Search Results - "ARRA, CLAUDIO"

Microbiota effects on cancer: from risks to therapies by Rea, Domenica, Coppola, Giovanni, Palma, Giuseppe, Barbieri, Antonio, Luciano, Antonio, Del Prete, Paola, Rossetti, Sabrina, Berretta, Massimiliano, Facchini, Gaetano, Perdonà, Sisto, Turco, Maria Caterina, Arra, Claudio

“…Gut microbiota, a group of 10 bacteria, eukaryotes and virus living in gastrointestinal tract, is crucial for many physiological processes in particular plays…”
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Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents by Giudice, Aldo, Arra, Claudio, Turco, Maria C

“…Human exposures to environmental toxicants have been associated with etiology of many diseases including inflammation, cancer, and cardiovascular and…”
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A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo by Mele, Luigi, Paino, Francesca, Papaccio, Federica, Regad, Tarik, Boocock, David, Stiuso, Paola, Lombardi, Angela, Liccardo, Davide, Aquino, Gabriella, Barbieri, Antonio, Arra, Claudio, Coveney, Clare, La Noce, Marcella, Papaccio, Gianpaolo, Caraglia, Michele, Tirino, Virginia, Desiderio, Vincenzo

“…Pentose phosphate pathway (PPP) is a major glucose metabolism pathway, which has a fundamental role in cancer growth and metastasis. Even though PPP blockade…”
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Current shreds of evidence on the anticancer role of EGCG in triple negative breast cancer: an update of the current state of knowledge by Bimonte, Sabrina, Cascella, Marco, Barbieri, Antonio, Arra, Claudio, Cuomo, Arturo

“…Triple-Negative Breast Cancer (TNBC), represents a subtype of breast cancer in which the estrogens receptor (ER) negative, the progesterone receptor (PR)…”
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Triple negative breast cancer: looking for the missing link between biology and treatments by Palma, Giuseppe, Frasci, Giuseppe, Chirico, Andrea, Esposito, Emanuela, Siani, Claudio, Saturnino, Carmela, Arra, Claudio, Ciliberto, Gennaro, Giordano, Antonio, D'Aiuto, Massimiliano

“…The so called "Triple Negative Breast Cancer" (TNBC) represents approximately 15-20% of breast cancers. This acronym simply means that the tumour does not…”
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Targeting CXCR4 potentiates anti-PD-1 efficacy modifying the tumor microenvironment and inhibiting neoplastic PD-1 by D'Alterio, Crescenzo, Buoncervello, Maria, Ieranò, Caterina, Napolitano, Maria, Portella, Luigi, Rea, Giuseppina, Barbieri, Antonio, Luciano, Antonio, Scognamiglio, Giosuè, Tatangelo, Fabiana, Anniciello, Anna Maria, Monaco, Mario, Cavalcanti, Ernesta, Maiolino, Piera, Romagnoli, Giulia, Arra, Claudio, Botti, Gerardo, Gabriele, Lucia, Scala, Stefania

“…Inefficient T-cell access to the tumor microenvironment (TME) is among the causes of tumor immune-resistance. Previous evidence demonstrated that targeting…”
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Anticancer and Anti-Inflammatory Properties of Ganoderma lucidum Extract Effects on Melanoma and Triple-Negative Breast Cancer Treatment by Barbieri, Antonio, Quagliariello, Vincenzo, Del Vecchio, Vitale, Falco, Michela, Luciano, Antonio, Amruthraj, Nagoth Joseph, Nasti, Guglielmo, Ottaiano, Alessandro, Berretta, Massimiliano, Iaffaioli, Rosario Vincenzo, Arra, Claudio

“…Among the most important traditional medicinal fungi, has been used as a therapeutic agent for the treatment of numerous diseases, including cancer, in…”
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Morphine Promotes Tumor Angiogenesis and Increases Breast Cancer Progression by Izzo, Francesco, Cuomo, Arturo, Luciano, Antonio, Palma, Giuseppe, Rea, Domenica, Barbieri, Antonio, Bimonte, Sabrina, Arra, Claudio

“…Morphine is considered a highly potent analgesic agent used to relieve suffering of patients with cancer. Several in vitro and in vivo studies showed that…”
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Critical role of HMGA proteins in cancer cell chemoresistance by D’Angelo, Daniela, Mussnich, Paula, Arra, Claudio, Battista, Sabrina, Fusco, Alfredo

“…The high-mobility group A (HMGA) proteins are frequently overexpressed in human malignancies and correlate with the presence of metastases and reduced patient…”
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Publisher Correction: HMGA1-pseudogene7 transgenic mice develop B cell lymphomas by De Martino, Marco, De Biase, Davide, Forzati, Floriana, Credendino, Sara Carmela, Palma, Giuseppe, Barbieri, Antonio, Arra, Claudio, Paciello, Orlando, Gaudio, Eugenio, Ponzoni, Maurilio, De Vita, Gabriella, Chieffi, Paolo, Bertoni, Francesco, Fusco, Alfredo, Esposito, Francesco

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Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases by Portella, Luigi, Vitale, Rosamaria, De Luca, Stefania, D'Alterio, Crescenzo, Ieranò, Caterina, Napolitano, Maria, Riccio, Anna, Polimeno, Maria Neve, Monfregola, Luca, Barbieri, Antonio, Luciano, Antonio, Ciarmiello, Andrea, Arra, Claudio, Castello, Giuseppe, Amodeo, Pietro, Scala, Stefania

“…The CXCR4/CXCL12 axis plays a role in cancer metastases, stem cell mobilization and chemosensitization. Proof of concept for efficient CXCR4 inhibition has…”
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Dissecting the mechanisms and molecules underlying the potential carcinogenicity of red and processed meat in colorectal cancer (CRC): an overview on the current state of knowledge by Cascella, Marco, Bimonte, Sabrina, Barbieri, Antonio, Del Vecchio, Vitale, Caliendo, Domenico, Schiavone, Vincenzo, Fusco, Roberta, Granata, Vincenza, Arra, Claudio, Cuomo, Arturo

“…Meat is a crucial nutrient for human health since it represents a giant supply of proteins, minerals, and vitamins. On the opposite hand, the intake of red and…”
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HMGA1-pseudogene7 transgenic mice develop B cell lymphomas by De Martino, Marco, De Biase, Davide, Forzati, Floriana, Credendino, Sara Carmela, Palma, Giuseppe, Barbieri, Antonio, Arra, Claudio, Paciello, Orlando, Gaudio, Eugenio, Ponzoni, Maurilio, De Vita, Gabriella, Chieffi, Paolo, Bertoni, Francesco, Fusco, Alfredo, Esposito, Francesco

“…We have recently identified and characterized two pseudogenes ( HMGA1P6 and HMGA1P7 ) of the HMGA1 gene, which has a critical role in malignant cell…”
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Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients by Petrizzo, Annacarmen, Tagliamonte, Maria, Mauriello, Angela, Costa, Valerio, Aprile, Marianna, Esposito, Roberta, Caporale, Andrea, Luciano, Antonio, Arra, Claudio, Tornesello, Maria Lina, Buonaguro, Franco M, Buonaguro, Luigi

“…A novel prediction algorithm is needed for the identification of effective tumor associated mutated neoantigens. Only those with no homology to self wild type…”
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Dissecting the Potential Roles of Nigella sativa and Its Constituent Thymoquinone on the Prevention and on the Progression of Alzheimer's Disease by Cascella, Marco, Bimonte, Sabrina, Barbieri, Antonio, Del Vecchio, Vitale, Muzio, Maria Rosaria, Vitale, Andrea, Benincasa, Giulio, Ferriello, Anna Bella, Azzariti, Amalia, Arra, Claudio, Cuomo, Arturo

“…Several nutraceuticals have been investigated for preventing or retarding the progression of different neurodegenerative diseases, including Alzheimer's…”
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Polyinosinic-polycytidylic acid limits tumor outgrowth in a mouse model of metastatic lung cancer by Forte, Giovanni, Rega, Alessia, Morello, Silvana, Luciano, Antonio, Arra, Claudio, Pinto, Aldo, Sorrentino, Rosalinda

“…Polyinosinic-polycytidylic acid (poly I:C), a TLR3 ligand, is currently being tested in human clinical trials as an adjuvant to anti-cancer vaccines and in…”
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Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production by Riccio, Gennaro, Antonucci, Salvatore, Coppola, Carmela, D'Avino, Chiara, Piscopo, Giovanna, Fiore, Danilo, Maurea, Carlo, Russo, Michele, Rea, Domenica, Arra, Claudio, Condorelli, Gerolama, Di Lisa, Fabio, Tocchetti, Carlo G, De Lorenzo, Claudia, Maurea, Nicola

“…The ErbB2 blocker trastuzumab improves survival in oncologic patients, but can cause cardiotoxicity. The late Na+ current inhibitor ranolazine has been shown…”
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miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene by Forzati, Floriana, De Martino, Marco, Esposito, Francesco, Sepe, Romina, Pellecchia, Simona, Malapelle, Umberto, Pellino, Gianluca, Arra, Claudio, Fusco, Alfredo

“…Loss of CBX7 expression has been described in several malignant neoplasias, including human colon and thyroid carcinomas proposing CBX7 as a tumor suppressor…”
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Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas by Carriero, Maria Vincenza, Bifulco, Katia, Ingangi, Vincenzo, Costantini, Susan, Botti, Giovanni, Ragone, Concetta, Minopoli, Michele, Motti, Maria Letizia, Rea, Domenica, Scognamiglio, Giosuè, Botti, Gerardo, Arra, Claudio, Ciliberto, Gennaro, Pessi, Antonello

“…The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion…”
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Role of Nigella sativa and Its Constituent Thymoquinone on Chemotherapy-Induced Nephrotoxicity: Evidences from Experimental Animal Studies by Cascella, Marco, Palma, Giuseppe, Barbieri, Antonio, Bimonte, Sabrina, Amruthraj, Nagoth Joseph, Muzio, Maria Rosaria, Del Vecchio, Vitale, Rea, Domenica, Falco, Michela, Luciano, Antonio, Arra, Claudio, Cuomo, Arturo

“…Most chemotherapeutic drugs are known to cause nephrotoxicity. Therefore, new strategies have been considered to prevent chemotherapy-induced nephrotoxicity…”
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