Search Results - "ARANY, EDITH"

Differential temporal and spatial post‐injury alterations in cerebral cell morphology and viability by Amtul, Zareen, Najdat, Abdullah N., Hill, David J., Arany, Edith J.

“…Combination of ischemia and β‐amyloid (Aβ) toxicity has been shown to simultaneously increase neuro‐inflammation, endogenous Aβ deposition, and…”
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Fibroblast growth factor receptor 5 (FGFR5) is a co-receptor for FGFR1 that is up-regulated in beta-cells by cytokine-induced inflammation by Regeenes, Romario, Silva, Pamuditha N., Chang, Huntley H., Arany, Edith J., Shukalyuk, Andrey I., Audet, Julie, Kilkenny, Dawn M., Rocheleau, Jonathan V.

“…Fibroblast growth factor receptor-1 (FGFR1) activity at the plasma membrane is tightly controlled by the availability of co-receptors and competing receptor…”
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The spatial cerebral damage caused by larger infarct and β‐amyloid toxicity is driven by the anatomical/functional connectivity by Amtul, Zareen, Frías, Carmen, Randhawa, Jasmine, Hill, David J., Arany, Edith J.

“…Large cerebral infarctions are major predictors of death and severe disability from stroke. Conversely, data concerning these types of infarctions and the…”
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Altered Insulin/Insulin-Like Growth Factor Signaling in a Comorbid Rat model of Ischemia and β-Amyloid Toxicity by Amtul, Zareen, Hill, David J., Arany, Edith J., Cechetto, David F.

“…Ischemic stroke and diabetes are vascular risk factors for the development of impaired memory such as dementia and/or Alzheimer’s disease. Clinical studies…”
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Gestational exposure to cannabidiol leads to glucose intolerance in 3-month-old male offspring by Vanin, Sebastian R, Lee, Kendrick, Nashed, Mina, Tse, Brennan, Sarikahya, Mohammed, Brar, Sukham, Tomy, Gregg, Lucas, Amica-Mariae, Tomy, Thane, Laviolette, Steven R, Arany, Edith J, Hardy, Daniel B

“…Reports in North America suggest that up to 20% of young women (18-24 years) use cannabis during pregnancy. This is concerning given clinical studies indicate…”
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Spatial Dynamics of Vascular and Biochemical Injury in Rat Hippocampus Following Striatal Injury and Aβ Toxicity by Amtul, Zareen, Frías, Carmen, Randhawa, Jasmine, Hill, David J., Arany, Edith J.

“…The hippocampus, a brain region vital for memory and learning, is sensitive to the damage caused by ischemic/hypoxic stroke and is one of the main regions…”
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Acetone Ingestion Mimics a Fasting State to Improve Glucose Tolerance in a Mouse Model of Gestational Hyperglycemia by Szlapinski, Sandra, Strutt, Brenda, Deane, Madeline, Arany, Edith, Bennett, Jamie, Hill, David J

“…Gestational diabetes mellitus results, in part, from a sub-optimal β-cell mass (BCM) during pregnancy. Artemisinins were reported to increase BCM in models of…”
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Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury by Amtul, Zareen, Randhawa, Jasmine, Najdat, Abdullah N., Hill, David J., Arany, Edith J.

“…Besides other causes, ischemia and Alzheimer’s disease pathology is also linked to decreased cerebral blood flow (CBF). There is little or no consensus about…”
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Disruption of the Dopamine D2 Receptor Impairs Insulin Secretion and Causes Glucose Intolerance by García-Tornadú, Isabel, Ornstein, Ana M, Chamson-Reig, Astrid, Wheeler, Michael B, Hill, David J, Arany, Edith, Rubinstein, Marcelo, Becu-Villalobos, Damasia

“…The relationship between antidopaminergic drugs and glucose has not been extensively studied, even though chronic neuroleptic treatment causes hyperinsulinemia…”
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Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters by Beamish, Christine A., Strutt, Brenda J., Arany, Edith J., Hill, David J.

“…Regeneration of insulin-producing β-cells from resident pancreas progenitors requires an understanding of both progenitor identity and lineage plasticity. One…”
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Correction to: Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury by Amtul, Zareen, Randhawa, Jasmine, Najdat, Abdullah N., Hill, David J., Arany, Edith J.

“…The original version of this article contained a random order of part labels for Fig. 4. The correct caption of Fig. 4 with correct order of part labels is…”
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Direct comparison of the abilities of bone marrow mesenchymal versus hematopoietic stem cells to reverse hyperglycemia in diabetic NOD.SCID mice by Arany, Edith J., Waseem, Muhammad, Strutt, Brenda J., Chamson-Reig, Astrid, Bernardo, Adam, Eng, Elizabeth, Hill, David J.

“…Both bone marrow-derived hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC) improve glycemic control in diabetic mice, but their kinetics and…”
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Cellular mechanisms underlying failed beta cell regeneration in offspring of protein-restricted pregnant mice by Cox, Aaron R, Beamish, Christine A, Carter, David E, Arany, Edith J, Hill, David J

“…Low birth weight and poor foetal growth following low protein (LP) exposure are associated with altered islet development and glucose intolerance in adulthood…”
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The Effects of Low Protein During Gestation on Mouse Pancreatic Development and Beta Cell Regeneration by Cox, Aaron R, Gottheil, Stephanie K, Arany, Edith J, Hill, David J

“…Beta cells are partially replaced in neonatal rodents after deletion with streptozotocin (STZ). Exposure of pregnant rats to a low protein (LP) diet impairs…”
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A low protein diet in early life delays the onset of diabetes in the non-obese diabetic mouse by Chamson-Reig, Astrid, Arany, Edith J, Summers, Kelly, Hill, David J

“…Dietary insult in early life can affect the development and future function of the endocrine pancreas. We maintained pregnant non-obese diabetic (NOD) mice on…”
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Altered pancreatic morphology in the offspring of pregnant rats given reduced dietary protein is time and gender specific by Chamson-Reig, Astrid, Thyssen, Sandra M, Arany, Edith, Hill, David J

“…Restriction of dietary protein during gestation and lactation in the rat results in a reduction in β cell mass, insulin content and release in the offspring,…”
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Changes in islet microvasculature following streptozotocin-induced beta-cell loss and subsequent replacement in the neonatal rat by Nicholson, J Michael, Arany, Edith J, Hill, David J

“…Neonatal rats undergo considerable beta-cell regeneration after depletion with streptozotocin (STZ). Since the intraislet vasculature is necessary for both…”
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The effects of low protein during gestation on mouse pancreatic development and beta cell regeneration by Cox, Aaron R, Gottheil, Stephanie K, Arany, Edith J, Hill, David J

“…Beta cells are partially replaced in neonatal rodents after deletion with streptozotocin (STZ). Exposure of pregnant rats to a low protein (LP) diet impairs…”
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GH in the dwarf dopaminergic D2 receptor knockout mouse: somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin by García-Tornadú, Isabel, Rubinstein, Marcelo, Gaylinn, Bruce D, Hill, David, Arany, Edith, Low, Malcolm J, Díaz-Torga, Graciela, Becu-Villalobos, Damasia

“…Recently, the importance of the dopaminergic D2 receptor (D2R) subtype in normal body growth and neonatal GH secretion has been highlighted. Disruption of D2R…”
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Protein Restriction during Early Life in Rats Alters Pancreatic GABAA Receptor Subunit Expression and Glucagon Secretion in Adulthood by Durst, Michelle A., MSc, Lux-Lantos, Victoria A., PhD, Hardy, Daniel B., PhD, Hill, David J., DPhil, Arany, Edith J., MD, PhD

“…Abstract Objective Gamma-aminobutyric acid (GABA) is present in the endocrine pancreas and contributes to insulin and glucagon secretion. Protein restriction…”
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