Search Results - "ARYAL, PRAMOD"

Baicalein induces autophagic cell death through AMPK/ULK1 activation and downregulation of mTORC1 complex components in human cancer cells by Aryal, Pramod, Kim, Kijoong, Park, Pil‐Hoon, Ham, Seongho, Cho, Junghee, Song, Kyung

“…Baicalein, a flavonoid and aglycon hydrolyzed from baicalin, has anticancer properties in several human carcinomas, but its molecular mechanisms of action…”
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Synthesis and Self-Assembling Properties of Carbohydrate- and Diarylethene-Based Photoswitchable Molecular Gelators by Aryal, Pramod, Morris, Joedian, Adhikari, Surya B, Bietsch, Jonathan, Wang, Guijun

“…Carbohydrate-based low-molecular-weight gelators are interesting new materials with many potential applications. These compounds can be designed to include…”
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Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins by Devkota, Shankar Raj, Aryal, Pramod, Pokhrel, Rina, Jiao, Wanting, Perry, Andrew, Panjikar, Santosh, Payne, Richard J., Wilce, Matthew C. J., Bhusal, Ram Prasad, Stone, Martin J.

“…Chemokines are key regulators of leukocyte trafficking and attractive targets for anti-inflammatory therapy. Evasins are chemokine-binding proteins from tick…”
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Prospects of Indole derivatives as methyl transfer inhibitors: antimicrobial resistance managers by Tha, Suprim, Shakya, Sapana, Malla, Rajani, Aryal, Pramod

“…It is prudent that novel classes of antibiotics be urgently developed to manage the WHO prioritized multi-drug resistant (MDR) pathogens posing an…”
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Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity by Chhetry, Alisha Karki, Dhakal, Subhila, Chaudhary, Lalita, Karki, Khimdhoj, Khadka, Ram Bahadur, Chaudhary, Gautam Prasad, Bastola, Tonking, Poudel, Amrit, Aryal, Pramod, Pandey, Jitendra

“…This study was aimed to determine the antibacterial activity of root bark, leaves, and pericarp extract of Diploknema butyracea and to evaluate the prospective…”
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Anti-Inflammatory Activity of Artemisia vulgaris Leaves, Originating from Three Different Altitudes of Nepal by Pandey, Jitendra, Bhusal, Sushma, Nepali, Laxman, Khatri, Maya, Ramdam, Rasmita, Barakoti, Himal, Giri, Paras Mani, Pant, Dhakaraj, Aryal, Pramod, Rokaya, Rabindra Kumar, Bhandari, Ravin

“…This study aimed to evaluate and compare the in vivo chronic anti-inflammatory efficacy, from the ethyl acetate and ethanolic extracts of Artemisia vulgaris…”
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Physicochemical Evaluation of Diploknema butyracea Seed Extract and Formulation of Ketoconazole Ointment by Using the Fat as a Base by Pandey, Jitendra, Khanal, Bimal, Bhandari, Jhabilal, Bashyal, Rishav, Pandey, Asmita, Mikrani, Asgar Ali, Aryal, Pramod, Bhandari, Ravin

“…The fat obtained from the ripened seeds of Diploknema butyracea is widely used as a vegetable oil in rural areas of Nepal. This study was aimed for the…”
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Evaluation of Phytochemical, Antioxidant, and Memory-Enhancing Activity of Garuga pinnata Roxb. Bark and Bryophyllum pinnatum (Lam) Oken. Leaves by Bhandari, Ravin, Gyawali, Sabina, Aryal, Nisha, Gaire, Devika, Paudyal, Kalpana, Panta, Abaru, Panth, Pooja, Joshi, Dirgha Raj, Rokaya, Rabindra Kumar, Aryal, Pramod, Pandey, Jitendra

“…Garugapinnata Roxb. (Burseraceae) is a medium-sized tree widely available all over the tropical regions of Asia. Bryophyllum pinnatum (Lam) Oken…”
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Antipyretic, Antinociceptive, and Anti-Inflammatory Activities from Pogostemon benghalensis Leaf Extract in Experimental Wister Rats by Aryal, Sushant, Adhikari, Balkrishna, Panthi, Kasmira, Aryal, Pramod, Mallik, Shyam Kumar, Bhusal, Ram Prasad, Salehi, Bahare, Setzer, William N, Sharifi-Rad, Javad, Koirala, Niranjan

“…leaves have traditionally been utilized for relieving body aches, headaches and fever. Based on its uses, the present study was designed to investigate the…”
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Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase by Oda, Yoshimitsu, Aryal, Pramod, Terashita, Takao, Gillam, Elizabeth M.J, Guengerich, F.Peter, Shimada, Tsutomu

“…We investigated roles of different forms of cytochrome P450 (P450 or CYP) in the metabolic activation of heterocyclic amines (HCAs) and other procarcinogens to…”
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Swapping N-terminal regions among tick evasins reveals cooperative interactions influencing chemokine binding and selectivity by Aryal, Pramod, Devkota, Shankar Raj, Jeevarajah, Devadharshini, Law, Ruby, Payne, Richard J., Bhusal, Ram Prasad, Stone, Martin J.

“…Class A tick evasins are natural chemokine-binding proteins that block the signaling of multiple chemokines from the CC subfamily through their cognate…”
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Structural basis of chemokine recognition by the class A3 tick evasin EVA‐ACA1001 by Devkota, Shankar Raj, Aryal, Pramod, Wilce, Matthew C. J., Payne, Richard J., Stone, Martin J., Bhusal, Ram Prasad

“…Ticks produce chemokine‐binding proteins, known as evasins, in their saliva to subvert the host's immune response. Evasins bind to chemokines and thereby…”
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Correction to: Transcriptional suppression of androgen receptor by 18β-glycyrrhetinic acid in LNCaP human prostate cancer cells by Sun, You, Aryal, Pramod, Jiang, Mingyue, Wu, Shuang, Park, Pil-Hoon, Song, Kyung

“…The authors regret to inform that authors Pramod Aryal and Shuang Wu were inadvertently omitted from authorship of the manuscript above at the time of original…”
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Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases by Bhusal, Ram Prasad, Aryal, Pramod, Devkota, Shankar Raj, Pokhrel, Rina, Gunzburg, Menachem J, Foster, Simon R, Lim, Herman D, Payne, Richard J, Wilce, Matthew C J, Stone, Martin J

“…As natural chemokine inhibitors, evasin proteins produced in tick saliva are potential therapeutic agents for numerous inflammatory diseases. Engineering…”
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Synthesis of Bis-Thioacid Derivatives of Diarylethene and Their Photochromic Properties by Aryal, Pramod, Bietsch, Jonathan, Grandhi, Gowri Sankar, Chen, Richard, Adhikari, Surya B., Sarabamoun, Ephraiem S., Choi, Joshua J., Wang, Guijun

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PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIDIARRHOEAL ACTIVITY OF BUNIUM BULBOCASTANUM SEEDS EXTRACT IN EXPERIMENTAL WISTAR RATS by KHANAL, PITAMBAR, PAUDEL, NABINA, ARYAL, SUSHANT, ARYAL, PRAMOD

“…Objective: The main objective of this study was to evaluate the antidiarrheal activity of Bunim bulbocastanum seeds extracts, to exploit the medicinal use of…”
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Photoluminescence switching in quantum dots connected with fluorinated and hydrogenated photochromic molecules by Sarabamoun, Ephraiem S, Bietsch, Jonathan M, Aryal, Pramod, Reid, Amelia G, Curran, Maurice, Johnson, Grayson, Tsai, Esther H. R, Machan, Charles W, Wang, Guijun, Choi, Joshua J

“…We investigate switching of photoluminescence (PL) from PbS quantum dots (QDs) crosslinked with two different types of photochromic diarylethene molecules,…”
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Physicochemical evaluation of Prinsepia utilis seed oil (PUSO) and its utilization as a base in pharmaceutical soap formulation by Pandey, Jitendra, Acharya, Srijana, Bagale, Rakshya, Gupta, Akriti, Chaudhary, Pooja, Rokaya, Bikash, Manju, K.C., Aryal, Pramod, Devkota, Hari Prasad

“…This study aims to evaluate the standard physicochemical parameters, such as iodine value, acid value, saponification value, ester value, refractive index,…”
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Valorization of Cheese Whey through Bioethanol Production and Probiotic Drink Development: A Sustainable Approach for Organic Waste Management by Maidali, Devraj, Magar, Sabina Thapa, Ghimire, Sita, Pun, Manju, Pun, Shreejana, Chataut, Guheswari, Maharjan, Suja, Subedi, Samiran

“…Cheese whey, a significant byproduct of the dairy industry, poses a substantial environmental challenge due to its organic pollutant load and large size…”
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Phytochemical screening, antibacterial-guided fractionation, and thin-layer chromatographic pattern of the extract obtained from Diploknema butyracea by Tiwari, Supriya, Nepal, Samjhana, Sigdel, Shraddha, Bhattarai, Sarju, Rokaya, Rabindra, Pandey, Jitendra, Khadka, Ram, Aryal, Pramod, Bhandari, Ravin

“…Objective: Diploknema butyracea (family: Sapotaceae), commonly known as the Indian butter tree or Chyuri, is habitat to Nepal and distributed from Garhwal to…”
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