Search Results - "ARIAS, J. L"

Drug targeting strategies in cancer treatment: an overview by Arias, J L

“…Classic chemotherapy his little or no specificity for cancer cells, normally resulting in low accumulation at the tumor region (inefficacy), and in severe side…”
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Lipid-based drug delivery systems for cancer treatment by Arias, J L, Clares, B, Morales, M E, Gallardo, V, Ruiz, M A

“…It is a fact that chemotherapy agents have little specificity for cancer cells, this leading to low concentrations into the tumor interstititum and severe side…”
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Biogeochemical changes at the sediment–water interface during redox transitions in an acidic reservoir: exchange of protons, acidity and electron donors and acceptors by Corzo, A., Jiménez-Arias, J. L., Torres, E., García-Robledo, E., Lara, M., Papaspyrou, S.

“…Redox transitions induced by seasonal changes in water column O₂ concentration can have important effects on solutes exchange across the sediment–water…”
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Increase of glucocorticoid receptor expression after environmental enrichment: Relations to spatial memory, exploration and anxiety-related behaviors by Sampedro-Piquero, P, Begega, A, Arias, J.L

“…Abstract Environmental enrichment (EE) produces a remarkable degree of structural and functional plasticity in the hippocampus and possible mediators of these…”
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Magnetic colloids as drug vehicles by Durán, J D G, Arias, J L, Gallardo, V, Delgado, A V

“…This review article is a description of the present status of magnetic drug delivery systems (DDS). These are colloidal dispersions of composite nanoparticles…”
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Drug targeting to cancer by nanoparticles surface functionalized with special biomolecules by Holgado, M A, Martin-Banderas, L, Alvarez-Fuentes, J, Fernandez-Arevalo, M, Arias, J L

“…Nanoparticulate-based drug carriers have been developed to overcome the problems of conventional anticancer pharmacotherapy, i.e., the little specificity and…”
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Pain extent is associated with Central Sensitization Inventory but not widespread pressure pain sensitivity or psychological variables in women with fibromyalgia by Cigarán-Méndez, M, Úbeda-D'Ocasar, E, Arias-Buría, JL, Fernández-de-Las-Peñas, C, Barbero, M, Gallego-Sendarrubias, GM, Valera-Calero, JA

“…To investigate the relationship between pain extent, as a clinical sign of central sensitization, and clinical, psychological, and pressure sensitivity in…”
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Benthic metal fluxes and sediment diagenesis in a water reservoir affected by acid mine drainage: A laboratory experiment and reactive transport modeling by Torres, E., Ayora, C., Jiménez-Arias, J.L., García-Robledo, E., Papaspyrou, S., Corzo, A.

“…Reservoirs are one of the primary water supply sources. Knowledge of the metal fluxes at the water–sediment interfaces of reservoirs is essential for…”
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Polycyclic aromatic hydrocarbons in rice grain dried by different processes: Evaluation of a quick, easy, cheap, effective, rugged and safe extraction method by Escarrone, A.L.V., Caldas, S.S., Furlong, E.B., Meneghetti, V.L., Fagundes, C.A.A., Arias, J.L.O., Primel, E.G.

“…•Optimisation of a method for analysis of 16 PAHs in rice samples is proposed.•Rice can be contaminated during processes especially dried with burning…”
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Selective involvement of the goldfish lateral pallium in spatial memory by Broglio, C., Rodríguez, F., Gómez, A., Arias, J.L., Salas, C.

“…The involvement of the main pallial subdivisions of the teleost telencephalic pallium in spatial cognition was evaluated in a series of three experiments. The…”
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Egocentric and allocentric spatial memory in healthy aging: performance on real-world tasks by Fernandez-Baizan, C, Diaz-Caceres, E, Arias, J L, Mendez, M

“…Although normal aging has been related to several cognitive difficulties, other processes have been studied less, such as spatial memory. Our aim was to…”
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Age-dependent effects of environmental enrichment on brain networks and spatial memory in Wistar rats by Sampedro-Piquero, P, Begega, A, Zancada-Menendez, C, Cuesta, M, Arias, J.L

“…Highlights • EE improved the performance in young and aged rats. • The effect of EE on the distance travelled depending on the age of the animals. • EE had a…”
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Effects of green macroalgal blooms on the meiofauna community structure in the Bay of Cádiz by Bohórquez, J., Papaspyrou, S., Yúfera, M., van Bergeijk, S.A., García-Robledo, E., Jiménez-Arias, J.L., Bright, M., Corzo, A.

“…► Intertidal meiofauna in Cadiz Bay were dominated by nematodes in all seasons. ► Macroalgae bloom increased further the dominance of nematodes. ► Community…”
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Spatial learning of the water maze: Progression of brain circuits mapped with cytochrome oxidase histochemistry by Conejo, N.M., González-Pardo, H., Gonzalez-Lima, F., Arias, J.L.

“…The progression of brain circuits involved in spatial learning tasks is still a matter of debate. In addition, the participation of individual regions at…”
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Effects of forced exercise on spatial memory and cytochrome c oxidase activity in aged rats by Sampedro-Piquero, P, Zancada-Menendez, C, Begega, A, Mendez, M, Arias, J.L

“…Abstract We have studied the effects of exercise in aged rats (18 months-old) on spatial learning and changes in neuronal metabolic activity associated with…”
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The recognition of a novel-object in a novel context leads to hippocampal and parahippocampal c-Fos involvement by Arias, N., Méndez, M., Arias, JL

“…•Role of context change in a one-trial-novel object recognition task was studied.•Two conditions:OR-NORMAL(sample and probe same context):OR-CONTEXT…”
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Preparation and characterization of carbonyl iron/poly(butylcyanoacrylate) core/shell nanoparticles by Arias, J.L., Gallardo, V., Linares-Molinero, F., Delgado, A.V.

“…In this article a method is described to prepare composite colloidal nanoparticles, consisting of a magnetic core (carbonyl iron) and a biodegradable polymeric…”
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Drug delivery to inflammation based on nanoparticles surface decorated with biomolecules by Clares, B, Ruiz, M A, Gallardo, V, Arias, J L

“…Anti-inflammatory molecules often display little affinity for inflamed tissues, leading to low accumulation into this site of action (and inefficiency), and…”
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Similarities and differences between the brain networks underlying allocentric and egocentric spatial learning in rat revealed by cytochrome oxidase histochemistry by Rubio, S, Begega, A, Méndez, M, Méndez-López, M, Arias, J.L

“…Highlights ► The functional interaction of brain regions is modulated by task requirements. ► Allocentric and egocentric spatial tasks increased CO activity in…”
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Synthesis of lidocaine-loaded PLGA microparticles by flow focusing Effects on drug loading and release properties by HOLGADO, M. A, ARIAS, J. L, COZAR, M. J, ALVAREZ-FUENTES, J, GANAN-CALVO, A. M, FERNANDEZ-AREVALO, M

“…In the present work, two methods for the preparation of lidocaine-loaded PLGA microparticles are compared. The differences between the polymeric particles…”
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