Search Results - "ARRIBAS, J"

COVID-19 face masks: A new source of human and environmental exposure to organophosphate esters by Fernández-Arribas, J., Moreno, T., Bartrolí, R., Eljarrat, E.

“…[Display omitted] •OPEs were detected for the first time in face masks at levels up to 28 µg/mask.•KN95 masks presented the highest OPE values.•A 10% of OPE…”
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Comprehensive risk assessment of the inhalation of plasticizers from the use of face masks by Callejas-Martos, S., Fernández-Arribas, J., Eljarrat, E.

“…[Display omitted] •The overall plasticizer concentration was similar in all four face mask types.•Different face mask types showed varying plasticizer…”
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A predictive hybrid reduced order model based on proper orthogonal decomposition combined with deep learning architectures by Abadía-Heredia, R., López-Martín, M., Carro, B., Arribas, J.I., Pérez, J.M., Le Clainche, S.

“…Solving computational fluid dynamics problems requires using large computational resources. The computational time and memory requirements to solve realistic…”
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2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0 by Ryom, L, Cotter, A, De Miguel, R, Béguelin, C, Podlekareva, D, Arribas, JR, Marzolini, C, Mallon, PGM, Rauch, A, Kirk, O, Molina, JM, Guaraldi, G, Winston, A, Bhagani, S, Cinque, P, Kowalska, JD, Collins, S, Battegay, M, De Miguel Buckley, Rosa, d'Arminio Monforte, Antonella, Bracchi, Margherita, Dedes, Nikos, Horban, Andrzej, Katlama, Christine, Latysheva, Inga, Lundgren, Jens D., McCormack, Sheena, Mussini, Cristina, Pozniak, Anton, Pulido, Federico, Raffi, François, Reiss, Peter, Stellbrink, Hans‐Jürgen, Vasylyev, Marta, Gibbons, Sara, Livio, Françoise, Behrens, Georg, Bower, Mark, Compston, Juliet, De Wit, Stéphane, Fabbri, Leonardo M., Fux, Christoph A., Gisslen, Magnus, Lundgren, Jens D., Martínez, Esteban, Miro, José M., Negredo, Eugenia, Poulter, Neil, Reiss, Peter, Sebastiani, Giada, Berenguer, Juan, Boesecke, Christoph, Bruno, Raffaele, Konov, Svilen, Lacombe, Karine, Mauss, Stefan, Mendão, Luís, Peters, Lars, Puoti, Massimo, Rockstroh, Jürgen K., Ambrosioni, Juan, De Castro, Nathalie, Fätkenheuer, Gerd, Furrer, Hansjakob, Miro, José M., Oprea, Cristiana, Pozniak, Anton, Volny‐Anne, Alain, Rockstroh, Jürgen K., Sullivan, Ann, Martínez, Esteban, Mulcahy, Fiona, d'Arminio Monforte, Antonella, Behrens, Georg, Katlama, Christine, Lundgren, Jens D., Mussini, Cristina, Oprea, Cristiana, Pozniak, Anton, Reiss, Peter, Wensing, Annemarie

“…Background The European AIDS Clinical Society (EACS) Guidelines cover key aspects of HIV management with major updates every two years. Guideline highlights…”
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PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer by Serra, V, Scaltriti, M, Prudkin, L, Eichhorn, P J A, Ibrahim, Y H, Chandarlapaty, S, Markman, B, Rodriguez, O, Guzman, M, Rodriguez, S, Gili, M, Russillo, M, Parra, J L, Singh, S, Arribas, J, Rosen, N, Baselga, J

“…There is a strong rationale to therapeutically target the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway…”
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Organophosphate esters in airborne particles from subway stations by Olivero-Verbel, R., Moreno, T., Fernández-Arribas, J., Reche, C., Minguillón, M.C., Martins, V., Querol, X., Johnson-Restrepo, B., Eljarrat, E.

“…For the first time, the concentrations of 19 organophosphate esters (OPEs) were measured in airborne fine particulate matter (PM2.5) from subway stations in…”
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Minimal Clinically Important Difference in Quality of Life for Patients With Low Back Pain by Díaz-Arribas, María J., Fernández-Serrano, Mónica, Royuela, Ana, Kovacs, Francisco M., Gallego-Izquierdo, Tomás, Ramos-Sánchez, Mabel, Llorca-Palomera, Rosa, Pardo-Hervás, Pedro, Martín-Pariente, Oscar S.

“…STUDY DESIGN.Multicenter, prospective, cohort study. OBJECTIVE.To estimate the Minimal Clinically Important Difference (MCID) for the physical (PCS) and mental…”
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Effectiveness of the Bobath concept in the treatment of stroke: a systematic review by Díaz-Arribas, María J., Martín-Casas, Patricia, Cano-de-la-Cuerda, Roberto, Plaza-Manzano, Gustavo

“…Purpose: To evaluate the effectiveness of the Bobath concept in sensorimotor rehabilitation after stroke. Materials and methods: A systematic literature review…”
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Re-examining class-I presentation and the DRiP hypothesis by Rock, Kenneth L, Farfán-Arribas, Diego J, Colbert, Jeff D, Goldberg, Alfred L

“…Highlights • Class I-presented peptides may derive from normal functional protein and DRiPs. • The favored model posits that most peptides are derived from…”
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Kinetics and toxicity of nanoplastics in ex vivo exposed human whole blood as a model to understand their impact on human health by Arribas Arranz, J., Villacorta, A., Rubio, L., García-Rodríguez, A., Sánchez, G., Llorca, M., Farre, M., Ferrer, J.F., Marcos, R., Hernández, A.

“…The ubiquitous presence of nanoplastics (NPLs) in the environment is considered of great health concern. Due to their size, NPLs can cross both the intestinal…”
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Proteases in MHC Class I Presentation and Cross-Presentation by Rock, Kenneth L, Farfan-Arribas, Diego J, Shen, Lianjun

“…Cells that have mutated their genes or are virally infected are a potential threat to a host. Consequently, the immune system has evolved mechanisms for CD8 T…”
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Novel insights into the genetics and epigenetics of MALT lymphoma unveiled by next generation sequencing analyses by Cascione, Luciano, Rinaldi, Andrea, Bruscaggin, Alessio, Tarantelli, Chiara, Arribas, Alberto J, Kwee, Ivo, Pecciarini, Lorenza, Mensah, Afua A, Spina, Valeria, Chung, Elaine Y L, di Bergamo, Lodovico Terzi, Dirnhofer, Stephan, Tzankov, Alexandar, Miranda, Roberto N, Young, Ken H, Traverse-Glehen, Alexandra, Gaidano, Gianluca, Swerdlow, Steven H, Gascoyne, Randy, Rabadan, Raul, Ponzoni, Maurilio, Bhagat, Govind, Rossi, Davide, Zucca, Emanuele, Bertoni, Francesco

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Efficacy of protease inhibitor monotherapy vs. triple therapy: meta‐analysis of data from 2303 patients in 13 randomized trials by Arribas, JR, Girard, P‐M, Paton, N, Winston, A, Marcelin, A‐G, Elbirt, D, Hill, A, Hadacek, MB

“…Objectives The aim of this analysis was to review the evidence and update a meta‐analysis evaluating the efficacy and safety results from randomized controlled…”
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The MONET trial: week 144 analysis of the efficacy of darunavir/ritonavir (DRV/r) monotherapy versus DRV/r plus two nucleoside reverse transcriptase inhibitors, for patients with viral load < 50 HIV‐1 RNA copies/mL at baseline by Arribas, JR, Clumeck, N, Nelson, M, Hill, A, Delft, Y, Moecklinghoff, C

“…Background In the MONotherapy in Europe with Tmc114 (MONET) trial, darunavir/ritonavir (DRV/r) monotherapy showed noninferior efficacy vs. two nucleoside…”
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Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity by Scaltriti, M, Verma, C, Guzman, M, Jimenez, J, Parra, J L, Pedersen, K, Smith, D J, Landolfi, S, Ramon y Cajal, S, Arribas, J, Baselga, J

“…Lapatinib is a human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitor (TKI) that has clinical activity in HER2-amplified breast cancer. In…”
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Expression of p95HER2, a Truncated Form of the HER2 Receptor, and Response to Anti-HER2 Therapies in Breast Cancer by Scaltriti, Maurizio, Rojo, Federico, Ocaña, Alberto, Anido, Judit, Guzman, Marta, Cortes, Javier, Di Cosimo, Serena, Matias-Guiu, Xavier, Ramon y Cajal, Santiago, Arribas, Joaquin, Baselga, José

“…Background Women with HER2–overexpressing breast cancers have poor prognosis, and many are resistant to the HER2 monoclonal antibody trastuzumab. A subgroup of…”
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Highlights of the 2017 European AIDS Clinical Society (EACS) Guidelines for the treatment of adult HIV‐positive persons version 9.0 by Ryom, L, Boesecke, C, Bracchi, M, Ambrosioni, J, Pozniak, A, Arribas, J, Behrens, G, Mallon, PGM, Puoti, M, Rauch, A, Miro, JM, Kirk, O, Marzolini, C, Lundgren, JD, Battegay, M, d'Arminio Monforte, Antonella, Clumeck, Nathan, Dedes, Nikos, Gatell, José M., Horban, Andrzej, Katlama, Christine, McCormack, Sheena, Molina, Jean‐Michel, Mussini, Cristina, Raffi, François, Reiss, Peter, Stellbrink, Hans‐Jürgen, Bower, Mark, Cinque, Paola, Collins, Simon, Compston, Juliet, De Wit, Stéphane, Fabbri, Leonardo M., Fux, Christoph A., Guaraldi, Giovanni, Martínez, Esteban, Papapoulos, Socrates, Pasquier, Renaud, Poulter, Neil, Williams, Ian, Winston, Alan, Berenguer, Juan, Bhagani, Sanjay, Bruno, Raffaele, Konov, Svilen, Lacombe, Karine, Mauss, Stefan, Mendão, Luís, Peters, Lars, Rockstroh, Jürgen K., Fätkenheuer, Gerd, Furrer, Hansjakob, Mocroft, Amanda, Morlat, Philippe, Volny‐Anne, Alain

“…Background The European AIDS Clinical Society (EACS) Guidelines have since 2005 provided multidisciplinary recommendations for the care of HIV‐positive persons…”
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A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers by Spriano, Filippo, Sartori, Giulio, Sgrignani, Jacopo, Barnabei, Laura, Arribas, Alberto J, Guala, Matilde, Del Amor, Ana Maria Carrasco, Tomasso, Meagan R, Tarantelli, Chiara, Cascione, Luciano, Golino, Gaetanina, Riveiro, Maria E, Bortolozzi, Roberta, Lupia, Antonio, Paduano, Francesco, Huguet, Samuel, Rezai, Keyvan, Rinaldi, Andrea, Margheriti, Francesco, Ventura, Pedro, Guarda, Greta, Costa, Giosuè, Rocca, Roberta, Furlan, Alberto, Verdonk, Luuk M, Innocenti, Paolo, Martin, Nathaniel I, Viola, Giampietro, Driessen, Christoph, Zucca, Emanuele, Stathis, Anastasios, Gahtory, Digvijay, Van den Nieuwboer, Maurits, Bornhauser, Beat, Alcaro, Stefano, Trapasso, Francesco, Cristobal, Susana, Padrick, Shae B, Pazzi, Natalina, Cavalli, Franco, Cavalli, Andrea, Gaudio, Eugenio, Bertoni, Francesco

“…Hematological cancers are among the most common cancers in adults and children. Despite significant improvements in therapies, many patients still succumb to…”
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The Bruton tyrosine kinase inhibitor zanubrutinib (BGB-3111) demonstrated synergies with other anti-lymphoma targeted agents by Tarantelli, Chiara, Zhang, Lu, Curti, Elisabetta, Gaudio, Eugenio, Spriano, Filippo, Priebe, Valdemar, Cascione, Luciano, Arribas, Alberto J, Zucca, Emanuele, Rossi, Davide, Stathis, Anastasios, Bertoni, Francesco

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LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells by Cebrià-Costa, J. P., Pascual-Reguant, L., Gonzalez-Perez, A., Serra-Bardenys, G., Querol, J., Cosín, M., Verde, G., Cigliano, R. A., Sanseverino, W., Segura-Bayona, S., Iturbide, A., Andreu, D., Nuciforo, P., Bernado-Morales, C., Rodilla, V., Arribas, J., Yelamos, J., de Herreros, A. Garcia, Stracker, T. H., Peiró, S.

“…Oxidation of H3 at lysine 4 (H3K4ox) by lysyl oxidase-like 2 (LOXL2) generates an H3 modification with an unknown physiological function. We find that LOXL2…”
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