Search Results - "ARBOLEDA, Jane"

HER-2/neu and Urokinase-Type Plasminogen Activator and Its Inhibitor in Breast Cancer by KONECNY, Gottfried, UNTCH, Michael, SLAMON, Dennis, PEGRAM, Mark, ARBOLEDA, Jane, WILSON, Cindy, KAHLERT, Stephen, BOETTCHER, Berit, FELBER, Margrit, BERYT, Malgorzota, LUDE, Sandra, HEPP, Hermann

“…Purpose: Recent studies suggest that HER-2/neu specifically promotes the invasive capacity of tumor cells by up-regulating secretion of the proteolytic enzyme,…”
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The Next Journey: Moving Forward After Cancer Diagnosis and Treatment by Arboleda, Jane, Vazquez, Adrienne

“…Oncology healthcare providers have an obligation to support cancer survivors, not just during active treatment, but also long after they have completed…”
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Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib by O'Brien, Neil A, Browne, Brigid C, Chow, Lucy, Wang, Yuhua, Ginther, Charles, Arboleda, Jane, Duffy, Michael J, Crown, John, O'Donovan, Norma, Slamon, Dennis J

“…Trastuzumab and lapatinib provide clinical benefit to women with human epidermal growth factor receptor 2 (HER)-positive breast cancer. However, not all…”
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Candidate Gene in Predicting In Vivo Ovarian Cancer Response to Combination Therapy with Paraplatin and Paclitaxel by Mirhashemi, Ramin, Arena, J Fernando, Frudakis, Tony, Lambrou, Nicholas, Arboleda, Jane, Hunt, Marsha, Medranda, Maria, Averette, Hervy, Penalver, Manuel

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HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells by Pietras, R J, Arboleda, J, Reese, D M, Wongvipat, N, Pegram, M D, Ramos, L, Gorman, C M, Parker, M G, Sliwkowski, M X, Slamon, D J

“…Growth of human breast cells is closely regulated by steroid hormone as well as peptide hormone receptors. Members of both receptor classes are important…”
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Abstract 613: Increased PI3K/AKT activity, which confers resistance to trastuzumab, can be overcome by lapatinib by O'Brien, Neil A., Wang, YuHua, Chow, Lucy, Wilcox, Karen, Browne, Brigid, Crown, John, Arboleda, Jane, Ginther, Charles, Duffy, Michael J., O'Donovan, Norma, Slamon, Dennis J.

“…Trastuzumab and lapatinib provide clinical benefit to women with HER2 positive breast cancer. However, not all patients whose tumors contain the HER2…”
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Overexpression of AKT2/protein kinase Bβ leads to up-regulation of β1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells by ARBOLEDA, M. Jane, LYONS, John F, KABBINAVAR, Fairooz F, BRAY, Mark R, SNOW, Bryan E, AYALA, Raul, DANINO, Mordechai, KARLAN, Beth Y, SLAMON, Dennis J

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Correlation of the survival of ovarian cancer patients with mRNA expression of the 60-kD heat-shock protein HSP-60 by Kimura, E, Enns, R E, Alcaraz, J E, Arboleda, J, Slamon, D J, Howell, S B

“…Ovarian carcinomas express the 60-kD heat-shock protein HSP-60 at widely varying levels in different tumors. The aim of this study was to determine whether…”
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DNA sequence analysis of exons 2 through 11 and immunohistochemical staining are required to detect all known p53 alterations in human malignancies by Casey, G, Lopez, M E, Ramos, J C, Plummer, S J, Arboleda, M J, Shaughnessy, M, Karlan, B, Slamon, D J

“…p53 mutations are the most common genetic alterations found in human malignancies. However current estimates of p53 alterations in cancers may be inaccurate…”
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Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas by Leone, A, Seeger, R C, Hong, C M, Hu, Y Y, Arboleda, M J, Brodeur, G M, Stram, D, Slamon, D J, Steeg, P S

“…Reduced expression of nm23 RNAs/proteins has been associated previously with high tumor metastatic potential. In contrast, we report that regional (state III)…”
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Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells by Arboleda, M Jane, Lyons, John F, Kabbinavar, Fairooz F, Bray, Mark R, Snow, Bryan E, Ayala, Raul, Danino, Mordechai, Karlan, Beth Y, Slamon, Dennis J

“…To determine how AKT2 might contribute to tumor cell progression, a full-length, wild-type, human AKT2/protein kinase B (PKB)beta cDNA was transfected into a…”
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