Search Results - "ARNQVIST, H"
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Declining incidence of severe retinopathy and persisting decrease of nephropathy in an unselected population of Type 1 diabetes-the Linköping Diabetes Complications Study
Published in Diabetologia (01-07-2004)“…In a previous study conducted over the last decades we found a decreased incidence of nephropathy but unchanged incidence of severe retinopathy among patients…”
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Lower levels of plasma 25-hydroxyvitamin D among young adults at diagnosis of autoimmune type 1 diabetes compared with control subjects : results from the nationwide Diabetes Incidence Study in Sweden (DISS)
Published in Diabetologia (2006)“…Low plasma vitamin D concentrations may promote the development of type 1 diabetes. To test this hypothesis, we measured plasma 25-hydroxyvitamin D (25OHD) in…”
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Gender differences and temporal variation in the incidence of type 1 diabetes: results of 8012 cases in the nationwide Diabetes Incidence Study in Sweden 1983–2002
Published in Journal of internal medicine (2008)“… Objectives. To establish the gender difference amongst newly diagnosed type 1 diabetic patients aged 15–34 years, considering age at diagnosis, temporal…”
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4
Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-I
Published in Hormone and metabolic research (01-06-2008)“…The aim of the study was to investigate if the insulin analogue glargine, with an increased affinity for the IGF-I receptor (IGF-IR), affects the cell growth…”
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The risk for diabetic nephropathy is low in young adults in a 17-year follow-up from the Diabetes Incidence Study in Sweden (DISS). Older age and higher BMI at diabetes onset can be important risk factors
Published in Diabetes/metabolism research and reviews (01-02-2015)“…Aims The main objective of this study was to estimate the occurrence of diabetic nephropathy in a population‐based cohort of patients diagnosed with diabetes…”
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Proinsulin/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults
Published in Diabetic medicine (01-02-2011)“…Diabet. Med. 28, 156–161 (2011) Aims After initiation of treatment in Type 1 diabetes, a period with lower insulin requirement often follows, reflecting…”
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The role of IGF-system in vascular insulin resistance
Published in Hormone and metabolic research (01-09-2008)“…Insulin and IGF-I are closely related peptides, which interact by several mechanisms. In high supraphysiological concentrations (> or = 10 (-8) M), they…”
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Assessment of beta‐cell function in young patients with type 2 diabetes: arginine‐stimulated insulin secretion may reflect beta‐cell reserve
Published in Journal of internal medicine (01-01-2014)“…Objective Simple methods for the evaluation of dynamic β‐cell function in epidemiological and clinical studies of patients with type 2 diabetes (T2D) are…”
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Excess mortality in incident cases of diabetes mellitus aged 15 to 34 years at diagnosis : a population-based study (DISS) in Sweden
Published in Diabetologia (01-04-2006)“…The objective of the study was to analyse the mortality, survival and cause of death patterns in incident cases of diabetes in the 15-34-year age group that…”
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Common variants in the TCF7L2 gene help to differentiate autoimmune from non-autoimmune diabetes in young (15-34 years) but not in middle-aged (40-59 years) diabetic patients
Published in Diabetologia (2008)“…Aims/hypothesis Type 1 diabetes in children is characterised by autoimmune destruction of pancreatic beta cells and the presence of certain risk genotypes. In…”
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Expression and function of receptors for insulin-like growth factor-I and insulin in human coronary artery smooth muscle cells
Published in Diabetologia (01-10-2005)“…Hyperinsulinaemia and insulin resistance, as well as low IGF-I, have been implicated in the pathogenesis of cardiovascular disease. Little is known about…”
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Long-term detrimental consequences of the onset of type 1 diabetes on annual earnings—evidence from annual registry data in 1990-2005
Published in Diabetologia (2010)“…Aims/hypothesis Young adults in the early stages of their participation in the labour market may be particularly vulnerable to the effects of onset of a…”
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Human aortic smooth muscle cells are insulin resistant at the receptor level but sensitive to IGF1 and IGF2
Published in Journal of molecular endocrinology (01-12-2009)“…Whether insulin, at physiological concentrations, has direct effects on vascular smooth muscle cells (VSMCs) remains controversial. Our aim was to characterize…”
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Human microvascular endothelial cells are sensitive to IGF-I but resistant to insulin at the receptor level
Published in Molecular and cellular endocrinology (16-12-2008)“…Human microvascular endothelial cells (HMVEC) are sensitive to IGF-I but insulin resistant and express several times more IGF-I receptors (IGF-IR) than insulin…”
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The incidence of Type I diabetes has not increased but shifted to a younger age at diagnosis in the 0-34 years group in Sweden 1983 to 1998
Published in Diabetologia (2002)“…To analyse the incidence of Type I (insulin-dependent) diabetes mellitus in the 0-34 years age group in Sweden 1983-1998. Incidence and cumulative incidence…”
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Prognostic factors for the course of β cell function in autoimmune diabetes
Published in The journal of clinical endocrinology and metabolism (2000)“…This study presents a 2-yr follow-up of 281 patients, aged 15-34 yr, diagnosed with diabetes between 1992 and 1993. At diagnosis, 224 (80%) patients were…”
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Declining Incidence of Nephropathy in Insulin-Dependent Diabetes Mellitus
Published in The New England journal of medicine (06-01-1994)“…Diabetic nephropathy is the most common cause of end-stage renal failure in the Western world 1 . Among patients with insulin-dependent diabetes, those with…”
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Variable sensitivity to the glucocorticoid activity of cortisol in patients with primary adrenal insufficiency: assessment with ACTH profiles
Published in Hormone and metabolic research (01-12-2010)“…Our aim was to investigate the usefulness of circulating levels of adrenocorticotropic hormone (ACTH) and also salivary cortisol to monitor cortisone…”
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Intraoperative muscle and fat metabolism in diabetic patients during coronary artery bypass grafting surgery: a parallel microdialysis and organ balance study
Published in British journal of anaesthesia : BJA (01-08-2009)“…Surgical trauma causes stress and inflammatory reactions with elevated serum free fatty acids (FFA) and glucose levels characteristic of intraoperative insulin…”
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Overweight, hyperglycemia and tobacco use are modifiable risk factors for onset of retinopathy 9 and 17 years after the diagnosis of diabetes – A retrospective observational nation-wide cohort study
Published in Diabetes research and clinical practice (2017)“…Background: The aims of this study were to estimate the risk for diabetic retinopathy (DR) and to identify risk factors. We investigated a nationwide…”
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