Search Results - "ASAO, ATSUKO"
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ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity
Published in Cell reports (Cambridge) (21-02-2017)“…Obesity represents chronic inflammatory states promoted by pro-inflammatory M1-macrophage infiltration into white adipose tissue (WAT), thereby inducing…”
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GITR controls intestinal inflammation by suppressing IL‐15‐dependent NK cell activity
Published in The FASEB journal (01-11-2020)“…Glucocorticoid‐induced TNFR family related gene (GITR) is a member of the TNFR superfamily that is expressed on cells of the immune system. Although the…”
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The Curcumin Analog GO-Y030 Controls the Generation and Stability of Regulatory T Cells
Published in Frontiers in immunology (23-06-2021)“…Regulatory T cells (Tregs) play a crucial role in preventing antitumor immune responses in cancer tissues. Cancer tissues produce large amounts of transforming…”
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Germ-Free Conditions Modulate Host Purine Metabolism, Exacerbating Adenine-Induced Kidney Damage
Published in Toxins (26-08-2020)“…Alterations in microbiota are known to affect kidney disease conditions. We have previously shown that germ-free conditions exacerbated adenine-induced kidney…”
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IQ motif-containing GTPase-activating protein 1 is essential for the optimal maintenance of lung ILC2s
Published in International immunology (12-04-2020)“…Abstract Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory…”
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TNF Receptor-Associated Factor 5 Limits Function of Plasmacytoid Dendritic Cells by Controlling IFN Regulatory Factor 5 Expression
Published in The Journal of immunology (1950) (15-09-2019)“…The physiological functions of TNF receptor-associated factor 5 (TRAF5) in the skin inflammation and wound healing process are not well characterized. We found…”
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CD45 + CD326 + Cells are Predictive of Poor Prognosis in Non-Small Cell Lung Cancer Patients
Published in Clinical cancer research (15-11-2019)“…The epithelial-to-mesenchymal transition, the major process by which some cancer cells convert from an epithelial phenotype to a mesenchymal one, has been…”
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TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation
Published in Biochemical and biophysical research communications (15-05-2018)“…Oncostatin M (OSM) is involved in pathogenesis of several human inflammatory diseases including lung inflammation and fibrosis. Although accumulating evidence…”
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Mesenteric lymph nodes contribute to proinflammatory Th17‐cell generation during inflammation of the small intestine in mice
Published in European journal of immunology (01-05-2016)“…T cells of the small intestine, including Th17 cells, are critically involved in host protection from microbial infection, and also contribute to the…”
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Costello syndrome model mice with a Hras G12S mutation are susceptible to develop house dust mite-induced atopic dermatitis
Published in Cell death & disease (13-08-2020)“…Costello syndrome is an autosomal dominant disorder that is caused by germline HRAS mutations. Patients with Costello syndrome present craniofacial…”
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Y chromosome-linked B and NK cell deficiency in mice
Published in The Journal of immunology (1950) (15-06-2013)“…There are no primary immunodeficiency diseases linked to the Y chromosome, because the Y chromosome does not contain any vital genes. We have established a…”
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Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector
Published in PloS one (21-08-2013)“…X-linked severe combined immunodeficiency (SCID-X1) is an inherited genetic immunodeficiency associated with mutations in the common cytokine receptor γ chain…”
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Correction: TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells
Published in ImmunoHorizons (23-04-2020)Get full text
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TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells
Published in ImmunoHorizons (10-03-2020)“…TNFR-associated factor 5 (TRAF5) is a cytosolic adaptor protein and functions as an inflammatory regulator. However, the in vivo function of TRAF5 remains…”
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Fatty acid‐binding protein 3 controls contact hypersensitivity through regulating skin dermal Vγ4+ γ/δ T cell in a murine model
Published in Allergy (Copenhagen) (01-06-2021)“…Background Fatty acid‐binding protein 3 (FABP3) is a cytosolic carrier protein of polyunsaturated fatty acids (PUFAs) and regulates cellular metabolism…”
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IQ motif-containing GTPase-activating protein 1 is essential for the optimal maintenance of lung ILC2s
Published in The Journal of immunology (1950) (01-05-2020)“…Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory disease. IQ…”
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The adaptor TRAF5 limits the differentiation of inflammatory CD4+ T cells by antagonizing signaling via the receptor for IL-6
Published in Nature immunology (01-05-2014)“…Adaptors of the TRAF family are tumor-necrosis factor receptor–associated factors. So and colleagues show that TRAF5 negative regulates the IL-6 receptor…”
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Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells
Published in The Journal of immunology (1950) (01-06-2013)“…Homeostatic proliferation of naive T cells in the spleen and cutaneous lymph nodes supplies memory-phenotype T cells. The "systemic" proliferative responses…”
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The adaptor TRAF5 limits the differentiation of inflammatory [CD4.sup.+] T cells by antagonizing signaling via the receptor for IL-6
Published in Nature immunology (01-05-2014)“…The physiological functions of members of the tumor-necrosis factor (TNF) receptor (TNFR)-associated factor (TRAF) family in T cell immunity are not well…”
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The adaptor TRAF5 limits the differentiation of inflammatory CD4 super(+) T cells by antagonizing signaling via the receptor for IL-6
Published in Nature immunology (01-05-2014)“…The physiological functions of members of the tumor-necrosis factor (TNF) receptor (TNFR)-associated factor (TRAF) family in T cell immunity are not well…”
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