Chul, Zou, Ming-Hui

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Nanoparticle-Based Delivery of DCAMKL-1 SiRNA and DAPT Increases MicroRNA-144 and Inhibits Colorectal Cancer Tumor Growth via a Notch-1 Dependent Mechanism by Sureban, Sripathi M, May, Randal, Qu, Dongfeng, Mondalek, Fadee G, Asfa, Sima, Ramanujam, Rama, Anant, Shrikant, Houchen, Courtney W

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Comparative Evaluation of Novel Putative Stem Cell Markers and Tumor Suppressor MicroRNAs in Barrett's Esophagus by Qu, Dongfeng, Sureban, Sripathi M, May, Randal, Asfa, Sima, Meltzer, Stephen J, Anant, Shrikant, Houchen, Courtney W

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Degree of modification of Ro60 by the lipid peroxidation by-product 4-hydroxy-2-nonenal may differentially induce Sjögren's syndrome or systemic lupus erythematosus in BALB/c mice by Kurien, Biji T., Porter, Andrew, Dorri, Yaser, Iqbal, Saqib, D'Souza, Anil, Singh, Anil, Asfa, Sima, Cartellieri, Marc, Matsumoto, Hiroyuki, Bachmann, Michael, Hensley, Kenneth, Scofield, R. Hal

“…Our previous work showed that immunization of rabbits with 4-hydroxy 2-nonenal-modified Ro60 (HNE-Ro60) accelerates autoimmunity. We extended this model into…”
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OR.34. Adoptive Transfer of Ro Pepitde Induced Experimental Sjogren's Syndrome by Scofield, Hal, Asfa, Sima, D'Sousa, Anil, Dori, Yasar, Kurien, Biji

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Immunization with Short Peptides from the 60-kDa Ro Antigen Recapitulates the Serological and Pathological Findings as well as the Salivary Gland Dysfunction of Sjögren’s Syndrome by Scofield, R. Hal, Asfa, Sima, Obeso, David, Jonsson, Roland, Kurien, Biji T.

“…Sjögren’s syndrome is a poorly understood autoimmune inflammatory illness that affects the salivary and lacrimal glands as well as other organ systems. We…”
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Immunization with Short Peptides from the 60-kDa Ro Antigen Recapitulates the Serological and Pathological Findings as well as the Salivary Gland Dysfunction of Sjoegren's Syndrome by Scofield, RHal, Asfa, Sima, Obeso, David, Jonsson, Roland, Kurien, Biji T

“…Sjoegren's syndrome is a poorly understood autoimmune inflammatory illness that affects the salivary and lacrimal glands as well as other organ systems. We…”
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Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo by Dong, Yunzhou, Zhang, Miao, Liang, Bin, Xie, Zhonglin, Zhao, Zhengxing, Asfa, Sima, Choi, Hyoung Chul, Zou, Ming-Hui

“…Aberrant endoplasmic reticulum (ER) stress is associated with several cardiovascular diseases, including atherosclerosis. The mechanism by which aberrant ER…”
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