Search Results - "ARAUJO, Eliana P"

Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance by TSUKUMO, Daniela M. L, CARVALHO-FILHO, Marco A, SAAD, Mario J. A, CARVALHEIRA, José B. C, PRADA, Patricia O, HIRABARA, Sandro M, SCHENKA, André A, ARAUJO, Eliana P, VASSALLO, José, CURI, Rui, VELLOSO, Licio A

“…Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance Daniela M.L. Tsukumo 1 , Marco A. Carvalho-Filho 1 ,…”
Get full text

Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review by Velloso, Lício A., Morari, Joseane, Mendes, Natália F., Jara, Carlos P., Bobbo, Vanessa C. D., Araújo, Eliana P.

“…Interleukin-6 (IL-6) is a unique cytokine that can play both pro- and anti-inflammatory roles depending on the anatomical site and conditions under which it…”
Get full text

Protein C Pretreatment Protects Endothelial Cells from SARS-CoV-2-Induced Activation by Silva, Bruna Rafaela Dos Santos, Sidarta-Oliveira, Davi, Morari, Joseane, Bombassaro, Bruna, Jara, Carlos Poblete, Simeoni, Camila Lopes, Parise, Pierina Lorencini, Proenca-Modena, José Luiz, Velloso, Licio A, Velander, William H, Araújo, Eliana P

“…SARS-CoV-2 can induce vascular dysfunction and thrombotic events in patients with severe COVID-19; however, the cellular and molecular mechanisms behind these…”
Get full text

Maternal obesity damages the median eminence blood-brain barrier structure and function in the progeny: the beneficial impact of cross-fostering by lean mothers by Haddad-Tóvolli, Roberta, Morari, Joseane, Barbizan, Roberta, Bóbbo, Vanessa C, Carraro, Rodrigo S, Solon, Carina, Dragano, Nathalia R, Torsoni, Márcio A, Araujo, Eliana P, Velloso, Licio A

“…Maternal obesity is an important risk factor for obesity, cardiovascular, and metabolic diseases in the offspring. Studies have shown that it leads to…”
Get more information

Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis by Bobbo, Vanessa C, Engel, Daiane F, Jara, Carlos Poblete, Mendes, Natalia F, Haddad-Tovolli, Roberta, Prado, Thais P, Sidarta-Oliveira, Davi, Morari, Joseane, Velloso, Licio A, Araujo, Eliana P

“…Interleukin-6 (IL6) produced in the context of exercise acts in the hypothalamus reducing obesity-associated inflammation and restoring the control of food…”
Get full text

Interleukin-10 is a protective factor against diet-induced insulin resistance in liver by Cintra, Dennys E, Pauli, José R, Araújo, Eliana P, Moraes, Juliana C, de Souza, Cláudio T, Milanski, Marciane, Morari, Joseane, Gambero, Alessandra, Saad, Mário J, Velloso, Licio A

“…Background/Aims The anti-inflammatory cytokine, interleukin-10 (IL-10), is known to exert a protective role in hepatic damage caused by viruses, alcohol,…”
Get full text

Novel fibrin-fibronectin matrix accelerates mice skin wound healing by Jara, Carlos Poblete, Wang, Ou, Paulino do Prado, Thais, Ismail, Ayman, Fabian, Frank Marco, Li, Han, Velloso, Licio A., Carlson, Mark A., Burgess, William, Lei, Yuguo, Velander, William H., Araújo, Eliana P.

“…Plasma fibrinogen (F1) and fibronectin (pFN) polymerize to form a fibrin clot that is both a hemostatic and provisional matrix for wound healing. About 90% of…”
Get full text

Consumption of a Fat-Rich Diet Activates a Proinflammatory Response and Induces Insulin Resistance in the Hypothalamus by De Souza, Cláudio T, Araujo, Eliana P, Bordin, Silvana, Ashimine, Rika, Zollner, Ricardo L, Boschero, Antonio C, Saad, Mário J. A, Velloso, Lício A

“…Obesity has reached epidemic proportions in several regions of the world. General changes in lifestyle, including consumption of fat-rich food, are among the…”
Get full text

Safety and Outcomes Associated with the Pharmacological Inhibition of the Kinin-Kallikrein System in Severe COVID-19 by Mansour, Eli, Palma, Andre C, Ulaf, Raisa G, Ribeiro, Luciana C, Bernardes, Ana Flavia, Nunes, Thyago A, Agrela, Marcus V, Bombassaro, Bruna, Monfort-Pires, Milena, Camargo, Rafael L, Araujo, Eliana P, Brunetti, Natalia S, Farias, Alessandro S, Falcão, Antônio Luís E, Santos, Thiago Martins, Trabasso, Plinio, Dertkigil, Rachel P, Dertkigil, Sergio S, Moretti, Maria Luiza, Velloso, Licio A

“…Coronavirus disease 19 (COVID-19) can develop into a severe respiratory syndrome that results in up to 40% mortality. Acute lung inflammatory edema is a major…”
Get full text

AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus by Coope, Andressa, Milanski, Marciane, Araújo, Eliana P., Tambascia, Marcos, Saad, Mário J.A., Geloneze, Bruno, Velloso, Lício A.

“…Adiponectin exerts an insulin-sensitizing effect, improving insulin action in peripheral tissues and restraining insulin resistance. Here, we explore the…”
Get full text

Pregnancy Protects against Abnormal Gut Permeability Promoted via the Consumption of a High-Fat Diet in Mice by Biolcatti, Caio F, Bobbo, Vanessa C, Solon, Carina, Morari, Joseane, Haddad-Tovolli, Roberta, Araujo, Eliana P, Simoes, Marcela R, Velloso, Licio A

“…The consumption of large amounts of dietary fats and pregnancy are independent factors that can promote changes in gut permeability and the gut microbiome…”
Get full text

Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface-the protective role for BDNF by Ramalho, Albina F, Bombassaro, Bruna, Dragano, Nathalia R, Solon, Carina, Morari, Joseane, Fioravante, Milena, Barbizan, Roberta, Velloso, Licio A, Araujo, Eliana P

“…The consumption of large amounts of dietary fats activates an inflammatory response in the hypothalamus, damaging key neurons involved in the regulation of…”
Get full text

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity by Souza, Gabriela F. P., Solon, Carina, Nascimento, Lucas F., De-Lima-Junior, Jose C., Nogueira, Guilherme, Moura, Rodrigo, Rocha, Guilherme Z., Fioravante, Milena, Bobbo, Vanessa, Morari, Joseane, Razolli, Daniela, Araujo, Eliana P., Velloso, Licio A.

“…Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the…”
Get full text

Evaluation of the efficacy and safety of icatibant and C1 esterase/kallikrein inhibitor in severe COVID-19: study protocol for a three-armed randomized controlled trial by Mansour, Eli, Bueno, Flávia F, de Lima-Júnior, José C, Palma, Andre, Monfort-Pires, Milena, Bombassaro, Bruna, Araujo, Eliana P, Bernardes, Ana Flavia, Ulaf, Raisa G, Nunes, Thyago A, Ribeiro, Luciana C, Falcão, Antônio Luís E, Santos, Thiago Martins, Trabasso, Plinio, Dertkigil, Rachel P, Dertkigil, Sergio S, Maia, Rafael P, Benaglia, Tatiana, Moretti, Maria Luiza, Velloso, Licio A

“…SARS-CoV-2, the virus that causes COVID-19, enters the cells through a mechanism dependent on its binding to angiotensin-converting enzyme 2 (ACE2), a protein…”
Get full text

Wound fluid sampling methods and analysis of cytokine mRNA expression in ulcers from patients with diabetes mellitus by Barbieri, Beatriz, Silva, Amanda, Morari, Joseane, Zanchetta, Flavia C., Oliveira, Bianca, Trott, Alexis, Araújo, Eliana P., Paula, Geraldo, de Oliveira, Beatriz Guitton Renaud Baptista, Pires, Bruna Maiara Ferreira Barreto, Lima, Maria Helena Melo

“…The development of diabetic foot ulcers is a common and severe complication of diabetes that can significantly affect quality of life. The physiological…”
Get full text

Photobiomodulation with Blue Light on Wound Healing: A Scoping Review by Prado, Thais P, Zanchetta, Flávia Cristina, Barbieri, Beatriz, Aparecido, Caroline, Melo Lima, Maria Helena, Araujo, Eliana P

“…Photobiomodulation consists of inducing healing by irradiating light. This scoping review investigates the effect of blue light on the healing process. The…”
Get full text

A Smartphone App for Individual Xylazine/Ketamine Calculation Decreased Anesthesia-Related Mortality in Mice by Jara, Carlos Poblete, Carraro, Rodrigo S., Zanesco, Ariane, Andrade, Beatriz, Moreira, Karina, Nogueira, Guilherme, Souza, Bruno L., Prado, Thais Paulino, Póvoa, Valeria, Velander, William, Velloso, Licio A., Araújo, Eliana P.

“…Currently, experimental animals are widely used in biological and medical research. However, the scientific community has raised several bioethical concerns,…”
Get full text

Plasma Angiotensin II Is Increased in Critical Coronavirus Disease 2019 by Camargo, Rafael L., Bombassaro, Bruna, Monfort-Pires, Milena, Mansour, Eli, Palma, Andre C., Ribeiro, Luciana C., Ulaf, Raisa G., Bernardes, Ana Flavia, Nunes, Thyago A., Agrela, Marcus V., Dertkigil, Rachel P., Dertkigil, Sergio S., Araujo, Eliana P., Nadruz, Wilson, Moretti, Maria Luiza, Velloso, Licio A., Sposito, Andrei C.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) employs angiotensin-converting enzyme 2 (ACE2) as its receptor for cell entrance, and studies have…”
Get full text

Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action by De Souza, Cláudio T, Araújo, Eliana P, Stoppiglia, Luiz F, Pauli, José R, Ropelle, Eduardo, Rocco, Silvana A, Marin, Rodrigo M, Franchini, Kleber G, Carvalheira, José B, Saad, Mário J, Boschero, Antonio C, Carneiro, Everardo M, Velloso, Lício A

“…Recent characterization of the ability of uncoupling protein 2 (UCP2) to reduce ATP production and inhibit insulin secretion by pancreatic β-cells has placed…”
Get full text

Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway by Filiputti, Eliane, Rafacho, Alex, Araújo, Eliana P, Silveira, Leonardo R, Trevisan, Amon, Batista, Thiago M, Curi, Rui, Velloso, Lício A, Quesada, Ivan, Boschero, Antonio C, Carneiro, Everardo M

“…Abstract A regimen of low-protein diet induces a reduction of pancreatic islet function that is associated with development of metabolic disorders including…”
Get full text