Search Results - "ARNOLD, L. A"

Identification of a novel, fast-acting GABAergic antidepressant by McMurray, K M J, Ramaker, M J, Barkley-Levenson, A M, Sidhu, P S, Elkin, P K, Reddy, M K, Guthrie, M L, Cook, J M, Rawal, V H, Arnold, L A, Dulawa, S C, Palmer, A A

“…Current pharmacotherapies for depression exhibit slow onset, side effects and limited efficacy. Therefore, identification of novel fast-onset antidepressants…”
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Differential regulation of epidermal function by VDR coactivators by Bikle, D.D., Teichert, A., Arnold, L.A., Uchida, Y., Elias, P.M., Oda, Y.

“…The transcriptional activity of the vitamin D receptor (VDR) is regulated by a number of coactivator and corepressor complexes, which bind to the VDR in a…”
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Clinical and therapeutic observations in aromatic L-amino acid decarboxylase deficiency by SWOBODA, K. J, HYLAND, K, GOLDSTEIN, D. S, KUBAN, K. C. K, ARNOLD, L. A, HOLMES, C. S, LEVY, H. L

“…To elucidate the phenotype in aromatic L-amino acid decarboxylase (AADC) deficiency, a rare autosomal recessive disorder of neurotransmitter synthesis, and…”
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Short-term effects of high-dose 17β-estradiol in postmenopausal PD patients: A crossover study by BLANCHET, P. J, FANG, J, HYLAND, K, ARNOLD, L. A, MOURADIAN, M. M, CHASE, T. N

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Prevention of Estrogen Deficiency–Related Bone Loss With Human Parathyroid Hormone–(1-34): A Randomized Controlled Trial by Finkelstein, Joel S, Klibanski, Anne, Arnold, Amy L, Toth, Thomas L, Hornstein, Mark D, Neer, Robert M

“…CONTEXT.— Short-term intermittent administration of parathyroid hormone (PTH) prevents bone loss from the spine in women treated with a gonadotropin-releasing…”
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Oral phenylalanine loading in dopa-responsive dystonia : A possible diagnostic test by HYLAND, K, FRYBURG, J. S, WILSON, W. G, BEBIN, E. M, ARNOLD, L. A, GUNASEKERA, R. S, JACOBSON, R. D, ROST-RUFFNER, E, TRUGMAN, J. M

“…To determine if there is abnormal phenylalanine and biopterin metabolism in patients with dopa-responsive dystonia (DRD), we measured plasma levels of…”
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Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors by Witkin, J.M., Cerne, R., Wakulchik, M., S., J., Gleason, S.D., Jones, T.M., Li, G., Arnold, L.A., Li, J.-X., Schkeryantz, J.M., Methuku, K.R., Cook, J.M., Poe, M.M.

“…Positive allosteric modulators of GABAA receptors transduce a host of beneficial effects including anxiolytic actions. We have recently shown that…”
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Tetrahydrobiopterin deficiency and dopamine loss in a genetic mouse model of Lesch‐Nyhan disease by Hyland, K., Kasim, S., Egami, K., Arnold, L. A., Jinnah, H. A.

“…Hypoxanthine‐guanine phosphoribosyltransferase (HPRT) is an enzyme that catalyses the conversion of hypoxanthine and guanine into their respective nucleotides…”
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Restricted matrilineal gene flow and regional differentiation among Atlantic salmon ( L.) populations within the Bay of Fundy, eastern Canada by Verspoor, E, O'Sullivan, M, Arnold, A L, Knox, D, Amiro, P G

“…Matrilineal phylogenetic divergence among Atlantic salmon stocks of the Bay of Fundy in south eastern Canada is investigated. Sequence variation in two regions…”
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Design and characterization of Ion sources for CHIP-TRAP by Horana Gamage, M., Arnold, A. L., Bhandari, R., Gamage, N. D., Purcell, Z., Sandler, R., Redshaw, M.

“…At Central Michigan University, we are developing a high-precision Penning trap mass spectrometer (CHIP-TRAP) for precise mass measurements with stable and…”
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Sonohysterography: a technique for endometrial evaluation by Cullinan, J A, Fleischer, A C, Kepple, D M, Arnold, A L

“…Sonohysterography involves the instillation of sterile saline under continuous sonographic visualization to assess the endometrial cavity. The technique is…”
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Tetrahydrobiopterin and biogenic amine metabolism in the hph-1 mouse by Hyland, K, Gunasekera, R S, Engle, T, Arnold, L A

“…hph-1 mice, which have defective tetrahydrobiopterin biosynthesis due to decreased GTP cyclohydrolase I activity, have been used to investigate the effects of…”
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Increases in bone mineral density after discontinuation of daily human parathyroid hormone and gonadotropin-releasing hormone analog administration in women with endometriosis by FINKELSTEIN, J. S, ARNOLD, A. L

“…Intermittent PTH administration increases spinal bone mineral density (BMD) and prevents bone loss from the hip and total body in young women treated with a…”
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Chronic Exposure to MPTP as a Primate Model of Progressive Parkinsonism: A Pilot Study with a Free Radical Scavenger by Blanchet, P.J., Konitsiotis, S., Hyland, K., Arnold, L.A., Pettigrew, K.D., Chase, T.N.

“…The development of a validated primate model of progressive parkinsonism is a critical step in the evaluation of drugs that might halt or slow progression of…”
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Dihydropteridine reductase deficiency localized to the central nervous system by Blau, N., Thöny, B., Renneberg, A., Arnold, L. A., Hyland, K.

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Oral phenylalanine loading profiles in symptomatic and asymptomatic gene carriers with dopa‐responsive dystonia due to dominantly inherited GTP cyclohydrolase deficiency by Hyland, K., Nygaard, T. G., Trugman, J. M., Swoboda, K. J., Arnold, L. A., Sparagana, S. P.

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Time-dependent effects of levodopa on regional brain dopamine metabolism and lipid peroxidation by Loeffler, D.A, LeWitt, P.A, Juneau, P.L, Camp, D.M, Arnold, L.A, Hyland, K

“…Levodopa treatment in Parkinson’s disease has been suggested to contribute to disease progression through free radical generation. We compared the time course…”
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Enantioselective Copper-Catalyzed Allylic Alkylation with Dialkylzincs Using Phosphoramidite Ligands by Malda, Hinke, van Zijl, Anthoni W, Arnold, Leggy A, Feringa, Ben L

“…In the presence of a catalytic amount of copper salts, cinnamyl halides undergo a regio- and enantioselective SN2‘ alkylation with dialkylzincs using chiral…”
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Relationship between catalase activity, life span and some parameters associated with antioxidant defenses in Drosophila melanogaster by Orr, W C, Arnold, L A, Sohal, R S

“…This study was conducted on Drosophila melanogaster mutants with different levels of catalase activity in order to assess the role of antioxidant defenses in…”
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Defects of biopterin metabolism and biogenic amine biosynthesis: clinical diagnostic, and therapeutic aspects by Hyland, K, Arnold, L A, Trugman, J M

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