Search Results - "ASAMOTO, M"

5‐Aza‐2′‐deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up‐regulation of the connexin 32 gene by Hagiwara, H, Sato, H, Ohde, Y, Takano, Y, Seki, T, Ariga, T, Hokaiwado, N, Asamoto, M, Shirai, T, Nagashima, Y, Yano, T

“…Background and purpose: The connexin (Cx) 32 gene, a member of the gap junction gene family, acts as a tumour suppressor gene in human renal cell carcinoma…”
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Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells by Ito, Aya, Asamoto, Makoto, Hokaiwado, Naomi, Takahashi, Satoru, Shirai, Tomoyuki

“…In the present study, Tbx3, a member of the T-box family of transcription factors, was identified as an up-regulated gene by mRNA differential display in the…”
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Differential effect of subcellular localization of communication impairing gap junction protein connexin43 on tumor cell growth in vivo by KRUTOVSKIKH, V. A, TROYANOVSKY, S. M, PICCOLI, C, TSUDA, H, ASAMOTO, M, YAMASAKI, H

“…There is a large body of evidence suggesting the connexin gap junction proteins appear to act as tumor suppressors, and their tumor inhibitory effect is…”
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Transgenic rats carrying human c-Ha-ras proto-oncogenes are highly susceptible to N-methyl-N-nitrosourea mammary carcinogenesis by Asamoto, Makoto, Ochiya, Takahiro, Toriyama-Baba, Hiroyasu, Ota, Tomonori, Sekiya, Takao, Terada, Masaaki, Tsuda, Hiroyuki

“…A rat line carrying three copies of the human c-Ha-ras proto-oncogene, including its own promoter region, was established and designated Hras128. Expression of…”
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Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis by Imaida, K., Tamano, S., Kato, K., Ikeda, Y., Asamoto, M., Takahashi, S., Nir, Z., Murakoshi, M., Nishino, H., Shirai, T.

“…The chemopreventive efficacy of lycopene and curcumin with regard to prostate carcinogenesis was investigated using 3,2′-dimethyl-4-aminobiphenol (DMAB)- and…”
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Inhibitory effects of docosahexaenoic acid on colon carcinoma 26 metastasis to the lung by LIGO, M, NAKAGAWA, T, ISHIKAWA, C, IWAHORI, Y, ASAMOTO, M, YAZAWA, K, ARAKI, E, TSUDA, H

“…Unsaturated fatty acids, including n-3 polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acid (C22:6, DHA) and eicosapentaenoic acid (C20:5, EPA),…”
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Regulation of Connexin 43-Mediated Gap Junctional Intercellular Communication by CA2+in Mouse Epidermal Cells Is Controlled by E-Cadherin by Wim M. F. Jongen, Fitzgerald, D. James, Asamoto, Makoto, Piccoli, Colette, Slaga, Thomas J., Gros, Daniel, Takeichi, Masatoshi, Yamasaki, Hiroshi

“…Gap junctional intercellular communication (GJIC) of cultured mouse epidermal cells is mediated by a gap junction protein, connexin 43, and is dependent on the…”
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Inhibition of intrinsic gap-junction intercellular communication and enhancement of tumorigenicity of the rat bladder carcinoma cell line BC31 by a dominant-negative connexin 43 mutant by Krutovskikh, Vladimir A., Yamasaki, Hiroshi, Tsuda, Hiroyuki, Asamoto, Makoto

“…The tumor‐suppressive property of the connexin gap‐junction proteins was postulated from the fact that their function of cell coupling is impaired in most…”
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Reversibility of proliferative lesions and induction of non-papillary tumors in rat urinary bladder treated with phenylethyl isothiocyanate by Sugiura, Satoshi, Ogawa, Kumiko, Hirose, Masao, Takeshita, Fumitaka, Asamoto, Makoto, Shirai, Tomoyuki

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Organ dependent enhancement of rat 3,2′-dimethyl-4-aminobiphenyl (DMAB) carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): positive effects on the intestine but not the prostate by Imaida, Katsumi, Sano, Masashi, Tamano, Seiko, Asamoto, Makoto, Ogawa, Kumiko, Futakuchi, Mitsuru, Shirai, Tomoyuki

“…In order to evaluate tumor enhancing effects of the heterocyclic carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), doses of 100 and 300…”
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Suppressive effects of antiandrogens, finasteride and flutamide on development of prostatic lesions in a transgenic rat model by Cho, Y-M, Takahashi, S, Asamoto, M, Suzuki, S, Tang, M, Shirai, T

“…Transgenic (TG) rats bearing a probasin promoter/simian virus 40 T antigen (SV40 Tag) construct were treated with antiandrogens to examine their ability to…”
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Gap Junction Dysfunction Reduces Acetaminophen Hepatotoxicity with Impact on Apoptotic Signaling and Connexin 43 Protein Induction in Rat by Naiki-Ito, Aya, Asamoto, Makoto, Naiki, Taku, Ogawa, Kumiko, Takahashi, Satoru, Sato, Shinya, Shirai, Tomoyuki

“…Acetaminophen (APAP) is a widely used antipyretic and analgesic agent. However, overdosing and sometimes even a recommended dose can lead to serious and…”
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Mutations and expression of the p53 gene in rat bladder carcinomas and cell lines by Asamoto, M, Mann, A M, Macatee, T L, Cohen, S M

“…Abnormalities of the p53 gene are frequently observed in human tumors, including urinary bladder carcinoma, suggesting that p53 plays an important role in…”
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Inhibition of rat hepatic glutathione S-transferase placental form positive foci development by concomitant administration of antioxidants to carcinogen-treated rats by Asamoto, M, Shichino, Y, Tsuda, H, Ito, N

“…Inhibition potential of concomitant butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), catechol or sodium ascorbate (Na-AsA) administration on…”
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Modification by sodium L-ascorbate, butylated hydroxytoluene, phenobarbital and pepleomycin of lesion development in a wide-spectrum initiation rat model by Thamavit, W, Fukushima, S, Kurata, Y, Asamoto, M, Ito, N

“…Rats were treated for 1 week each with 0.05% N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN), 0.2% N-bis(2-hydroxypropyl)-nitrosamine (DHPN) and 0.2%…”
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Glutathione S-transferase Pi mediates proliferation of androgen-independent prostate cancer cells by Hokaiwado, Naomi, Takeshita, Fumitaka, Naiki-Ito, Aya, Asamoto, Makoto, Ochiya, Takahiro, Shirai, Tomoyuki

“…Prostate cancers generally acquire an androgen-independent growth capacity with progression, resulting in resistance to antiandrogen therapy. Therefore,…”
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Effect of pulsed radiofrequency treatment for postherpetic itch: 14AP2-11 by Sekiyama, H., Asamoto, M., Sato, K., Kogure, T., Sumitani, M., Yamada, Y.

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Regression of simple hyperplasia and papillomas and persistence of basal cell hyperplasia in the forestomach of F344 rats treated with butylated hydroxyanisole by MASUI, T, ASAMOTO, M, HIROSE, M, FUKUSHIMA, S, ITO, N

“…The reversibility of forestomach lesions induced in rats by butylated hydroxyanisole (BHA) was examined. F344 rats were given a 2% BHA diet for 24, 48, or 72…”
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Species differences in sodium o-phenylphenate induction of urinary bladder lesions by Hasegawa, R, Takahashi, S, Asamoto, M, Shirai, T, Fukushima, S

“…The effects of sodium o-phenylphenate (Na-OPP) treatment on urinary bladder epithelium were examined in male F344 rats, B6C3F1 mice, Syrian golden hamsters and…”
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Specific differences in gene expression profile revealed by cDNA microarray analysis of glutathione S-transferase placental form (GST-P) immunohistochemically positive rat liver foci and surrounding tissue by Suzuki, Shugo, Asamoto, Makoto, Tsujimura, Kazunari, Shirai, Tomoyuki

“…Glutathione S-transferase placental form (GST-P), one of the glutathione S-transferases family of detoxification enzymes, is a very useful marker of rat liver…”
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