Search Results - "ASANO, Norihide"
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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-07-2015)“…•JaCVAM organized an international validation study of in vivo rat comet assay.•The ultimate goal was to establish the OECD test guideline.•The assay…”
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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-07-2015)“…•JaCVAM-organized an international validation study of in vivo rat comet assay.•The ultimate goal was to establish the OECD test guideline.•The study protocol…”
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Practical threshold for micronucleated reticulocyte induction observed for low doses of mitomycin C, Ara-C and colchicine
Published in Mutagenesis (01-01-2006)“…Micronucleus induction was studied for the DNA target clastogens mitomycin C (MMC) and 1-β-D-arabinofuranosylcytosine (Ara-C), and also the non-DNA target…”
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Evaluation of the rodent micronucleus assay by a 28-day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)-Mammalian Mutagenicity Study Group (MMS)
Published in Environmental and molecular mutagenesis (2001)“…To examine whether micronucleus tests can be incorporated into general toxicology assays, we performed micronucleus tests applying the treatment protocols…”
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In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test
Published in Mutation research (03-02-2007)“…The in vivo micronucleus assay working group of the International Workshop on Genotoxicity Testing (IWGT) discussed new aspects in the in vivo micronucleus…”
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Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes: I. Intra- and Interlaboratory Comparison with Microscopic Scoring
Published in Toxicological sciences (01-11-2006)“…Accumulating evidence suggests that reticulocytes (RETs) in the peripheral blood of rats may represent a suitable cell population for use in the micronucleus…”
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Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Groups 1, 2A and 2B): The summary report of the 6th collaborative study by CSGMT/JEMS·MMS
Published in Mutation research. Genetic toxicology and environmental mutagenesis (28-02-1997)“…To assess the correlation between micronucleus induction and human carcinogenicity, the rodent micronucleus assay was performed on known and potential human…”
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Performance of flow cytometric analysis for the micronucleus assay—a reconstruction model using serial dilutions of malaria-infected cells with normal mouse peripheral blood
Published in Mutagenesis (01-01-2006)“…To confirm the performance and statistical power of a flow cytometric method for scoring micronucleated erythrocytes, reconstruction experiments were…”
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Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report
Published in Mutation research (03-02-2007)“…At the Plymouth Third International Workshop on Genotoxicity Testing in June 2002, a new expert group started a working process to provide guidance on a common…”
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Journal Article Conference Proceeding -
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An automated new technique for scoring the rodent micronucleus assay: computerized image analysis of acridine orange supravitally stained peripheral blood cells
Published in Mutation research (03-08-1998)“…We developed an automated image analysis system to obtain objective data for the rodent peripheral blood micronucleus assay with acridine orange (AO)…”
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In vivo erythrocyte micronucleus assay
Published in Mutation research. Genetic toxicology and environmental mutagenesis (03-02-2007)“…The in vivo micronucleus assay working group of the International Workshop on Genotoxicity Testing (IWGT) discussed new aspects in the in vivo micronucleus…”
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Detection of genotoxicity of polluted sea water using shellfish and the alkaline single-cell gel electrophoresis (SCE) assay: a preliminary study
Published in Mutation research (18-09-1997)“…We exposed two species of shellfish, Patunopecten yessoensis and Tapes japonica, for 4 h to artificial sea water in which N-methyl- N′-nitro-…”
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A cell line from teleost fish: Establishment and cytogenetical characterization of the cells
Published in Idengaku zasshi (1976)“…A procedure for the establishment of a cell line from the Gin-buna, Carassius auratus langsdorfii, is described. The cells of this line are characterized by…”
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Evaluation of the rat micronucleus test with bone marrow and peripheral blood: Summary of the 9th collaborative study by CSGMT/JEMS·MMS
Published in Environmental and molecular mutagenesis (1998)“…The mouse has traditionally been used for the micronucleus test, with bone marrow the usual target organ. The aim of the 9th collaborative study by CSGMT was…”
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A Cytological Evidence for Gynogenetic Development of the Ginbuna (Carassius auratus langsdorfii)
Published in Proceedings of the Japan Academy, Series B (1977)Get full text
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Micronucleus test with colchicine given by intraperitoneal injection and oral gavage
Published in Mutation research (01-08-1989)“…The effects of micronucleus induction in mouse bone marrow cells by intraperitoneal injection (i.p.) and oral administration (p.o.) were studied with the…”
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