Vitreoretinal alterations following laser in situ keratomileusis: clinical and experimental studies

The presence of vitreoretinal changes following laser in situ keratomileusis in myopia is evaluated. Clinically, 50 patients (100 eyes) with marked anisometropic myopia, 50 low-myopic eyes (<4.00 D) and 50 high-myopic eyes (>7.00 D) were prospectively evaluated pre- and postoperatively for the...

Full description

Saved in:

Bibliographic Details
Published in:	Graefe's archive for clinical and experimental ophthalmology Vol. 239; no. 6; pp. 416 - 423
Main Authors:	LUNA, José D, ARTAL, Maria N, REVIGLIO, Victor E, PELIZZARI, Mario, DIAZ, Hugo, JUAREZ, Claudio P
Format:	Conference Proceeding Journal Article
Language:	English
Published:	Berlin Springer 01-07-2001 Springer Nature B.V
Subjects:	Adult Animals Biological and medical sciences Choroid - blood supply Cornea - surgery Electroretinography Female Fluorescein Angiography Humans Keratomileusis, Laser In Situ - adverse effects Male Medical sciences Myopia - surgery Ophthalmology Prospective Studies Retinal Diseases - diagnostic imaging Retinal Diseases - etiology Retinal Diseases - pathology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the eye and orbit Swine Ultrasonography Vitreous Detachment - diagnostic imaging Vitreous Detachment - etiology Vitreous Detachment - pathology Human Postoperative Retinopathy Iatrogenic Keratomileusis In situ Alteration Experimental study Pig Vitreous body disease Photocoagulation Eye disease Vertebrata Mammalia Surgery Animal Laser Complication Vitreoretinal Artiodactyla Ungulata
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The presence of vitreoretinal changes following laser in situ keratomileusis in myopia is evaluated. Clinically, 50 patients (100 eyes) with marked anisometropic myopia, 50 low-myopic eyes (<4.00 D) and 50 high-myopic eyes (>7.00 D) were prospectively evaluated pre- and postoperatively for the presence of newly recognized entoptic phenomena (vitreous floaters, light flashes, or both), and for vitreoretinal changes using indirect depressed fundus examination, a +90 D preset lens, Goldman three-mirror contact lens, and kinetic ultrasound (KU) before and after bilateral LASIK. Patients with previous partial or total posterior vitreous cortex detachment (PVD) were excluded. Experimentally, groups of adult pigs underwent KU, retinal fluorescein angiography (FA), and electroretinography (ERG) before and after applying the microkeratome suction ring for 30 s. Clinically, 8% (4 eyes) had positive perception of postoperative vitreous floaters in the low myopia group, and 32% (16 eyes) in the high myopia group. Postoperative light flashes were noted only in the high myopia group, in 12% of cases. Partial or total posterior vitreous cortex detachment was detected by biomicroscopy in 2% (1 eye) of the low and in 10% (5 eyes) of the high myopia group and by KU in 4% (2 eyes) of the low and in 24% (12 eyes) of the high myopia group. Experimentally, 2 pig eyes out of 12 developed partial PVD by KU, immediately after microkeratome suction ring application. All pig eyes showed significantly diminished ERG amplitudes during and immediately after suction ring application. No FA changes or delays in retinal circulation time were noted during or immediately after removal of the suction ring. Vitreoretinal alterations after LASIK were demonstrated clinically mainly by KU in high myopes. Experimentally, PVD were also demonstrated. Diminished ERG recordings with normal retinal circulation following suction ring application may suggest some transient choroidal circulation abnormalities.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0721-832X 1435-702X
DOI:	10.1007/s004170100295