Search Results - "ARIYOSHI, Noritaka"
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Validation of the ABCD-GENE score to identify high platelet reactivity in east Asian patients undergoing percutaneous coronary intervention
Published in International journal of cardiology (15-03-2021)“…High platelet reactivity (HPR) is associated with subsequent thrombotic events in patients undergoing percutaneous coronary intervention (PCI). Recently, the…”
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Efficacy of 2.5-mg Prasugrel in Elderly or Low-Body-Weight Patients
Published in Circulation Journal (24-08-2018)“…Background: Due to concern about bleeding complications, a maintenance dose of prasugrel 2.5 mg may be used in elderly or low-body-weight patients in Japan…”
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Differential Impact of Clinical and Genetic Factors on High Platelet Reactivity in Patients with Coronary Artery Disease Treated with Clopidogrel and Prasugrel
Published in Journal of Atherosclerosis and Thrombosis (01-07-2022)“…Aim: High platelet reactivity (HPR) is associated with increased risks of thrombotic events in patients with coronary artery disease. The recently developed…”
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Derivation of a Novel Scoring System Predicting High Platelet Reactivity on Prasugrel in Patients with Coronary Artery Disease
Published in Journal of Atherosclerosis and Thrombosis (01-11-2022)“…Aims: High platelet reactivity (HPR) has been associated with an increased risk of thrombotic events in patients undergoing percutaneous coronary intervention…”
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Impact of chronic kidney disease on platelet inhibition of clopidogrel and prasugrel in Japanese patients
Published in Journal of cardiology (01-05-2017)“…Abstract Background The impact of chronic kidney disease (CKD) on the antiplatelet effect of clopidogrel and low-dose (3.75 mg) prasugrel in Japanese patients…”
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Increased Platelet Inhibition After Switching From Maintenance Clopidogrel to Prasugrel in Japanese Patients With Stable Coronary Artery Disease
Published in Circulation Journal (2015)“…Background:The pharmacodynamic effects of changing from standard-dose clopidogrel to low-dose (3.75 mg) prasugrel in Japanese patients are largely…”
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High residual platelet reactivity after switching from clopidogrel to low-dose prasugrel in Japanese patients with end-stage renal disease on hemodialysis
Published in Journal of cardiology (01-01-2019)“…•Three fourths of Japanese hemodialysis (HD) patients showed high on-treatment platelet reactivity (HPR) under clopidogrel.•More than half of Japanese HD…”
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Effect of CYP3A53 genetic variant on the metabolism of direct-acting antivirals in vitro: a different effect on asunaprevir versus daclatasvir and beclabuvir
Published in Journal of human genetics (01-01-2020)“…Direct-acting antivirals, asunaprevir (ASV), daclatasvir (DCV), and beclabuvir (BCV) are known to be mainly metabolized by CYP3A enzymes; however, the…”
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Enhanced Susceptibility of HLA-mediated Ticlopidine-induced Idiosyncratic Hepatotoxicity by CYP2B6 Polymorphism in Japanese
Published in DRUG METABOLISM AND PHARMACOKINETICS (01-01-2010)“…Hepatotoxicity is the most frequent adverse drug reaction (ADR) in Japanese treated with ticlopidine (TP). We investigated the relationship between CYP2B6…”
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Functional characterization of seven single-nucleotide polymorphisms of the steroid sulfatase gene found in a Japanese population
Published in Journal of human genetics (01-05-2013)“…Steroid sulfatase (STS) is an enzyme that hydrolyzes steroid sulfates such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate. STS has a key role…”
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An extremely high bioavailability of orally administered vancomycin in a patient with severe colitis and renal insufficiency
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-12-2017)“…Because there is little absorption of orally administered vancomycin hydrochloride (VCM) through the normal intestinal microvillus membrane, the…”
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Platelet inhibition after loading dose of prasugrel in patients with ST-elevation and non-ST-elevation acute coronary syndrome
Published in Cardiovascular intervention and therapeutics (01-07-2018)“…The PRASFIT-ACS study showed the antiplatelet effect 2–4 h after prasugrel loading. However, there is little information about the antiplatelet effect <2 h…”
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Kefiran Reduces Atherosclerosis in Rabbits Fed a High Cholesterol Diet
Published in Journal of Atherosclerosis and Thrombosis (01-01-2010)“…Aim: Kefiran is an exopolysaccharide produced by Lactobacillus kefiranofaciens, and has been proposed to have many health-promoting properties. We investigated…”
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Drug therapy and pharmacogenetics
Published in Arerugi (01-07-2012)Get more information
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15
Development of a Simple Method for Detection of the HLA-A31:01 Allele
Published in DRUG METABOLISM AND PHARMACOKINETICS (2013)“…It is known that rare but severe cutaneous adverse drug reactions (cADRs), such as Stevens- Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and…”
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Genetic and non-genetic factors responsible for antiplatelet effects of clopidogrel in Japanese patients undergoing coronary stent implantation: An algorithm to predict on-clopidogrel platelet reactivity
Published in Thrombosis research (01-10-2014)“…Abstract Introduction Antiplatelet effects of clopidogrel appear to be affected by various factors including genetic polymorphism. So far, there has been…”
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Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells
Published in Drug metabolism and pharmacokinetics (01-04-2015)“…Estrone-3-sulfate (E1S) is thought to be a major estrogen precursor in estrogen receptor (ER)-positive breast cancer. Since E1S is a hydrophilic compound, the…”
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Genetic Polymorphism of CYP2A6 Gene and Tobacco-induced Lung Cancer Risk in Male Smokers
Published in Cancer epidemiology, biomarkers & prevention (01-09-2002)“…Cytochrome P450 2A6 (CYP2A6) is the principal enzyme involved in the metabolic activation of tobacco-specific nitrosamines to their ultimate carcinogenic forms…”
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Application of Akaike information criterion to evaluate warfarin dosing algorithm
Published in Thrombosis research (01-09-2010)“…Abstract Introduction Several factors responsible for inter-individual differences in response to warfarin have been confirmed; however, unidentified factors…”
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Six Novel Single Nucleotide Polymorphisms of the Steroid Sulfatase Gene in a Japanese Population
Published in DRUG METABOLISM AND PHARMACOKINETICS (01-01-2010)“…Steroid sulfatase (STS) is a microsomal enzyme responsible for the formation of 3β-hydroxysteroid from the corresponding sulfate conjugates. Screening of all…”
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